| Predicting prime editing efficiency and product purity by deep learning N Mathis, A Allam, L Kissling, KF Marquart, L Schmidheini, C Solari, ... Nature biotechnology 41 (8), 1151-1159, 2023 | 77 | 2023 |
| Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens KF Marquart, A Allam, S Janjuha, A Sintsova, L Villiger, N Frey, ... Nature communications 12 (1), 5114, 2021 | 67 | 2021 |
| miRNA engineering of CHO cells facilitates production of difficult‐to‐express proteins and increases success in cell line development S Fischer, KF Marquart, LA Pieper, J Fieder, M Gamer, I Gorr, P Schulz, ... Biotechnology and bioengineering 114 (7), 1495-1510, 2017 | 64 | 2017 |
| Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference K Xiong, KF Marquart, KJ la Cour Karottki, S Li, I Shamie, JS Lee, ... Biotechnology and bioengineering 116 (7), 1813-1819, 2019 | 51 | 2019 |
| Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing N Frey, L Tortola, D Egli, S Janjuha, T Rothgangl, KF Marquart, ... Nature communications 13 (1), 1804, 2022 | 35 | 2022 |
| Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis M Kleemann, J Bereuther, S Fischer, K Marquart, S Haenle, K Unger, ... Oncotarget 8 (12), 18773, 2016 | 25 | 2016 |
| Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility L Schmidheini, N Mathis, KF Marquart, T Rothgangl, L Kissling, D Böck, ... Nature Chemical Biology 20 (3), 333-343, 2024 | 20 | 2024 |
| Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope L Villiger, L Schmidheini, N Mathis, T Rothgangl, K Marquart, G Schwank Molecular Therapy-Nucleic Acids 26, 502-510, 2021 | 13 | 2021 |
| SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer P Simmler, C Cortijo, LM Koch, P Galliker, S Angori, HA Bolck, C Mueller, ... Cell Reports 40 (8), 2022 | 9 | 2022 |
| Mutant SF3B1 promotes malignancy in PDAC P Simmler, EI Ioannidi, T Mengis, KF Marquart, S Asawa, K Van-Lehmann, ... Elife 12, e80683, 2023 | 8 | 2023 |
| Enhancing prime editor activity by directed protein evolution in yeast Y Weber, D Böck, A Ivașcu, N Mathis, T Rothgangl, EI Ioannidi, AC Blaudt, ... Nature Communications 15 (1), 2092, 2024 | 7 | 2024 |
| Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs KF Marquart, N Mathis, A Mollaysa, S Müller, L Kissling, T Rothgangl, ... Nature Methods 21 (11), 2084-2093, 2024 | 2 | 2024 |
| Treatment of a genetic liver disease in mice through transient prime editor expression T Rothgangl, EI Ioannidi, Y Weber, A Tálas, D Böck, M Matsushita, ... bioRxiv, 2024.01. 22.575834, 2024 | 1 | 2024 |
| Research briefing G Schwank, KF Marquart Nature Methods 21, 1986-1987, 2024 | | 2024 |
| Effective Genome Editing with RNA-guided Systems optimized by Deep Learning KF Marquart ETH Zurich, 2024 | | 2024 |
| Safe delivery of AAV vectors to the liver of small weaned pigs by ultrasound-guided percutaneous transhepatic portal vein injection T Rothgangl, M Hruzova, R Gnannt, N Aeberhard, L Kissling, ... bioRxiv, 2023.04. 05.535660, 2023 | | 2023 |
| Mutant SF3B1 promotes malignancy in PDAC S Patrik, EI Ioannidi, M Tamara, KF Marquart, A Simran, K Van-Lehmann, ... eLife 12, 2023 | | 2023 |
| ANNEX III N Frey, L Tortola, D Egli, S Janjuha, KF Marquart, T Rothgangl, ... Investigating gastrointestinal cancers using various CRISPR screening …, 2021 | | 2021 |
| Overcoming treatment resistance in cisplatin-resistant ovarian carcinoma cells by tissue-specific miRNAs M Kleemann, J Bereuther, S Fischer, K Marquart, S Hänle, K Unger, ... Cancer Research 77 (13_Supplement), 2315-2315, 2017 | | 2017 |