| Reducing acetylated tau is neuroprotective in brain injury MK Shin, E Vázquez-Rosa, Y Koh, M Dhar, K Chaubey, CJ Cintrón-Pérez, ... Cell 184 (10), 2715-2732. e23, 2021 | 145 | 2021 |
| Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer’s disease J Fang, P Zhang, Y Zhou, CW Chiang, J Tan, Y Hou, S Stauffer, L Li, ... Nature Aging 1 (12), 1175-1188, 2021 | 141 | 2021 |
| Network-based prediction of drug–target interactions using an arbitrary-order proximity embedded deep forest X Zeng, S Zhu, Y Hou, P Zhang, L Li, J Li, LF Huang, SJ Lewis, ... Bioinformatics 36 (9), 2805-2812, 2020 | 127 | 2020 |
| Regulation of organic anion transporting polypeptides (OATP) 1B1-and OATP1B3-mediated transport: an updated review in the context of OATP-mediated drug-drug interactions K Alam, A Crowe, X Wang, P Zhang, K Ding, L Li, W Yue International journal of molecular sciences 19 (3), 855, 2018 | 112 | 2018 |
| Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease J Fang, P Zhang, Q Wang, CW Chiang, Y Zhou, Y Hou, J Xu, R Chen, ... Alzheimer's Research & Therapy 14, 1-23, 2022 | 76 | 2022 |
| Multimodal single-cell/nucleus RNA sequencing data analysis uncovers molecular networks between disease-associated microglia and astrocytes with implications for drug … J Xu, P Zhang, Y Huang, Y Zhou, Y Hou, LM Bekris, J Lathia, CW Chiang, ... Genome research 31 (10), 1900-1912, 2021 | 70 | 2021 |
| Downregulation of organic anion transporting polypeptide (OATP) 1B1 transport function by lysosomotropic drug chloroquine: implication in OATP-mediated drug-drug interactions K Alam, S Pahwa, X Wang, P Zhang, K Ding, AH Abuznait, L Li, W Yue Molecular pharmaceutics 13 (3), 839-851, 2016 | 41 | 2016 |
| A new parameter estimator for the Generalized Pareto distribution under the peaks over threshold framework X Zhao, Z Zhang, W Cheng, P Zhang Mathematics 7 (5), 406, 2019 | 34 | 2019 |
| Translational high‐dimensional drug interaction discovery and validation using health record databases and pharmacokinetics models CW Chiang, P Zhang, X Wang, L Wang, S Zhang, X Ning, L Shen, ... Clinical Pharmacology & Therapeutics 103 (2), 287-295, 2018 | 29 | 2018 |
| Examining differences in retention on medication for opioid use disorder: An analysis of Ohio Medicaid data P Zhang, K Tossone, R Ashmead, T Bickert, E Bailey, NJ Doogan, A Mack, ... Journal of Substance Abuse Treatment 136, 108686, 2022 | 24 | 2022 |
| Propensity score‐adjusted three‐component mixture model for drug‐drug interaction data mining in FDA Adverse Event Reporting System X Wang, L Li, L Wang, W Feng, P Zhang Statistics in Medicine 39 (7), 996-1010, 2020 | 24 | 2020 |
| Identification and mechanistic investigation of drug–drug interactions associated with myopathy: a translational approach X Han, SK Quinney, Z Wang, P Zhang, J Duke, Z Desta, JS Elmendorf, ... Clinical Pharmacology & Therapeutics 98 (3), 321-327, 2015 | 23 | 2015 |
| A novel perioperative multidose methadone-based multimodal analgesic strategy in children achieved safe and low analgesic blood methadone levels enabling opioid-sparing … S Sadhasivam, BW Aruldhas, S Packiasabapathy, BR Overholser, ... Anesthesia & Analgesia 133 (2), 327-337, 2021 | 22 | 2021 |
| Translational biomedical informatics and pharmacometrics approaches in the drug interactions research P Zhang, HY Wu, CW Chiang, L Wang, S Binkheder, X Wang, D Zeng, ... CPT: pharmacometrics & systems pharmacology 7 (2), 90-102, 2018 | 22 | 2018 |
| Mining and visualizing high-order directional drug interaction effects using the FAERS database X Yao, T Tsang, Q Sun, S Quinney, P Zhang, X Ning, L Li, L Shen BMC medical informatics and decision making 20, 1-11, 2020 | 20 | 2020 |
| Graphic mining of high‐order drug interactions and their directional effects on myopathy using electronic medical records L Du, A Chakraborty, CW Chiang, L Cheng, SK Quinney, H Wu, P Zhang, ... CPT: pharmacometrics & systems pharmacology 4 (8), 481-488, 2015 | 20 | 2015 |
| Artificial intelligence and open science in discovery of disease-modifying medicines for Alzheimer’s disease F Cheng, F Wang, J Tang, Y Zhou, Z Fu, P Zhang, JL Haines, JB Leverenz, ... Cell Reports Medicine 5 (2), 2024 | 19 | 2024 |
| SARS-CoV-2 infection, hospitalization, and death in vaccinated and infected individuals by age groups in Indiana, 2021‒2022 W Tu, P Zhang, A Roberts, KS Allen, J Williams, P Embi, S Grannis American Journal of Public Health 113 (1), 96-104, 2023 | 19 | 2023 |
| Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans D Lai, TH Schwantes-An, M Abreu, G Chan, V Hesselbrock, C Kamarajan, ... Translational psychiatry 12 (1), 266, 2022 | 18 | 2022 |
| A Mixture Dose–Response Model for Identifying High‐Dimensional Drug Interaction Effects on Myopathy Using Electronic Medical Record Databases P Zhang, L Du, L Wang, M Liu, L Cheng, CW Chiang, HY Wu, SK Quinney, ... CPT: pharmacometrics & systems pharmacology 4 (8), 474-480, 2015 | 18 | 2015 |