Glycosynthase mutants of endoglycosidase S2 show potent transglycosylation activity and remarkably relaxed substrate specificity for antibody glycosylation remodeling T Li, X Tong, Q Yang, JP Giddens, LX Wang Journal of Biological Chemistry 291 (32), 16508-16518, 2016 | 133 | 2016 |
Glycoengineering of antibodies for modulating functions LX Wang, X Tong, C Li, JP Giddens, T Li Annual review of biochemistry 88 (1), 433-459, 2019 | 131 | 2019 |
Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines YC Bartsch, X Tong, J Kang, MJ Avendaño, EF Serrano, T García-Salum, ... Science translational medicine 14 (642), eabn9243, 2022 | 113 | 2022 |
Efficacy of mRNA-1273 and Novavax ancestral or BA. 1 spike booster vaccines against SARS-CoV-2 BA. 5 infection in nonhuman primates NK Routhu, SD Stampfer, L Lai, A Akhtar, X Tong, D Yuan, TM Chicz, ... Science Immunology 8 (88), eadg7015, 2023 | 24 | 2023 |
Glycosylation-dependent opsonophagocytic activity of staphylococcal protein A antibodies X Chen, M Shi, X Tong, HK Kim, LX Wang, O Schneewind, D Missiakas Proceedings of the National Academy of Sciences 117 (37), 22992-23000, 2020 | 24 | 2020 |
One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes X Tong, T Li, J Orwenyo, C Toonstra, LX Wang Bioorganic & medicinal chemistry 26 (7), 1347-1355, 2018 | 23 | 2018 |
Preserved Omicron Spike specific antibody binding and Fc-recognition across COVID-19 vaccine platforms Y Bartsch, X Tong, J Kang, MJ Avendaño, EF Serrano, T García-Salum, ... Medrxiv, 2021 | 22 | 2021 |
Waning and boosting of antibody Fc-effector functions upon SARS-CoV-2 vaccination X Tong, RP McNamara, MJ Avendaño, EF Serrano, T García-Salum, ... Nature Communications 14 (1), 4174, 2023 | 18 | 2023 |
Generation and Comparative Kinetic Analysis of New Glycosynthase Mutants from Streptococcus pyogenes Endoglycosidases for Antibody Glycoengineering X Tong, T Li, C Li, LX Wang Biochemistry 57 (35), 5239-5246, 2018 | 17 | 2018 |
Exploring a combined Escherichia coli-based glycosylation and in vitro transglycosylation approach for expression of glycosylated interferon alpha SK Prabhu, Q Yang, X Tong, LX Wang Bioorganic & medicinal chemistry 33, 116037, 2021 | 16 | 2021 |
Waning immunity and IgG4 responses following bivalent mRNA boosting N Lasrado, AY Collier, J Miller, NP Hachmann, J Liu, T Anand, ... Science Advances 10 (8), eadj9945, 2024 | 11 | 2024 |
Simple, rapidly electroassembled thiolated PEG‐based sensor interfaces enable rapid interrogation of antibody titer and glycosylation D Motabar, J Li, S Wang, CY Tsao, X Tong, LX Wang, GF Payne, ... Biotechnology and Bioengineering 118 (7), 2744-2758, 2021 | 10 | 2021 |
Distinct functional humoral immune responses are induced after live attenuated and inactivated seasonal influenza vaccination X Tong, Y Deng, D Cizmeci, L Fontana, MA Carlock, HB Hanley, ... The Journal of Immunology 212 (1), 24-34, 2024 | 8 | 2024 |
Synthesis, binding affinity, and inhibitory capacity of cyclodextrin-based multivalent glycan ligands for human galectin-3 C Ou, C Li, C Feng, X Tong, GR Vasta, LX Wang Bioorganic & medicinal chemistry 72, 116974, 2022 | 4 | 2022 |
Concurrent administration of COVID-19 and influenza vaccines enhances Spike-specific antibody responses SE Barouch, TM Chicz, R Blanc, DR Barbati, LJ Parker, X Tong, W Li, ... Open Forum Infectious Diseases 11 (4), ofae144, 2024 | 2 | 2024 |
Endo-S2 mutants as glycosynthases, method of making and use for glycoengineering of glycoproteins LX Wang, Q Yang, T Li, X Tong US Patent 11,008,601, 2021 | 2 | 2021 |
Waning and boosting of functional humoral immunity to SARS-CoV-2 X Tong, RP McNamara, MJ Avendaño, EF Serrano, T García-Salum, ... bioRxiv, 2022 | 1 | 2022 |
A facile synthesis of a complex type N-glycan thiazoline as an effective inhibitor against the antibody-deactivating endo-β-N-acetylglucosaminidases C Li, S Zhu, X Tong, C Ou, LX Wang Journal of carbohydrate chemistry 36 (8-9), 336-346, 2017 | 1 | 2017 |
Humoral waning kinetics against SARS-CoV-2 is dictated by disease severity and vaccine platform X Tong, B Kellman, MJ Avendano, M Mendu, JC Hsiao, E Serrano, ... medRxiv, 2024 | | 2024 |
Compartment-Specific Antibody Correlates of Protection to SARS-CoV-2 Omicron in Macaques X Tong, Q Wang, W Jung, TM Chicz, R Blanc, LJ Parker, DH Barouch, ... iScience, 2024 | | 2024 |