| Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012 | 2665 | 2012 |
| Ewing sarcoma TGP Grünewald, F Cidre-Aranaz, D Surdez, EM Tomazou, E de Álava, ... Nature reviews Disease primers 4 (1), 5, 2018 | 784 | 2018 |
| Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations F Tirode, D Surdez, X Ma, M Parker, MC Le Deley, A Bahrami, Z Zhang, ... Cancer discovery 4 (11), 1342-1353, 2014 | 556 | 2014 |
| Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries V Boeva, C Louis-Brennetot, A Peltier, S Durand, C Pierre-Eugène, ... Nature genetics 49 (9), 1408-1413, 2017 | 458 | 2017 |
| DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ... Nature medicine 23 (3), 386-395, 2017 | 246 | 2017 |
| Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ... Nature medicine 26 (5), 712-719, 2020 | 239 | 2020 |
| Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite TGP Grünewald, V Bernard, P Gilardi-Hebenstreit, V Raynal, D Surdez, ... Nature genetics 47 (9), 1073-1078, 2015 | 204 | 2015 |
| Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden P Peneder, AM Stütz, D Surdez, M Krumbholz, S Semper, M Chicard, ... Nature communications 12 (1), 3230, 2021 | 142 | 2021 |
| Transcriptional programs define intratumoral heterogeneity of Ewing sarcoma at single-cell resolution MM Aynaud, O Mirabeau, N Gruel, S Grossetête, V Boeva, S Durand, ... Cell reports 30 (6), 1767-1779. e6, 2020 | 142 | 2020 |
| Clonally expanded T cells reveal immunogenicity of rhabdoid tumors A Leruste, J Tosello, RN Ramos, A Tauziède-Espariat, S Brohard, ZY Han, ... Cancer cell 36 (6), 597-612. e8, 2019 | 142 | 2019 |
| The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation ZY Han, W Richer, P Fréneaux, C Chauvin, C Lucchesi, D Guillemot, ... Nature communications 7 (1), 10421, 2016 | 119 | 2016 |
| Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis AM El‐Naggar, SP Somasekharan, Y Wang, H Cheng, GL Negri, M Pan, ... EMBO reports 20 (12), e48375, 2019 | 98 | 2019 |
| Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model TZ Minas, D Surdez, T Javaheri, M Tanaka, M Howarth, HJ Kang, J Han, ... Oncotarget 8 (21), 34141, 2016 | 95 | 2016 |
| De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis V Boeva, D Surdez, N Guillon, F Tirode, AP Fejes, O Delattre, E Barillot Nucleic acids research 38 (11), e126-e126, 2010 | 93 | 2010 |
| Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth D Surdez, M Benetkiewicz, V Perrin, ZY Han, G Pierron, S Ballet, ... Cancer research 72 (17), 4494-4503, 2012 | 81 | 2012 |
| Proteomic screens for suppressors of anoikis identify IL1RAP as a promising surface target in Ewing sarcoma HF Zhang, CS Hughes, W Li, JZ He, D Surdez, AM El-Naggar, H Cheng, ... Cancer discovery 11 (11), 2884-2903, 2021 | 76 | 2021 |
| Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility MJ Machiela, TGP Grünewald, D Surdez, S Reynaud, O Mirabeau, ... Nature communications 9 (1), 3184, 2018 | 74 | 2018 |
| STAG2 mutations alter CTCF-anchored loop extrusion, reduce cis-regulatory interactions and EWSR1-FLI1 activity in Ewing sarcoma D Surdez, S Zaidi, S Grossetête, K Laud-Duval, AS Ferre, L Mous, ... Cancer cell 39 (6), 810-826. e9, 2021 | 69 | 2021 |
| Activated ALK signals through the ERK–ETV5–RET pathway to drive neuroblastoma oncogenesis L Lopez-Delisle, C Pierre-Eugène, C Louis-Brennetot, D Surdez, ... Oncogene 37 (11), 1417-1429, 2018 | 69 | 2018 |
| Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes J Musa, F Cidre-Aranaz, MM Aynaud, MF Orth, MML Knott, O Mirabeau, ... Nature communications 10 (1), 4128, 2019 | 65 | 2019 |
Thomas G. P. GrünewaldHopp-Children´s Cancer Center Heidelberg (KiTZ)Email verificata su kitz-heidelberg.de