| Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes*♦ CF Sephton, C Cenik, A Kucukural, EB Dammer, B Cenik, YH Han, ... Journal of biological chemistry 286 (2), 1204-1215, 2011 | 515 | 2011 |
| TDP-43 is a developmentally regulated protein essential for early embryonic development CF Sephton, SK Good, S Atkin, CM Dewey, P Mayer, J Herz, G Yu Journal of Biological Chemistry 285 (9), 6826-6834, 2010 | 456 | 2010 |
| TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor CM Dewey, B Cenik, CF Sephton, DR Dries, P Mayer III, SK Good, ... Molecular and cellular biology 31 (5), 1098-1108, 2011 | 419 | 2011 |
| TDP-43 aggregation in neurodegeneration: are stress granules the key? CM Dewey, B Cenik, CF Sephton, BA Johnson, J Herz, G Yu Brain research 1462, 16-25, 2012 | 276 | 2012 |
| Progranulin: a proteolytically processed protein at the crossroads of inflammation and neurodegeneration B Cenik, CF Sephton, BK Cenik, J Herz, G Yu Journal of Biological Chemistry 287 (39), 32298-32306, 2012 | 228 | 2012 |
| Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia B Cenik, CF Sephton, CM Dewey, X Xian, S Wei, K Yu, W Niu, G Coppola, ... Journal of Biological Chemistry 286 (18), 16101-16108, 2011 | 174 | 2011 |
| Activity-dependent FUS dysregulation disrupts synaptic homeostasis CF Sephton, AA Tang, A Kulkarni, J West, M Brooks, JJ Stubblefield, Y Liu, ... Proceedings of the National Academy of Sciences 111 (44), E4769-E4778, 2014 | 164 | 2014 |
| The function of RNA-binding proteins at the synapse: implications for neurodegeneration CF Sephton, G Yu Cellular and Molecular Life Sciences 72, 3621-3635, 2015 | 127 | 2015 |
| Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD ME Ward, A Taubes, R Chen, BL Miller, CF Sephton, JM Gelfand, ... Journal of Experimental Medicine 211 (10), 1937-1945, 2014 | 121 | 2014 |
| TDP-43 in central nervous system development and function: clues to TDP-43-associated neurodegeneration CF Sephton, B Cenik, BK Cenik, J Herz, G Yu Biological chemistry 393 (7), 589-594, 2012 | 99 | 2012 |
| Metabolic networks influencing skeletal muscle fiber composition I Bourdeau Julien, CF Sephton, PA Dutchak Frontiers in cell and developmental biology 6, 125, 2018 | 77 | 2018 |
| FUS contributes to mTOR-dependent inhibition of translation M Sévigny, IB Julien, JP Venkatasubramani, JB Hui, PA Dutchak, ... Journal of Biological Chemistry 295 (52), 18459-18473, 2020 | 47 | 2020 |
| Chronic stress induces sex-specific functional and morphological alterations in corticoaccumbal and corticotegmental pathways TP Bittar, MC Pelaez, JCH Silva, F Quessy, AA Lavigne, D Morency, ... Biological Psychiatry 90 (3), 194-205, 2021 | 46 | 2021 |
| Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease PA Gelon, PA Dutchak, CF Sephton Frontiers in Molecular Neuroscience 15, 1000183, 2022 | 39 | 2022 |
| Haloperidol induces the nuclear translocation of phosphatidylinositol 3′-kinase to disrupt Akt phosphorylation in PC12 cells Y Dai, Z Wei, CF Sephton, D Zhang, DH Anderson, DD Mousseau Journal of Psychiatry and Neuroscience 32 (5), 323-330, 2007 | 36 | 2007 |
| The nuclear localization of 3'-phosphoinositide-dependent kinase-1 is dependent on its association with the protein tyrosine phosphatase SHP-1 CF Sephton, D Zhang, TM Lehmann, PR Pennington, MP Scheid, ... Cellular signalling 21 (11), 1634-1644, 2009 | 26 | 2009 |
| γ-Secretase-regulated proteolysis of the Notch receptor by mitochondrial intermediate peptidase SF Lee, B Srinivasan, CF Sephton, DR Dries, B Wang, C Yu, Y Wang, ... Journal of Biological Chemistry 286 (31), 27447-27453, 2011 | 23 | 2011 |
| Widespread alterations in microRNA biogenesis in human Huntington’s disease putamen S Petry, R Keraudren, B Nateghi, A Loiselle, K Pircs, J Jakobsson, ... Acta neuropathologica communications 10 (1), 106, 2022 | 18 | 2022 |
| NPRL2 inhibition of mTORC1 controls sodium channel expression and brain amino acid homeostasis JB Hui, JCH Silva, MC Pelaez, M Sévigny, JP Venkatasubramani, ... Eneuro 9 (2), 2022 | 8 | 2022 |
| hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated M Gagné, JE Deshaies, H Sidibé, Y Benchaar, D Arbour, A Dubinski, ... Frontiers in neuroscience 15, 724307, 2021 | 8 | 2021 |