Selective Sirt2 inhibition by ligand-induced rearrangement of the active site T Rumpf, M Schiedel, B Karaman, C Roessler, BJ North, A Lehotzky, ... Nature communications 6 (1), 6263, 2015 | 298 | 2015 |
Molecular modeling of potential anticancer agents from African medicinal plants F Ntie-Kang, JN Nwodo, A Ibezim, CV Simoben, B Karaman, VF Ngwa, ... Journal of chemical information and modeling 54 (9), 2433-2450, 2014 | 104 | 2014 |
Aminothiazoles as potent and selective Sirt2 inhibitors: a structure–activity relationship study M Schiedel, T Rumpf, B Karaman, A Lehotzky, J Oláh, S Gerhardt, J Ovádi, ... Journal of medicinal chemistry 59 (4), 1599-1612, 2016 | 99 | 2016 |
Computational drug repurposing: current trends B Karaman, W Sippl Current medicinal chemistry 26 (28), 5389-5409, 2019 | 93 | 2019 |
Elastin is heterogeneously cross-linked CU Schräder, A Heinz, P Majovsky, BK Mayack, J Brinckmann, W Sippl, ... Journal of Biological Chemistry 293 (39), 15107-15119, 2018 | 77 | 2018 |
Structure‐based development of an affinity probe for Sirtuin 2 M Schiedel, T Rumpf, B Karaman, A Lehotzky, S Gerhardt, J Ovádi, ... Angewandte Chemie International Edition 55 (6), 2252-2256, 2016 | 70 | 2016 |
Chromo-pharmacophores: photochromic diarylmaleimide inhibitors for sirtuins C Falenczyk, M Schiedel, B Karaman, T Rumpf, N Kuzmanovic, M Grøtli, ... Chemical Science 5 (12), 4794-4799, 2014 | 65 | 2014 |
Natural products as modulators of sirtuins B Karaman Mayack, W Sippl, F Ntie-Kang Molecules 25 (14), 3287, 2020 | 56 | 2020 |
Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants F Ntie-Kang, CV Simoben, B Karaman, VF Ngwa, PN Judson, W Sippl, ... Drug design, development and therapy, 2137-2154, 2016 | 37 | 2016 |
Increased potency and selectivity for group III metabotropic glutamate receptor agonists binding at dual sites C Selvam, IA Lemasson, I Brabet, N Oueslati, B Karaman, A Cabaye, ... Journal of medicinal chemistry 61 (5), 1969-1989, 2018 | 32 | 2018 |
Docking and binding free energy calculations of sirtuin inhibitors B Karaman, W Sippl European journal of medicinal chemistry 93, 584-598, 2015 | 32 | 2015 |
Identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing B Karaman, Z Alhalabi, S Swyter, SO Mihigo, K Andrae-Marobela, M Jung, ... Molecules 23 (2), 416, 2018 | 29 | 2018 |
Antibacterial, antitubercular and antiviral activity evaluations of some arylidenehydrazide derivatives bearing imidazo [2, 1-b] thiazole moiety NU Güzeldemirci, B Karaman, Ö Küçükbasmaci Turkish Journal of Pharmaceutical Sciences 14 (2), 157, 2017 | 29 | 2017 |
Fluorescence-Based Screening Assays for the NAD+-Dependent Histone Deacetylase smSirt2 from Schistosoma mansoni M Schiedel, M Marek, J Lancelot, B Karaman, I Almlöf, J Schultz, W Sippl, ... Journal of Biomolecular Screening 20 (1), 112-121, 2015 | 24 | 2015 |
Synthesis and biological evaluation of new imidazo[2,1-b]thiazole derivatives as anticancer agents B Karaman, N Ulusoy Güzeldemirci Medicinal Chemistry Research 25, 2471-2484, 2016 | 21 | 2016 |
Modeling disruption of Apis mellifera (honey bee) odorant‐binding protein function with high‐affinity binders BK Mayack Journal of Molecular Recognition 36 (5), e3008, 2023 | 8 | 2023 |
Structure-based design and computational studies of sirtuin inhibitors B Karaman, M Jung, W Sippl Epi-informatics, 297-325, 2016 | 8 | 2016 |
2-[6-(4-Chlorophenyl) imidazo [2, 1-b][1, 3] thiazol-2-yl]-N′-[(E)-4-methoxybenzylidene] acetohydrazide M Akkurt, NU Güzeldemirci, B Karaman, O Büyükgüngör Acta Crystallographica Section E: Structure Reports Online 67 (1), o184-o185, 2011 | 5 | 2011 |
Natural product epigenetic modulators and inhibitors F Ntie-Kang, B Karaman Mayack, S Valente, C Battistelli Frontiers in Pharmacology 12, 651395, 2021 | 4 | 2021 |
İmidazo [2, 1-b] tiyazol türevi heterosiklik bileşikler B Karaman İstanbul Üniversitesi Sağlık Bilimleri Enstitüsü Farmasötik Kimya AD Yüksek …, 2010 | 3 | 2010 |