Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology JM Cicchese, S Evans, C Hult, LR Joslyn, T Wessler, JA Millar, S Marino, ... Immunological reviews 285 (1), 147-167, 2018 | 300 | 2018 |
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis PY Chen, L Qin, G Li, Z Wang, JE Dahlman, J Malagon-Lopez, S Gujja, ... Nature metabolism 1 (9), 912-926, 2019 | 260 | 2019 |
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection S Marino, NA Cilfone, JT Mattila, JJ Linderman, JAL Flynn, DE Kirschner Infection and immunity 83 (1), 324-338, 2015 | 222 | 2015 |
Th17 cytokines differentiate obesity from obesity‐associated type 2 diabetes and promote TNF α production B Ip, NA Cilfone, AC Belkina, J DeFuria, M Jagannathan‐Bogdan, M Zhu, ... Obesity 24 (1), 102-112, 2016 | 142 | 2016 |
M281, an anti‐FcRn antibody: pharmacodynamics, pharmacokinetics, and safety across the full range of IgG reduction in a first‐in‐human study LE Ling, JL Hillson, RG Tiessen, T Bosje, MP van Iersel, DJ Nix, ... Clinical Pharmacology & Therapeutics 105 (4), 1031-1039, 2019 | 132 | 2019 |
Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection NA Cilfone, CR Perry, DE Kirschner, JJ Linderman PloS one 8 (7), e68680, 2013 | 132 | 2013 |
Enhancing retrosynthetic reaction prediction with deep learning using multiscale reaction classification JL Baylon, NA Cilfone, JR Gulcher, TW Chittenden Journal of chemical information and modeling 59 (2), 673-688, 2019 | 125 | 2019 |
Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems NA Cilfone, DE Kirschner, JJ Linderman Cellular and molecular bioengineering 8, 119-136, 2015 | 114 | 2015 |
Chronic mTOR activation induces a degradative smooth muscle cell phenotype G Li, M Wang, AW Caulk, NA Cilfone, S Gujja, L Qin, PY Chen, Z Chen, ... The Journal of clinical investigation 130 (3), 1233-1251, 2020 | 90 | 2020 |
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity–mediated antimicrobial responses with caseation during Mycobacterium … NA Cilfone, CB Ford, S Marino, JT Mattila, HP Gideon, JAL Flynn, ... The Journal of Immunology 194 (2), 664-677, 2015 | 78 | 2015 |
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment E Pienaar, NA Cilfone, PL Lin, V Dartois, JT Mattila, JR Butler, JAL Flynn, ... Journal of theoretical biology 367, 166-179, 2015 | 73 | 2015 |
Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium N Ricard, RP Scott, CJ Booth, H Velazquez, NA Cilfone, JL Baylon, ... Journal of Experimental Medicine 216 (8), 1874-1890, 2019 | 65 | 2019 |
Quantitative systems pharmacology approaches applied to microphysiological systems (MPS): data interpretation and multi‐MPS integration J Yu, NA Cilfone, EM Large, U Sarkar, JS Wishnok, SR Tannenbaum, ... CPT: Pharmacometrics & Systems Pharmacology 4 (10), 585-594, 2015 | 52 | 2015 |
A multi-scale approach to designing therapeutics for tuberculosis JJ Linderman, NA Cilfone, E Pienaar, C Gong, DE Kirschner Integrative Biology 7 (5), 591-609, 2015 | 40 | 2015 |
CPT: pharmacometrics Syst J Yu, NA Cilfone, EM Large, U Sarkar, JS Wishnok, SR Tannenbaum, ... Pharmacol 4 (585), 10.1002, 2015 | 34 | 2015 |
Systems pharmacology approach toward the design of inhaled formulations of rifampicin and isoniazid for treatment of tuberculosis NA Cilfone, E Pienaar, GM Thurber, DE Kirschner, JJ Linderman CPT: pharmacometrics & systems pharmacology 4 (3), 193-203, 2015 | 30 | 2015 |
Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor V Farutin, T Prod’homme, K McConnell, N Washburn, P Halvey, CJ Etzel, ... Arthritis Research & Therapy 21, 1-14, 2019 | 29 | 2019 |
Quantum processor-inspired machine learning in the biomedical sciences RY Li, S Gujja, SR Bajaj, OE Gamel, N Cilfone, JR Gulcher, DA Lidar, ... Patterns 2 (6), 2021 | 25 | 2021 |
Enhancing reproducibility of gene expression analysis with known protein functional relationships: the concept of well-associated protein JR Pradines, V Farutin, NA Cilfone, A Ghavami, E Kurtagic, J Guess, ... PLOS Computational Biology 16 (2), e1007684, 2020 | 3 | 2020 |
Computational modeling of granuloma formation in tuberculosis yields insights into both infection and treatment NA Cilfone, E Pienaar, DE Kirschner, JJ Linderman Biophysical Journal 106 (2), 644a, 2014 | 3 | 2014 |