| Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes JR Lin, B Izar, S Wang, C Yapp, S Mei, PM Shah, S Santagata, PK Sorger elife 7, e31657, 2018 | 613 | 2018 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 463 | 2020 |
| Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues SK Saka, Y Wang, JY Kishi, A Zhu, Y Zeng, W Xie, K Kirli, C Yapp, ... Nature biotechnology 37 (9), 1080-1090, 2019 | 393 | 2019 |
| Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains DA Hay, O Fedorov, S Martin, DC Singleton, C Tallant, C Wells, S Picaud, ... Journal of the American Chemical Society 136 (26), 9308-9319, 2014 | 342 | 2014 |
| Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ... Cancer research 75 (23), 5106-5119, 2015 | 255 | 2015 |
| Inflammation activation and resolution in human tendon disease SG Dakin, FO Martinez, C Yapp, G Wells, U Oppermann, BJF Dean, ... Science translational medicine 7 (311), 311ra173-311ra173, 2015 | 249 | 2015 |
| Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ... Nature communications 11 (1), 1459, 2020 | 248 | 2020 |
| 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ... Chemical science 4 (8), 3110-3117, 2013 | 178 | 2013 |
| MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ... Nature methods 19 (3), 311-315, 2022 | 173 | 2022 |
| Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer JR Lin, S Wang, S Coy, YA Chen, C Yapp, M Tyler, MK Nariya, CN Heiser, ... Cell 186 (2), 363-381. e19, 2023 | 166 | 2023 |
| The spatial landscape of progression and immunoediting in primary melanoma at single-cell resolution AJ Nirmal, Z Maliga, T Vallius, B Quattrochi, AA Chen, CA Jacobson, ... Cancer discovery 12 (6), 1518-1541, 2022 | 157 | 2022 |
| Highly selective inhibition of histone demethylases by de novo macrocyclic peptides A Kawamura, M Münzel, T Kojima, C Yapp, B Bhushan, Y Goto, A Tumber, ... Nature communications 8 (1), 14773, 2017 | 156 | 2017 |
| Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies D Reichart, EL Lindberg, H Maatz, AMA Miranda, A Viveiros, N Shvetsov, ... Science 377 (6606), eabo1984, 2022 | 148 | 2022 |
| Potent and selective KDM5 inhibitor stops cellular demethylation of H3K4me3 at transcription start sites and proliferation of MM1S myeloma cells A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ... Cell chemical biology 24 (3), 371-380, 2017 | 135 | 2017 |
| Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities D Rotili, S Tomassi, M Conte, R Benedetti, M Tortorici, G Ciossani, ... Journal of medicinal chemistry 57 (1), 42-55, 2014 | 135 | 2014 |
| [1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains O Fedorov, H Lingard, C Wells, OP Monteiro, S Picaud, T Keates, C Yapp, ... Journal of medicinal chemistry 57 (2), 462-476, 2014 | 113 | 2014 |
| Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR JL Muhlich, YA Chen, C Yapp, D Russell, S Santagata, PK Sorger Bioinformatics 38 (19), 4613-4621, 2022 | 101 | 2022 |
| Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching M Philpott, CM Rogers, C Yapp, C Wells, JP Lambert, C Strain-Damerell, ... Epigenetics & chromatin 7, 1-12, 2014 | 101 | 2014 |
| HSF1 phase transition mediates stress adaptation and cell fate decisions G Gaglia, R Rashid, C Yapp, GN Joshi, CG Li, SL Lindquist, KA Sarosiek, ... Nature Cell Biology 22 (2), 151-158, 2020 | 94 | 2020 |
| High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers JR Lin, YA Chen, D Campton, J Cooper, S Coy, C Yapp, JB Tefft, ... Nature cancer 4 (7), 1036-1052, 2023 | 83 | 2023 |
