Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications R Datta, TM Heaster, JT Sharick, AA Gillette, MC Skala Journal of biomedical optics 25 (7), 071203-071203, 2020 | 718 | 2020 |
3D microtumors in vitro supported by perfused vascular networks A Sobrino, DTT Phan, R Datta, X Wang, SJ Hachey, M Romero-López, ... Scientific reports 6 (1), 31589, 2016 | 399 | 2016 |
Fluorescence lifetime imaging of endogenous biomarker of oxidative stress R Datta, A Alfonso-García, R Cinco, E Gratton Scientific reports 5 (1), 9848, 2015 | 142 | 2015 |
Metabolic reprogramming in astrocytes distinguishes region-specific neuronal susceptibility in Huntington mice AA Polyzos, DY Lee, R Datta, M Hauser, H Budworth, A Holt, S Mihalik, ... Cell metabolism 29 (6), 1258-1273. e11, 2019 | 138 | 2019 |
Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy A Alfonso-García, TD Smith, R Datta, TU Luu, E Gratton, EO Potma, ... Journal of biomedical optics 21 (4), 046005-046005, 2016 | 75 | 2016 |
Metabolic changes associated with methionine stress sensitivity in MDA-MB-468 breast cancer cells SL Borrego, J Fahrmann, R Datta, C Stringari, D Grapov, M Zeller, Y Chen, ... Cancer & metabolism 4, 1-17, 2016 | 70 | 2016 |
Metabolic fingerprinting of bacteria by fluorescence lifetime imaging microscopy A Bhattacharjee, R Datta, E Gratton, AI Hochbaum Scientific reports 7 (1), 3743, 2017 | 58 | 2017 |
Recent innovations in fluorescence lifetime imaging microscopy for biology and medicine R Datta, A Gillette, M Stefely, MC Skala Journal of Biomedical Optics 26 (7), 070603-070603, 2021 | 56 | 2021 |
Label-free imaging of metabolism and oxidative stress in human induced pluripotent stem cell-derived cardiomyocytes R Datta, C Heylman, SC George, E Gratton Biomedical optics express 7 (5), 1690-1701, 2016 | 56 | 2016 |
Supervised machine learning for classification of the electrophysiological effects of chronotropic drugs on human induced pluripotent stem cell-derived cardiomyocytes C Heylman, R Datta, A Sobrino, S George, E Gratton PloS one 10 (12), e0144572, 2015 | 46 | 2015 |
Multicomponent analysis of phasor plot in a single pixel to calculate changes of metabolic trajectory in biological systems S Ranjit, R Datta, A Dvornikov, E Gratton The journal of physical chemistry A 123 (45), 9865-9873, 2019 | 43 | 2019 |
Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors R Datta, S Sivanand, AN Lau, LV Florek, AM Barbeau, J Wyckoff, ... Science Advances 8 (3), eabg6383, 2022 | 28 | 2022 |
Metabolic mapping of glioblastoma stem cells reveals NADH fluxes associated with glioblastoma phenotype and survival AB Schroeder, KB Pointer, PA Clark, R Datta, JS Kuo, KW Eliceiri Journal of biomedical optics 25 (3), 036502-036502, 2020 | 13 | 2020 |
Label-free fluorescence lifetime imaging microscopy (FLIM) to study metabolism and oxidative stress in biological systems R Datta University of California, Irvine, 2016 | 6 | 2016 |
Perspectives on label-free microscopy of heterogeneous and dynamic biological systems DL Pham, AA Gillette, J Riendeau, K Wiech, EC Guzman, R Datta, ... Journal of Biomedical Optics 29 (S2), S22702-S22702, 2025 | 4 | 2025 |
Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC AF Szymanska, C Heylman, R Datta, E Gratton, Z Nenadic Computers in biology and medicine 75, 109-117, 2016 | 4 | 2016 |
Advancement in OCT and image-processing techniques for automated ophthalmic diagnosis R Datta, S Aditya, DN Tibrewala 2010 IEEE Students Technology Symposium (TechSym), 26-33, 2010 | 3 | 2010 |
Superstable lipid vacuoles endow cartilage with its shape and biomechanics R Ramos, KT Pham, RC Prince, LB Leiser-Miller, MS Prasad, X Wang, ... Science 387 (6730), eads9960, 2025 | 2 | 2025 |
Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems R Datta, V Miskolci, GM Gallego-López, E Britt, A Gillette, A Kralovec, ... bioRxiv, 2024.07. 26.605362, 2024 | 2 | 2024 |
Cell division is coupled to the optical redox ratio (conference presentation) R Datta, Z Li, A Lau, M Vander Heiden, MC Skala Biophysics, Biology and Biophotonics III: the Crossroads 10504, 1050405, 2018 | 2 | 2018 |