Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes P Kanikarla-Marie, SK Jain Free Radical Biology and Medicine 95, 268-277, 2016 | 206 | 2016 |
Glutathione stimulates vitamin D regulatory and glucose-metabolism genes, lowers oxidative stress and inflammation, and increases 25-hydroxy-vitamin D levels in blood: a novel … SK Jain, R Parsanathan, AE Achari, P Kanikarla-Marie, JA Bocchini Jr Antioxidants & redox signaling 29 (17), 1792-1807, 2018 | 109 | 2018 |
Platelets, circulating tumor cells, and the circulome P Kanikarla-Marie, M Lam, DG Menter, S Kopetz Cancer and Metastasis Reviews 36, 235-248, 2017 | 96 | 2017 |
KRASG12C-independent feedback activation of wild-type RAS constrains KRASG12C inhibitor efficacy MB Ryan, O Coker, A Sorokin, K Fella, H Barnes, E Wong, P Kanikarla, ... Cell reports 39 (12), 2022 | 91 | 2022 |
1, 25 (OH) 2D3 inhibits oxidative stress and monocyte adhesion by mediating the upregulation of GCLC and GSH in endothelial cells treated with acetoacetate (ketosis) P Kanikarla-Marie, SK Jain The Journal of steroid biochemistry and molecular biology 159, 94-101, 2016 | 79 | 2016 |
Hyperketonemia (acetoacetate) upregulates NADPH oxidase 4 and elevates oxidative stress, ICAM-1, and monocyte adhesivity in endothelial cells P Kanikarla-Marie, SK Jain Cellular Physiology and Biochemistry 35 (1), 364-373, 2015 | 75 | 2015 |
L‐cysteine supplementation upregulates glutathione (GSH) and vitamin D binding protein (VDBP) in hepatocytes cultured in high glucose and in vivo in liver, and increases blood … SK Jain, P Kanikarla‐Marie, C Warden, D Micinski Molecular nutrition & food research 60 (5), 1090-1098, 2016 | 49 | 2016 |
Pilot clinical trial of perioperative durvalumab and tremelimumab in the treatment of resectable colorectal cancer liver metastases P Kanikarla Marie, C Haymaker, ER Parra, YU Kim, R Lazcano, S Gite, ... Clinical Cancer Research 27 (11), 3039-3049, 2021 | 42 | 2021 |
The potential role of platelets in the consensus molecular subtypes of colorectal cancer M Lam, J Roszik, P Kanikarla-Marie, JS Davis, J Morris, S Kopetz, ... Cancer and Metastasis Reviews 36, 273-288, 2017 | 41 | 2017 |
Resistance Mechanisms to Anti–Epidermal Growth Factor Receptor Therapy in RAS/RAF Wild-Type Colorectal Cancer Vary by Regimen and Line of Therapy CM Parseghian, R Sun, M Woods, S Napolitano, HM Lee, J Alshenaifi, ... Journal of Clinical Oncology 41 (3), 460-471, 2023 | 38 | 2023 |
Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R G Pradhan, CS Wu, J Han Lee, P Kanikarla, S Guo, VK Yechoor, ... Scientific reports 7 (1), 979, 2017 | 36 | 2017 |
Targeting RAS mutant colorectal cancer with dual inhibition of MEK and CDK4/6 AV Sorokin, P Kanikarla Marie, L Bitner, M Syed, M Woods, G Manyam, ... Cancer Research 82 (18), 3335-3344, 2022 | 34 | 2022 |
Platelet metabolism and other targeted drugs; potential impact on immunotherapy P Kanikarla-Marie, M Lam, AV Sorokin, MJ Overman, S Kopetz, ... Frontiers in Oncology 8, 107, 2018 | 31 | 2018 |
Role of hyperketonemia in inducing oxidative stress and cellular damage in cultured hepatocytes and type 1 diabetic rat liver P Kanikarla-Marie, SK Jain Cellular Physiology and Biochemistry 37 (6), 2160-2170, 2015 | 26 | 2015 |
l-Cysteine supplementation reduces high-glucose and ketone-induced adhesion of monocytes to endothelial cells by inhibiting ROS P Kanikarla-Marie, SK Jain Molecular and cellular biochemistry 391, 251-256, 2014 | 26 | 2014 |
Defining the KRAS-and ERK-dependent transcriptome in KRAS-mutant cancers JA Klomp, JE Klomp, CA Stalnecker, KL Bryant, AC Edwards, ... Science 384 (6700), eadk0775, 2024 | 25 | 2024 |
The provocative roles of platelets in liver disease and cancer P Kanikarla Marie, NW Fowlkes, V Afshar-Kharghan, SL Martch, ... Frontiers in Oncology 11, 643815, 2021 | 21 | 2021 |
Bioactive lipid metabolism in platelet “first responder” and cancer biology P Kanikarla-Marie, S Kopetz, ET Hawk, SW Millward, AK Sood, P Gresele, ... Cancer and Metastasis Reviews 37, 439-454, 2018 | 19 | 2018 |
Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells-implications from repressive chromatin organization and the role of ARTEMIS P Kanikarla-Marie, S Ronald, A De Benedetti BMC Research Notes 4, 1-7, 2011 | 14 | 2011 |
Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development JS Davis, P Kanikarla-Marie, M Gagea, PL Yu, D Fang, M Sebastian, ... BMC cancer 20, 1-10, 2020 | 13 | 2020 |