The multiple mechanisms that regulate p53 activity and cell fate A Hafner, ML Bulyk, A Jambhekar, G Lahav Nature reviews Molecular cell biology 20 (4), 199-210, 2019 | 1066 | 2019 |
Visualizing DNA folding and RNA in embryos at single-cell resolution LJ Mateo, SE Murphy, A Hafner, IS Cinquini, CA Walker, AN Boettiger Nature 568 (7750), 49-54, 2019 | 417 | 2019 |
How subtle changes in 3D structure can create large changes in transcription JY Xiao, A Hafner, AN Boettiger Elife 10, e64320, 2021 | 123 | 2021 |
p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics A Hafner, J Stewart-Ornstein, JE Purvis, WC Forrester, ML Bulyk, G Lahav Nature structural & molecular biology 24 (10), 840-847, 2017 | 111 | 2017 |
The spatial organization of transcriptional control A Hafner, A Boettiger Nature Reviews Genetics 24 (1), 53-68, 2023 | 110 | 2023 |
Automated protein-DNA interaction screening of Drosophila regulatory elements K Hens, JD Feuz, A Isakova, A Iagovitina, A Massouras, J Bryois, ... Nature methods 8 (12), 1065-1070, 2011 | 88 | 2011 |
A comprehensive Drosophila melanogaster transcription factor interactome L Shokri, S Inukai, A Hafner, K Weinand, K Hens, A Vedenko, ... Cell reports 27 (3), 955-970. e7, 2019 | 81 | 2019 |
Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos SS Gisselbrecht, LA Barrera, M Porsch, A Aboukhalil, PW Estep III, ... Nature methods 10 (8), 774-780, 2013 | 80 | 2013 |
mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution CM Weber, A Hafner, JG Kirkland, SMG Braun, BZ Stanton, AN Boettiger, ... Nature structural & molecular biology 28 (6), 501-511, 2021 | 77 | 2021 |
Loop stacking organizes genome folding from TADs to chromosomes A Hafner, M Park, SE Berger, SE Murphy, EP Nora, AN Boettiger Molecular cell 83 (9), 1377-1392. e6, 2023 | 71 | 2023 |
Quantifying the central dogma in the p53 pathway in live single cells A Hafner, J Reyes, J Stewart-Ornstein, M Tsabar, A Jambhekar, G Lahav Cell systems 10 (6), 495-505. e4, 2020 | 40 | 2020 |
A yeast one‐hybrid and microfluidics‐based pipeline to map mammalian gene regulatory networks C Gubelmann, SM Waszak, A Isakova, W Holcombe, K Hens, A Iagovitina, ... Molecular systems biology 9 (1), 682, 2013 | 38 | 2013 |
Identification of universal and cell-type specific p53 DNA binding A Hafner, L Kublo, M Tsabar, G Lahav, J Stewart-Ornstein BMC Molecular and Cell Biology 21 (1), 5, 2020 | 30* | 2020 |
Context-dependent transcriptional interpretation of mitogen activated protein kinase signaling in the Drosophila embryo Y Kim, A Iagovitina, K Ishihara, KM Fitzgerald, B Deplancke, ... Chaos: An Interdisciplinary Journal of Nonlinear Science 23 (2), 2013 | 22 | 2013 |
A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation G Llimos, V Gardeux, U Koch, JF Kribelbauer, A Hafner, D Alpern, ... Nature communications 13 (1), 2042, 2022 | 9 | 2022 |
Single-cell chromatin state transitions during epigenetic memory formation T Fujimori, C Rios-Martinez, AR Thurm, MM Hinks, BR Doughty, J Sinha, ... bioRxiv, 2023 | 5 | 2023 |
Super-enhancer interactomes from single cells link clustering and transcription DJ Le, A Hafner, S Gaddam, KC Wang, AN Boettiger bioRxiv, 2024 | 4 | 2024 |
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data L Lee, H Yu, BB Jia, A Jussila, C Zhu, J Chen, L Xie, A Hafner, S Mishra, ... Nature Communications 14 (1), 4873, 2023 | 4 | 2023 |
Abstract LB-101: Combined p53 dynamics and post-translational modifications determine subsequent protein expression and cell fate D Lu, K Holton, A Hafner, C DeHart, J Sikora, H Zhou, A Jambhekar, ... Cancer Research 79 (13_Supplement), LB-101-LB-101, 2019 | | 2019 |
Global and Single Cell Analyses to Connect P53 Dynamics With Gene Expression A Hafner Harvard University, 2017 | | 2017 |