| Glypican-1 identifies cancer exosomes and detects early pancreatic cancer SA Melo, LB Luecke, C Kahlert, AF Fernandez, ST Gammon, J Kaye, ... Nature 523 (7559), 177-182, 2015 | 2939 | 2015 |
| Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer S Kamerkar, VS LeBleu, H Sugimoto, S Yang, CF Ruivo, SA Melo, JJ Lee, ... Nature 546 (7659), 498-503, 2017 | 2421 | 2017 |
| Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis SA Melo, H Sugimoto, JT O’Connell, N Kato, A Villanueva, A Vidal, L Qiu, ... Cancer cell 26 (5), 707-721, 2014 | 1719 | 2014 |
| Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer C Kahlert, SA Melo, A Protopopov, J Tang, S Seth, M Koch, J Zhang, ... Journal of Biological Chemistry 289 (7), 3869-3875, 2014 | 1141 | 2014 |
| eRNAs are required for p53-dependent enhancer activity and gene transcription CA Melo, J Drost, PJ Wijchers, H van de Werken, E de Wit, JAFO Vrielink, ... Molecular cell 49 (3), 524-535, 2013 | 584 | 2013 |
| The biology of cancer exosomes: insights and new perspectives CF Ruivo, B Adem, M Silva, SA Melo Cancer research 77 (23), 6480-6488, 2017 | 536 | 2017 |
| TGF-β1–containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis FT Borges, SA Melo, BC Özdemir, N Kato, I Revuelta, CA Miller, ... Journal of the American Society of Nephrology 24 (3), 385-392, 2013 | 477 | 2013 |
| A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells SA Melo, C Moutinho, S Ropero, GA Calin, S Rossi, R Spizzo, ... Cancer cell 18 (4), 303-315, 2010 | 461 | 2010 |
| Dysregulation of microRNAs in cancer: playing with fire SA Melo, M Esteller FEBS letters 585 (13), 2087-2099, 2011 | 442 | 2011 |
| The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer AF Fernandez, C Rosales, P Lopez-Nieva, O Graña, E Ballestar, ... Genome research 19 (3), 438-451, 2009 | 311 | 2009 |
| Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing S Melo, A Villanueva, C Moutinho, V Davalos, R Spizzo, C Ivan, S Rossi, ... Proceedings of the National Academy of Sciences 108 (11), 4394-4399, 2011 | 287 | 2011 |
| The fusion of two worlds: Non-coding RNAs and extracellular vesicles-diagnostic and therapeutic implications Y Sato-Kuwabara, SA Melo, FA Soares, GA Calin International journal of oncology 46 (1), 17-27, 2015 | 272 | 2015 |
| Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer S Yang, SPY Che, P Kurywchak, JL Tavormina, LB Gansmo, ... Cancer biology & therapy 18 (3), 158-165, 2017 | 257 | 2017 |
| CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer A Lujambio, A Portela, J Liz, SA Melo, S Rossi, R Spizzo, CM Croce, ... Oncogene 29 (48), 6390-6401, 2010 | 227 | 2010 |
| Exosomes and immune response in cancer: friends or foes? FM Barros, F Carneiro, JC Machado, SA Melo Frontiers in immunology 9, 730, 2018 | 225 | 2018 |
| Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA N Léveillé, CA Melo, K Rooijers, A Díaz-Lagares, SA Melo, G Korkmaz, ... Nature communications 6 (1), 6520, 2015 | 184 | 2015 |
| Blocking tumor-educated MSC paracrine activity halts osteosarcoma progression SR Baglio, T Lagerweij, M Pérez-Lanzón, XD Ho, N Léveillé, SA Melo, ... Clinical Cancer Research 23 (14), 3721-3733, 2017 | 178 | 2017 |
| Exosomes in cancer: Use them or target them? N Bastos, CF Ruivo, S da Silva, SA Melo Seminars in cell & developmental biology 78, 13-21, 2018 | 155 | 2018 |
| N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration I Rigoutsos, SK Lee, SY Nam, S Anfossi, B Pasculli, M Pichler, Y Jing, ... Genome biology 18, 1-21, 2017 | 107 | 2017 |
| Molecular pathways: microRNAs as cancer therapeutics SA Melo, R Kalluri Clinical cancer research 18 (16), 4234-4239, 2012 | 93 | 2012 |
