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Jonathan Du
Titolo
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Anno
A guide to in silico drug design
Y Chang, BA Hawkins, JJ Du, PW Groundwater, DE Hibbs, F Lai
Pharmaceutics 15 (1), 49, 2023
1152023
Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides
B Trastoy, JJ Du, EH Klontz, C Li, JO Cifuente, LX Wang, EJ Sundberg, ...
Nature communications 11 (1), 899, 2020
382020
Using electron density to predict synthon formation in a 4-hydroxybenzoic acid: 4, 4′-bipyridine cocrystal
JJ Du, SA Stanton, PA Williams, JA Ong, PW Groundwater, J Overgaard, ...
Crystal Growth & Design 18 (3), 1786-1798, 2018
282018
Structural insights into the mechanisms and specificities of IgG-active endoglycosidases
JJ Du, EH Klontz, ME Guerin, B Trastoy, EJ Sundberg
Glycobiology 30 (4), 268-279, 2020
262020
An analysis of the experimental and theoretical charge density distributions of the piroxicam–saccharin co-crystal and its constituents
JJ Du, L Váradi, PA Williams, PW Groundwater, J Overgaard, JA Platts, ...
RSC advances 6 (85), 81578-81590, 2016
222016
A comparison of the experimental and theoretical charge density distributions in two polymorphic modifications of piroxicam
F Lai, JJ Du, PA Williams, L Váradi, D Baker, PW Groundwater, ...
Physical Chemistry Chemical Physics 18 (41), 28802-28818, 2016
202016
Mechanism of antibody-specific deglycosylation and immune evasion by Streptococcal IgG-specific endoglycosidases
B Trastoy, JJ Du, JO Cifuente, L Rudolph, M García-Alija, EH Klontz, ...
Nature Communications 14 (1), 1705, 2023
182023
Mechanism of cooperative N-glycan processing by the multi-modular endoglycosidase EndoE
M García-Alija, JJ Du, I Ordóñez, A Diz-Vallenilla, A Moraleda-Montoya, ...
Nature Communications 13 (1), 1137, 2022
152022
Sculpting therapeutic monoclonal antibody N-glycans using endoglycosidases
B Trastoy, JJ Du, M García-Alija, C Li, EH Klontz, LX Wang, EJ Sundberg, ...
Current opinion in structural biology 72, 248-259, 2022
152022
First nondiscriminating translocator protein ligands produced from a carbazole scaffold
HWA Cheng, R Sokias, EL Werry, LM Ittner, TA Reekie, J Du, Q Gao, ...
Journal of Medicinal Chemistry 62 (17), 8235-8248, 2019
152019
Experimental and theoretical charge density distribution in pigment yellow 101
JJ Du, L Váradi, J Tan, Y Zhao, PW Groundwater, JA Platts, DE Hibbs
Physical Chemistry Chemical Physics 17 (6), 4677-4686, 2015
142015
The role of adjuvants in overcoming antibacterial resistance due to enzymatic drug modification
C El-Khoury, E Mansour, Y Yuliandra, F Lai, BA Hawkins, JJ Du, ...
RSC Medicinal Chemistry 13 (11), 1276-1299, 2022
132022
Exploring the Solubility of the Carbamazepine–Saccharin Cocrystal: A Charge Density Study
JJ Du, SA Stanton, S Fakih, BA Hawkins, PA Williams, PW Groundwater, ...
Crystal Growth & Design 21 (8), 4259-4275, 2018
132018
Monoclinic paracetamol vs. Paracetamol-4, 4′-bipyridine co-crystal; what is the difference? a charge density study
JJ Du, F Lai, L Váradi, PA Williams, PW Groundwater, JA Platts, DE Hibbs, ...
Crystals 8 (1), 46, 2018
122018
Modulating antibody effector functions by Fc glycoengineering
M García-Alija, B Van Moer, DE Sastre, T Azzam, JJ Du, B Trastoy, ...
Biotechnology Advances 67, 108201, 2023
112023
Understanding Hygroscopicity of Theophylline via a Novel Cocrystal Polymorph: A Charge Density Study
SA Stanton, JJ Du, F Lai, G Stanton, BA Hawkins, JA Ong, ...
The Journal of Physical Chemistry A 125 (45), 9736-9756, 2021
112021
A guide to in Silico Drug Design. Pharmaceutics 15 (1): 49
Y Chang, BA Hawkins, JJ Du, PW Groundwater, DE Hibbs, F Lai
92023
An experimental and theoretical charge density study of theophylline and malonic acid cocrystallization
BA Hawkins, JJ Du, F Lai, SA Stanton, PA Williams, PW Groundwater, ...
RSC advances 12 (25), 15670-15684, 2022
92022
Glycan biosynthesis ability of gut microbiota increased in primary hypertension patients taking antihypertension medications and potentially promoted by macrophage-adenosine …
S Zheng, C Piao, Y Liu, X Liu, T Liu, X Zhang, J Ren, Y Liu, B Zhu, J Du
Frontiers in Microbiology 12, 719599, 2021
82021
GH18 endo-β-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans
B Trastoy, JJ Du, C Li, M García-Alija, EH Klontz, BR Roberts, ...
Journal of Biological Chemistry 297 (2), 2021
82021
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