A data-driven approach to preprocessing Illumina 450K methylation array data R Pidsley, CC Y Wong, M Volta, K Lunnon, J Mill, LC Schalkwyk BMC genomics 14, 1-10, 2013 | 1133 | 2013 |
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci PL De Jager, G Srivastava, K Lunnon, J Burgess, LC Schalkwyk, L Yu, ... Nature neuroscience 17 (9), 1156-1163, 2014 | 976 | 2014 |
Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration C Cunningham, DC Wilcockson, S Campion, K Lunnon, VH Perry Journal of Neuroscience 25 (40), 9275-9284, 2005 | 953 | 2005 |
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood MN Davies, M Volta, R Pidsley, K Lunnon, A Dixit, S Lovestone, C Coarfa, ... Genome biology 13, 1-14, 2012 | 730 | 2012 |
Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease C Cunningham, S Campion, K Lunnon, CL Murray, JFC Woods, ... Biological psychiatry 65 (4), 304-312, 2009 | 730 | 2009 |
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ... Nature neuroscience 17 (9), 1164-1170, 2014 | 592 | 2014 |
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, ... Archives of general psychiatry 67 (7), 739-748, 2010 | 503 | 2010 |
Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes E Hannon, K Lunnon, L Schalkwyk, J Mill Epigenetics 10 (11), 1024-1032, 2015 | 482 | 2015 |
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ... Molecular psychiatry 19 (1), 88-98, 2014 | 273 | 2014 |
Plasma proteins predict conversion to dementia from prodromal disease A Hye, J Riddoch‐Contreras, AL Baird, NJ Ashton, C Bazenet, R Leung, ... Alzheimer's & Dementia 10 (6), 799-807. e2, 2014 | 253 | 2014 |
A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status S Sood, IJ Gallagher, K Lunnon, E Rullman, A Keohane, H Crossland, ... Genome biology 16, 1-17, 2015 | 226 | 2015 |
A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex SJ Marzi, SK Leung, T Ribarska, E Hannon, AR Smith, E Pishva, ... Nature neuroscience 21 (11), 1618-1627, 2018 | 195 | 2018 |
Inflammatory proteins in plasma are associated with severity of Alzheimer’s disease R Leung, P Proitsi, A Simmons, K Lunnon, A Güntert, D Kronenberg, ... PloS one 8 (6), e64971, 2013 | 191 | 2013 |
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease SJ Furney, A Simmons, G Breen, I Pedroso, K Lunnon, P Proitsi, ... Molecular psychiatry 16 (11), 1130-1138, 2011 | 178 | 2011 |
Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology RG Smith, E Hannon, PL De Jager, L Chibnik, SJ Lott, D Condliffe, ... Alzheimer's & Dementia 14 (12), 1580-1588, 2018 | 169 | 2018 |
Mitochondrial genes are altered in blood early in Alzheimer's disease K Lunnon, A Keohane, R Pidsley, S Newhouse, J Riddoch-Contreras, ... Neurobiology of aging 53, 36-47, 2017 | 166 | 2017 |
Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood K Lunnon, Z Ibrahim, P Proitsi, A Lourdusamy, S Newhouse, M Sattlecker, ... Journal of Alzheimer's disease 30 (3), 685-710, 2012 | 166 | 2012 |
Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study A Duckworth, MA Gibbons, RJ Allen, H Almond, RN Beaumont, AR Wood, ... The Lancet Respiratory Medicine 9 (3), 285-294, 2021 | 165 | 2021 |
Systemic inflammation modulates Fc receptor expression on microglia during chronic neurodegeneration K Lunnon, JL Teeling, AL Tutt, MS Cragg, MJ Glennie, VH Perry The Journal of Immunology 186 (12), 7215-7224, 2011 | 152 | 2011 |
Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder BPF Rutten, E Vermetten, CH Vinkers, G Ursini, NP Daskalakis, E Pishva, ... Molecular psychiatry 23 (5), 1145-1156, 2018 | 151 | 2018 |