Segui
Thomas K Sears
Titolo
Citata da
Citata da
Anno
The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer
TK Sears, JM Angelastro
Oncotarget 8 (48), 84595, 2017
512017
Postoperative risk of IDH-mutant glioma–associated seizures and their potential management with IDH-mutant inhibitors
MR Drumm, W Wang, TK Sears, K Bell-Burdett, R Javier, KY Cotton, ...
The Journal of Clinical Investigation 133 (12), 2023
282023
Repurposing FDA approved drugs inhibiting mitochondrial function for targeting glioma-stem like cells
S Datta, T Sears, G Cortopassi, K Woolard, JM Angelastro
Biomedicine & Pharmacotherapy 133, 111058, 2021
282021
IDH1 mutant glioma is preferentially sensitive to the HDAC inhibitor panobinostat
TK Sears, CM Horbinski, KD Woolard
Journal of Neuro-Oncology 154 (2), 159-170, 2021
132021
Modeling therapy-driven evolution of glioblastoma with patient-derived xenografts
M McCord, E Bartom, K Burdett, A Baran, FD Eckerdt, IV Balyasnikova, ...
Cancers 14 (22), 5494, 2022
122022
Novel mTORC1 inhibitors kill glioblastoma stem cells
JA Sandoval, A Tomilov, S Datta, S Allen, R O’Donnell, T Sears, ...
Pharmaceuticals 13 (12), 419, 2020
112020
Cetylpyridinium chloride is a potent AMP-activated kinase (AMPK) inducer and has therapeutic potential in cancer
SA Allen, S Datta, J Sandoval, A Tomilov, T Sears, K Woolard, ...
Mitochondrion 50, 19-24, 2020
102020
The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer. Oncotarget 8, 84595–84609
TK Sears, JM Angelastro
62017
Panobinostat effectively increases histone acetylation and alters chromatin accessibility landscape in canine embryonic fibroblasts but does not enhance cellular reprogramming
M Moshref, M Questa, V Lopez-Cervantes, TK Sears, RL Greathouse, ...
Frontiers in Veterinary Science 8, 716570, 2021
42021
The novel DNA cross-linking agent KL-50 is active against patient-derived models of new and recurrent post-temozolomide mismatch repair-deficient glioblastoma
M McCord, T Sears, W Wang, R Chaliparambil, S An, J Sarkaria, ...
Neuro-Oncology, noae257, 2024
22024
R132H IDH1 sensitizes glioma to the antiproliferative and cytotoxic effects of BET inhibition
TK Sears, KD Woolard
Journal of Cancer Research and Clinical Oncology 148 (9), 2275-2285, 2022
22022
The HDAC inhibitor panobinostat elicits preferential cytotoxic and antiproliferative effects in IDH mutant glioblastoma
TK Sears, KD Woolard
Cancer Research 80 (16_Supplement), 1917-1917, 2020
12020
F3 expression drives sensitivity to the antibody-drug conjugate tisotumab vedotin in glioblastoma
TK Sears, W Wang, M Drumm, D Unruh, M McCord, C Horbinski
2024
IMMU-54. THERAPEUTIC TARGETING OF STING IN MENINGIOMAS
M Youngblood, S Tripathi, H Najem, M Gomez, N Sadagopan, T Sears, ...
Neuro-Oncology 26 (Supplement_8), viii164-viii164, 2024
2024
DDEL-12. LOCAL DELIVERY OF CHEMOTHERAPIES VIA BIORESORBABLE IMPLANT IN MENINGIOMAS
M Youngblood, Z Hu, K Nandoliya, V Thirunavu, W Wang, S An, ...
Neuro-Oncology 26 (Supplement_8), viii123-viii123, 2024
2024
EXTH-28. ISOCITRATE DEHYDROGENASE MUTATIONS PREDICT SENSITIVITY TO HISTONE DEACETYLASE INHIBITION AND ENHANCED HISTONE ACETYLATION DYNAMICS ONLY IN THE CONTEXT OF GLIOMA
T Sears, M Drumm, W Wang, C Horbinski
Neuro-Oncology 25 (Suppl 5), v229, 2023
2023
ISOCITRATE DEHYDROGENASE MUTATIONS PREDICT SENSITIVITY TO HISTONE DEACETYLASE INHIBITION AND ENHANCED HISTONE ACETYLATION DYNAMICS ONLY IN THE CONTEXT OF GLIOMA
T Sears, M Drumm, W Wang, C Horbinski
NEURO-ONCOLOGY 25, 2023
2023
EXPLOITING EPIGENETIC DYSREGULATION IN ISOCITRATE DEHYDROGENASE MUTANT GLIOMA VIA THE USE OF HISTONE DEACETYLASE INHIBITORS
T Sears, M Drumm, A Piunti, C Horbinski
NEURO-ONCOLOGY 24, 214-215, 2022
2022
CNSC-24. THE EPILEPTIC LANDSCAPE OF IDH MUTANT GLIOMAS
M Drumm, W Wang, KB Burdett, T Sears, R Javier, K Cotton, B Webb, ...
Neuro-Oncology 24 (Supplement_7), vii27-vii27, 2022
2022
Preclinical and Clinical Characteristics of Seizures in IDH Mutant Gliomas
M Drumm, W Wang, K Bell-Burdett, T Sears, R Javier, K Cotton, B Webb, ...
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 81 (6), 439-440, 2022
2022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20