The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer TK Sears, JM Angelastro Oncotarget 8 (48), 84595, 2017 | 51 | 2017 |
Postoperative risk of IDH-mutant glioma–associated seizures and their potential management with IDH-mutant inhibitors MR Drumm, W Wang, TK Sears, K Bell-Burdett, R Javier, KY Cotton, ... The Journal of Clinical Investigation 133 (12), 2023 | 28 | 2023 |
Repurposing FDA approved drugs inhibiting mitochondrial function for targeting glioma-stem like cells S Datta, T Sears, G Cortopassi, K Woolard, JM Angelastro Biomedicine & Pharmacotherapy 133, 111058, 2021 | 28 | 2021 |
IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat TK Sears, CM Horbinski, KD Woolard Journal of Neuro-Oncology 154 (2), 159-170, 2021 | 13 | 2021 |
Modeling therapy-driven evolution of glioblastoma with patient-derived xenografts M McCord, E Bartom, K Burdett, A Baran, FD Eckerdt, IV Balyasnikova, ... Cancers 14 (22), 5494, 2022 | 12 | 2022 |
Novel mTORC1 inhibitors kill glioblastoma stem cells JA Sandoval, A Tomilov, S Datta, S Allen, R O’Donnell, T Sears, ... Pharmaceuticals 13 (12), 419, 2020 | 11 | 2020 |
Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer SA Allen, S Datta, J Sandoval, A Tomilov, T Sears, K Woolard, ... Mitochondrion 50, 19-24, 2020 | 10 | 2020 |
The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. Oncotarget 8, 84595–84609 TK Sears, JM Angelastro | 6 | 2017 |
Panobinostat effectively increases histone acetylation and alters chromatin accessibility landscape in canine embryonic fibroblasts but does not enhance cellular reprogramming M Moshref, M Questa, V Lopez-Cervantes, TK Sears, RL Greathouse, ... Frontiers in Veterinary Science 8, 716570, 2021 | 4 | 2021 |
The novel DNA cross-linking agent KL-50 is active against patient-derived models of new and recurrent post-temozolomide mismatch repair-deficient glioblastoma M McCord, T Sears, W Wang, R Chaliparambil, S An, J Sarkaria, ... Neuro-Oncology, noae257, 2024 | 2 | 2024 |
R132H IDH1 sensitizes glioma to the antiproliferative and cytotoxic effects of BET inhibition TK Sears, KD Woolard Journal of Cancer Research and Clinical Oncology 148 (9), 2275-2285, 2022 | 2 | 2022 |
The HDAC inhibitor panobinostat elicits preferential cytotoxic and antiproliferative effects in IDH mutant glioblastoma TK Sears, KD Woolard Cancer Research 80 (16_Supplement), 1917-1917, 2020 | 1 | 2020 |
F3 expression drives sensitivity to the antibody-drug conjugate tisotumab vedotin in glioblastoma TK Sears, W Wang, M Drumm, D Unruh, M McCord, C Horbinski | | 2024 |
IMMU-54. THERAPEUTIC TARGETING OF STING IN MENINGIOMAS M Youngblood, S Tripathi, H Najem, M Gomez, N Sadagopan, T Sears, ... Neuro-Oncology 26 (Supplement_8), viii164-viii164, 2024 | | 2024 |
DDEL-12. LOCAL DELIVERY OF CHEMOTHERAPIES VIA BIORESORBABLE IMPLANT IN MENINGIOMAS M Youngblood, Z Hu, K Nandoliya, V Thirunavu, W Wang, S An, ... Neuro-Oncology 26 (Supplement_8), viii123-viii123, 2024 | | 2024 |
EXTH-28. ISOCITRATE DEHYDROGENASE MUTATIONS PREDICT SENSITIVITY TO HISTONE DEACETYLASE INHIBITION AND ENHANCED HISTONE ACETYLATION DYNAMICS ONLY IN THE CONTEXT OF GLIOMA T Sears, M Drumm, W Wang, C Horbinski Neuro-Oncology 25 (Suppl 5), v229, 2023 | | 2023 |
ISOCITRATE DEHYDROGENASE MUTATIONS PREDICT SENSITIVITY TO HISTONE DEACETYLASE INHIBITION AND ENHANCED HISTONE ACETYLATION DYNAMICS ONLY IN THE CONTEXT OF GLIOMA T Sears, M Drumm, W Wang, C Horbinski NEURO-ONCOLOGY 25, 2023 | | 2023 |
EXPLOITING EPIGENETIC DYSREGULATION IN ISOCITRATE DEHYDROGENASE MUTANT GLIOMA VIA THE USE OF HISTONE DEACETYLASE INHIBITORS T Sears, M Drumm, A Piunti, C Horbinski NEURO-ONCOLOGY 24, 214-215, 2022 | | 2022 |
CNSC-24. THE EPILEPTIC LANDSCAPE OF IDH MUTANT GLIOMAS M Drumm, W Wang, KB Burdett, T Sears, R Javier, K Cotton, B Webb, ... Neuro-Oncology 24 (Supplement_7), vii27-vii27, 2022 | | 2022 |
Preclinical and Clinical Characteristics of Seizures in IDH Mutant Gliomas M Drumm, W Wang, K Bell-Burdett, T Sears, R Javier, K Cotton, B Webb, ... JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 81 (6), 439-440, 2022 | | 2022 |