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Matthew Conrad Smith
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Features of protein–protein interactions that translate into potent inhibitors: topology, surface area and affinity
MC Smith, JE Gestwicki
Expert reviews in molecular medicine 14, 2012
3322012
The E3 Ubiquitin Ligase CHIP and the Molecular Chaperone Hsc70 Form a Dynamic, Tethered Complex
MC Smith, KM Scaglione, VA Assimon, S Patury, AD Thompson, ...
Biochemistry 52 (32), 5354-5364, 2013
702013
Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes
GM Walter, MC Smith, S Wisén, V Basrur, KSJ Elenitoba-Johnson, ...
Journal of Biological Chemistry 286 (47), 40486-40493, 2011
342011
Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction
CG Evans, MC Smith, JP Carolan, JE Gestwicki
Bioorganic & medicinal chemistry letters 21 (9), 2587-2590, 2011
222011
Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction
CG Evans, MC Smith, JP Carolan, JE Gestwicki
Bioorganic & medicinal chemistry letters 21 (9), 2587-2590, 2011
222011
High‐Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity
GM Walter, A Raveh, SA Mok, TJ McQuade, CJ Arevang, PJ Schultz, ...
Chemical biology & drug design 83 (4), 440-449, 2014
202014
Inhibiting Protein-Protein Interactions in the Hsp70 Complex as a Means to Regulate Protein Homeostasis
MC Smith
University of Michigan, 2012
12012
Spergualin analogs as inhibitors of Hsp70-CHIP protein-protein interactions
M Smith, V Assimon, CG Evans, JP Carolan, JE Gestwicki
The FASEB Journal 26 (1 Supplement), lb106-lb106, 2012
2012
Recent advances in medicinal chemistry
BSJ Blagg, DS Johnson, RM Garbaccio, CG Evans, MC Smith, ...
Bioorganic and Medicinal Chemistry Letters 21 (9), 2585, 2011
2011
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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