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Kamakoti P Bhat
Kamakoti P Bhat
Email verificata su pfizer.com
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The replication checkpoint prevents two types of fork collapse without regulating replisome stability
H Dungrawala, KL Rose, KP Bhat, KN Mohni, GG Glick, FB Couch, ...
Molecular cell 59 (6), 998-1010, 2015
4132015
RPA and RAD51: fork reversal, fork protection, and genome stability
KP Bhat, D Cortez
Nature structural & molecular biology 25 (6), 446-453, 2018
3682018
RADX promotes genome stability and modulates chemosensitivity by regulating RAD51 at replication forks
H Dungrawala, KP Bhat, R Le Meur, WJ Chazin, X Ding, SK Sharan, ...
Molecular cell 67 (3), 374-386. e5, 2017
2022017
Epigenetics and beyond: targeting writers of protein lysine methylation to treat disease
KP Bhat, H Ümit Kaniskan, J Jin, O Gozani
Nature Reviews Drug Discovery 20 (4), 265-286, 2021
1782021
RADX modulates RAD51 activity to control replication fork protection
KP Bhat, A Krishnamoorthy, H Dungrawala, EB Garcin, M Modesti, ...
Cell reports 24 (3), 538-545, 2018
1082018
An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance
TJ Hagenbeek, JR Zbieg, M Hafner, R Mroue, JA Lacap, NM Sodir, ...
Nature Cancer 4 (6), 812-828, 2023
952023
High-affinity DNA-binding domains of replication protein A (RPA) direct SMARCAL1-dependent replication fork remodeling
KP Bhat, R Bétous, D Cortez
Journal of Biological Chemistry 290 (7), 4110-4117, 2015
842015
CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
KP Bhat, J Vijay, CK Vilas, J Asundi, J Zou, T Lau, X Cai, M Ahmed, ...
Cell Reports 43 (6), 2024
32024
Regulation of replication fork stability by ssDNA binding proteins
KP Bhat
2018
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