Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization T McGlone, NEB Briggs, CA Clark, CJ Brown, J Sefcik, AJ Florence Organic Process Research & Development 19 (9), 1186-1202, 2015 | 245 | 2015 |
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations CJ Brown, T McGlone, S Yerdelen, V Srirambhatla, F Mabbott, R Gurung, ... Molecular Systems Design & Engineering 3 (3), 518-549, 2018 | 106 | 2018 |
Establishment of a continuous sonocrystallization process for lactose in an oscillatory baffled crystallizer H Siddique, CJ Brown, I Houson, AJ Florence Organic Process Research & Development 19 (12), 1871-1881, 2015 | 91 | 2015 |
Characterization and modelling of antisolvent crystallization of salicylic acid in a continuous oscillatory baffled crystallizer CJ Brown, JA Adelakun, X Ni Chemical Engineering and Processing: Process Intensification 97, 180-186, 2015 | 82 | 2015 |
Determination of metastable zone width, mean particle size and detectable number density using video imaging in an oscillatory baffled crystallizer CJ Brown, XW Ni CrystEngComm 14 (8), 2944-2949, 2012 | 52 | 2012 |
Online evaluation of paracetamol antisolvent crystallization growth rate with video imaging in an oscillatory baffled crystallizer CJ Brown, X Ni Crystal growth & design 11 (3), 719-725, 2011 | 48 | 2011 |
Evaluation of growth kinetics of antisolvent crystallization of paracetamol in an oscillatory baffled crystallizer utilizing video imaging CJ Brown, XW Ni Crystal growth & design 11 (9), 3994-4000, 2011 | 43 | 2011 |
Engineering of acetaminophen particle attributes using a wet milling crystallisation platform B Ahmed, CJ Brown, T McGlone, DL Bowering, J Sefcik, AJ Florence International Journal of Pharmaceutics 554, 201-211, 2019 | 40 | 2019 |
Spray drying as a reliable route to produce metastable carbamazepine form IV RA Halliwell, RM Bhardwaj, CJ Brown, NEB Briggs, J Dunn, J Robertson, ... Journal of pharmaceutical sciences 106 (7), 1874-1880, 2017 | 34 | 2017 |
Effect of process conditions on particle size and shape in continuous antisolvent crystallisation of lovastatin J McGinty, MWS Chong, A Manson, CJ Brown, A Nordon, J Sefcik Crystals 10 (10), 925, 2020 | 33 | 2020 |
Evaluation of crystallization kinetics of adipic acid in an oscillatory baffled crystallizer CJ Brown, YC Lee, ZK Nagy, X Ni CrystEngComm 16 (34), 8008-8014, 2014 | 32 | 2014 |
A novel integrated workflow for isolation solvent selection using prediction and modeling S Ottoboni, B Wareham, A Vassileiou, M Robertson, CJ Brown, ... Organic Process Research & Development 25 (5), 1143-1159, 2021 | 18 | 2021 |
Evaluation of rate of cyclopentane hydrate formation in an oscillatory baffled column using laser induced fluorescence and energy balance CJ Brown, X Ni Chemical Engineering Journal 157 (1), 131-139, 2010 | 16 | 2010 |
Rapid assessment of crystal nucleation and growth kinetics: comparison of seeded and unseeded experiments A Cashmore, R Miller, H Jolliffe, CJ Brown, M Lee, MD Haw, J Sefcik Crystal Growth & Design 23 (7), 4779-4790, 2023 | 14 | 2023 |
Comparative studies of powder flow predictions using milligrams of powder for identifying powder flow issues T Deng, V Garg, LP Diaz, D Markl, C Brown, A Florence, MSA Bradley International Journal of Pharmaceutics 628, 122309, 2022 | 12 | 2022 |
Machine learning-derived correlations for scale-up and technology transfer of primary nucleation kinetics S Yerdelen, Y Yang, JL Quon, CD Papageorgiou, C Mitchell, I Houson, ... Crystal Growth & Design 23 (2), 681-693, 2023 | 8 | 2023 |
Machine learning approaches to the prediction of powder flow behaviour of pharmaceutical materials from physical properties LP Diaz, CJ Brown, E Ojo, C Mustoe, AJ Florence Digital Discovery 2 (3), 692-701, 2023 | 7 | 2023 |
Temperature correction of spectra to improve solute concentration monitoring by in situ ultraviolet and mid-infrared spectrometries toward isothermal local model performance MWS Chong, T McGlone, CY Chai, NEB Briggs, CJ Brown, F Perciballi, ... Organic Process Research & Development 26 (11), 3096-3105, 2022 | 7 | 2022 |
Direct image feature extraction and multivariate analysis for crystallization process characterization FJS Doerr, CJ Brown, AJ Florence Crystal growth & design 22 (4), 2105-2116, 2022 | 7 | 2022 |
Monitoring crystal breakage in wet milling processes using inline imaging and chord length distribution measurements OS Agimelen, V Svoboda, B Ahmed, J Cardona, J Dziewierz, CJ Brown, ... arXiv preprint arXiv:1703.09186, 2017 | 7 | 2017 |