| Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model SA Tersey, Y Nishiki, AT Templin, SM Cabrera, ND Stull, SC Colvin, ... Diabetes 61 (4), 818-827, 2012 | 372 | 2012 |
| Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway M Hatanaka, B Maier, EK Sims, AT Templin, RN Kulkarni, C Evans-Molina, ... Diabetes 63 (10), 3404-3415, 2014 | 61 | 2014 |
| Insulin regulates carboxypeptidase E by modulating translation initiation scaffolding protein eIF4G1 in pancreatic β cells CW Liew, A Assmann, AT Templin, JC Raum, KL Lipson, S Rajan, ... Proceedings of the National Academy of Sciences 111 (22), E2319-E2328, 2014 | 51 | 2014 |
| The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets DT Meier, L Entrup, AT Templin, MF Hogan, M Mellati, S Zraika, RL Hull, ... Diabetologia 59 (10), 2166-2171, 2016 | 40 | 2016 |
| Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling AT Templin, B Maier, Y Nishiki, SA Tersey, RG Mirmira Cell Cycle 10 (7), 1043-1049, 2011 | 40 | 2011 |
| β-Cell death in diabetes: past discoveries, present understanding, and potential future advances N Mukherjee, L Lin, CJ Contreras, AT Templin Metabolites 11 (11), 796, 2021 | 37 | 2021 |
| Translational control of inducible nitric oxide synthase by p38 MAPK in islet β-cells Y Nishiki, A Adewola, M Hatanaka, AT Templin, B Maier, RG Mirmira Molecular endocrinology 27 (2), 336-349, 2013 | 31 | 2013 |
| Apoptosis repressor with caspase recruitment domain ameliorates amyloid-induced β-cell apoptosis and JNK pathway activation AT Templin, T Samarasekera, DT Meier, MF Hogan, M Mellati, MT Crow, ... Diabetes 66 (10), 2636-2645, 2017 | 27 | 2017 |
| Determination of optimal sample size for quantification of β-cell area, amyloid area and β-cell apoptosis in isolated islets DT Meier, L Entrup, AT Templin, MF Hogan, T Samarasekera, S Zraika, ... Journal of Histochemistry & Cytochemistry 63 (8), 663-673, 2015 | 21 | 2015 |
| Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response AT Templin, B Maier, SA Tersey, M Hatanaka, RG Mirmira Molecular Endocrinology 28 (11), 1820-1830, 2014 | 20 | 2014 |
| Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice JJ Castillo, AC Aplin, DJ Hackney, MF Hogan, N Esser, AT Templin, ... Diabetologia 65 (10), 1687-1700, 2022 | 18 | 2022 |
| Matrix metalloproteinase-9 protects islets from amyloid-induced toxicity DT Meier, LH Tu, S Zraika, MF Hogan, AT Templin, RL Hull, DP Raleigh, ... Journal of Biological Chemistry 290 (51), 30475-30485, 2015 | 18 | 2015 |
| Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro AT Templin, M Mellati, DT Meier, N Esser, MF Hogan, JJ Castillo, R Akter, ... Diabetologia 63, 2385-2395, 2020 | 17 | 2020 |
| RIPK1 and RIPK3 regulate TNFα-induced β-cell death in concert with caspase activity CJ Contreras, N Mukherjee, RCS Branco, L Lin, MF Hogan, EP Cai, ... Molecular Metabolism 65, 101582, 2022 | 16 | 2022 |
| Disease-associated astrocytes and microglia markers are upregulated in mice fed high fat diet L Lin, R Basu, D Chatterjee, AT Templin, JN Flak, TS Johnson Scientific Reports 13 (1), 12919, 2023 | 14 | 2023 |
| Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice AT Templin, M Mellati, R Soininen, MF Hogan, N Esser, JJ Castillo, ... Protein Engineering, Design and Selection 32 (2), 95-102, 2019 | 13 | 2019 |
| Inhibition of insulin-degrading enzyme does not increase islet amyloid deposition in vitro MF Hogan, DT Meier, S Zraika, AT Templin, M Mellati, RL Hull, ... Endocrinology 157 (9), 3462-3468, 2016 | 12 | 2016 |
| Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice AT Templin, DT Meier, JR Willard, T Wolden-Hanson, K Conway, YG Lin, ... Diabetologia 61, 2215-2224, 2018 | 11 | 2018 |
| RNA-seq-based identification of Star upregulation by islet amyloid formation MF Hogan, M Ziemann, H KN, H Rodriguez, A Kaspi, N Esser, AT Templin, ... Protein Engineering, Design and Selection 32 (2), 67-76, 2019 | 9 | 2019 |
| Probing the meaning of persistent propeptide release in type 1 diabetes SE Kahn, AT Templin, RL Hull, CB Verchere Diabetes Care 42 (2), 183, 2019 | 8 | 2019 |
Raghavendra MirmiraThe University of ChicagoEmail verificata su uchicago.edu