Selective uncoupling of individual mitochondria within a cell using a mitochondria-targeted photoactivated protonophore S Chalmers, ST Caldwell, C Quin, TA Prime, AM James, AG Cairns, ... Journal of the American Chemical Society 134 (2), 758-761, 2012 | 137 | 2012 |
Individuals with higher metabolic rates have lower levels of reactive oxygen species in vivo K Salin, SK Auer, AM Rudolf, GJ Anderson, AG Cairns, W Mullen, ... Biology letters 11 (9), 20150538, 2015 | 124 | 2015 |
MitoNeoD: A Mitochondria-Targeted Superoxide Probe MM Shchepinova, AG Cairns, TA Prime, A Logan, AM James, AR Hall, ... Cell chemical biology 24 (10), 1285-1298. e12, 2017 | 89 | 2017 |
Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis K Flentie, GA Harrison, H Tükenmez, J Livny, JAD Good, S Sarkar, ... Proceedings of the National Academy of Sciences 116 (21), 10510-10517, 2019 | 62 | 2019 |
Translation of Diverse Aramid- and 1,3-Dicarbonyl-peptides by Wild Type Ribosomes in Vitro O Ad, KS Hoffman, AG Cairns, AL Featherston, SJ Miller, D Söll, ... ACS central science 5 (7), 1289-1294, 2019 | 58 | 2019 |
The influence of precursor source and thermal parameters upon the formation of beta-phase molybdenum nitride AG Cairns, JG Gallagher, JSJ Hargreaves, D Mckay, E Morrison, JL Rico, ... Journal of Alloys and Compounds 479 (1-2), 851-854, 2009 | 37 | 2009 |
Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes M Kulen, M Lindgren, S Hansen, AG Cairns, C Grundstrom, A Begum, ... Journal of medicinal chemistry 61 (9), 4165-4175, 2018 | 30 | 2018 |
The effect of low levels of dopants upon the formation and properties of beta-phase molybdenum nitride AG Cairns, JG Gallagher, JSJ Hargreaves, D Mckay, JL Rico, K Wilson Journal of Solid State Chemistry 183 (3), 613-619, 2010 | 28 | 2010 |
Targeting mitochondria with small molecules: the preparation of MitoB and MitoP as exomarkers of mitochondrial hydrogen peroxide AG Cairns, SJ McQuaker, MP Murphy, RC Hartley Mitochondrial Medicine: Volume II, Manipulating Mitochondrial Function, 25-50, 2015 | 27 | 2015 |
Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding P Singh, DE Adolfsson, J Ådén, AG Cairns, C Bartens, K Brännström, ... The Journal of organic chemistry 84 (7), 3887-3903, 2019 | 26 | 2019 |
Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress K Salin, SK Auer, EM Villasevil, GJ Anderson, AG Cairns, W Mullen, ... Scientific Reports 7 (1), 41228, 2017 | 25 | 2017 |
Viral mimetic priming enhances α-synuclein-induced degeneration: Implications for Parkinson’s disease LK Olsen, AG Cairns, J Ådén, N Moriarty, S Cabre, VR Alamilla, ... Brain, behavior, and immunity 80, 525-535, 2019 | 23 | 2019 |
Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones P Singh, AG Cairns, DE Adolfsson, J Ådén, UH Sauer, F Almqvist Organic letters 21 (17), 6946-6950, 2019 | 22 | 2019 |
Expanding the palette of phenanthridinium cations AG Cairns, HM Senn, MP Murphy, RC Hartley Chemistry-A European Journal 20 (13), 3742-3751, 2014 | 17 | 2014 |
Regio- and Stereoselective Alkylation of Pyridine-N-oxides: Synthesis of Substituted Piperidines and Pyridines DK Barange, MT Johnson, AG Cairns, R Olsson, F Almqvist Organic letters 18 (24), 6228-6231, 2016 | 11 | 2016 |
Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy AG Cairns, A Vazquez-Romero, M Mahdi Moein, J Ådén, CS Elmore, ... ACS Chemical Neuroscience 9 (11), 2542-2547, 2018 | 9 | 2018 |
The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models R Kelly, AG Cairns, J Ådén, F Almqvist, AP Bemelmans, E Brouillet, ... Biomolecules 11 (11), 1685, 2021 | 8 | 2021 |
Methyl sulfonamide substituents improve the pharmacokinetic properties of bicyclic 2-pyridone based Chlamydia trachomatis inhibitors M Kulén, C Núñez-Otero, AG Cairns, J Silver, AEG Lindgren, E Wede, ... MedChemComm 10 (11), 1966-1987, 2019 | 8 | 2019 |
Synthesis of an azido-tagged low affinity ratiometric calcium sensor ST Caldwell, AG Cairns, M Olson, S Chalmers, M Sandison, W Mullen, ... Tetrahedron 71 (51), 9571-9578, 2015 | 7 | 2015 |
3-Fluorobenzoic acid–4-acetylpyridine (1/1) at 100 K GA Craig, LH Thomas, MS Adam, A Ballantyne, A Cairns, SC Cairns, ... Acta Crystallographica Section E: Structure Reports Online 65 (2), o380-o380, 2009 | 6 | 2009 |