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Prof. Dr. med. Christoph Kuppe, Ph.D.
Prof. Dr. med. Christoph Kuppe, Ph.D.
Emmy Noether Research Group Leader, RWTH Aachen University, Nephrology
Email verificata su ukaachen.de
Titolo
Citata da
Citata da
Anno
Decoding myofibroblast origins in human kidney fibrosis
C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ...
Nature 589 (7841), 281-286, 2021
5492021
Spatial multi-omic map of human myocardial infarction
C Kuppe, RO Ramirez Flores, Z Li, S Hayat, RT Levinson, X Liao, ...
Nature 608 (7924), 766-777, 2022
3792022
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease
R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ...
Cell stem cell 19 (5), 628-642, 2016
3212016
Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis
B Smeets, C Kuppe, EM Sicking, A Fuss, P Jirak, TH Van Kuppevelt, ...
Journal of the American Society of Nephrology 22 (7), 1262-1274, 2011
2522011
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell stem cell 29 (2), 217-231. e8, 2022
2142022
Chemokine Cxcl9 attenuates liver fibrosis‐associated angiogenesis in mice
H Sahin, E Borkham‐Kamphorst, C Kuppe, MM Zaldivar, C Grouls, ...
Hepatology 55 (5), 1610-1619, 2012
1572012
Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses
A Dugourd, C Kuppe, M Sciacovelli, E Gjerga, A Gabor, KB Emdal, ...
Molecular Systems Biology 17 (1), e9730, 2021
1372021
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner
K Hoeft, GJL Schaefer, H Kim, D Schumacher, T Bleckwehl, Q Long, ...
Cell Reports 42 (2), 2023
1262023
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
NB Leimkühler, HFE Gleitz, L Ronghui, IAM Snoeren, SNR Fuchs, ...
Cell stem cell 28 (4), 637-652. e8, 2021
1252021
The regenerative potential of parietal epithelial cells in adult mice
K Berger, K Schulte, P Boor, C Kuppe, TH van Kuppevelt, J Floege, ...
Journal of the American Society of Nephrology 25 (4), 693-705, 2014
1192014
Only hyperuricemia with crystalluria, but not asymptomatic hyperuricemia, drives progression of chronic kidney disease
M Sellmayr, MRH Petzsche, Q Ma, N Krüger, H Liapis, A Brink, B Lenz, ...
Journal of the American Society of Nephrology 31 (12), 2773-2792, 2020
1182020
Electrical forces determine glomerular permeability
R Hausmann, C Kuppe, H Egger, F Schweda, V Knecht, M Elger, ...
Journal of the American Society of Nephrology 21 (12), 2053-2058, 2010
892010
mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans
VG Puelles, JW Van Der Wolde, N Wanner, MW Scheppach, ...
JCI insight 4 (18), 2019
882019
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen
Z Li, C Kuppe, S Ziegler, M Cheng, N Kabgani, S Menzel, M Zenke, ...
Nature communications 12 (1), 6386, 2021
812021
Common histological patterns in glomerular epithelial cells in secondary focal segmental glomerulosclerosis
C Kuppe, HJ Gröne, T Ostendorf, TH Van Kuppevelt, P Boor, J Floege, ...
Kidney international 88 (5), 990-998, 2015
722015
A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models
F Ren, A Aliper, J Chen, H Zhao, S Rao, C Kuppe, IV Ozerov, M Zhang, ...
Nature Biotechnology, 1-13, 2024
712024
Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions
C Kuppe, K Leuchtle, A Wagner, N Kabgani, T Saritas, VG Puelles, ...
Kidney international 96 (1), 80-93, 2019
692019
Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin
N Kabgani, T Grigoleit, K Schulte, A Sechi, S Sauer-Lehnen, C Tag, ...
PloS one 7 (4), e34907, 2012
682012
Investigations of glucocorticoid action in GN
C Kuppe, C Van Roeyen, K Leuchtle, N Kabgani, M Vogt, ...
Journal of the American Society of Nephrology 28 (5), 1408-1420, 2017
642017
Mapping the cardiac vascular niche in heart failure
F Peisker, M Halder, J Nagai, S Ziegler, N Kaesler, K Hoeft, R Li, ...
Nature Communications 13 (1), 3027, 2022
602022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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