Structure of the NS2B-NS3 protease from Zika virus after self-cleavage WW Phoo, Y Li, Z Zhang, MY Lee, YR Loh, YB Tan, EY Ng, J Lescar, ... Nature communications 7 (1), 13410, 2016 | 237 | 2016 |
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ... PLoS pathogens 11 (3), e1004682, 2015 | 237 | 2015 |
Crystal structure of unlinked NS2B-NS3 protease from Zika virus Z Zhang, Y Li, YR Loh, WW Phoo, AW Hung, CB Kang, D Luo Science 354 (6319), 1597-1600, 2016 | 195 | 2016 |
A subset of Kupffer cells regulates metabolism through the expression of CD36 C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ... Immunity 54 (9), 2101-2116. e6, 2021 | 161 | 2021 |
Structural dynamics of Zika virus NS2B-NS3 protease binding to dipeptide inhibitors Y Li, Z Zhang, WW Phoo, YR Loh, W Wang, S Liu, MW Chen, AW Hung, ... Structure 25 (8), 1242-1250. e3, 2017 | 118 | 2017 |
Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor Y Li, Z Zhang, WW Phoo, YR Loh, R Li, HY Yang, AE Jansson, J Hill, ... Structure 26 (4), 555-564. e3, 2018 | 90 | 2018 |
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication CMD Swarbrick, C Basavannacharya, KWK Chan, SA Chan, D Singh, ... Nucleic acids research 45 (22), 12904-12920, 2017 | 90 | 2017 |
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer DS Park, T Kozaki, SK Tiwari, M Moreira, A Khalilnezhad, F Torta, N Olivié, ... Nature 623 (7986), 397-405, 2023 | 83 | 2023 |
Functional interplay among the flavivirus NS3 protease, helicase, and cofactors K Li, WW Phoo, D Luo Virologica Sinica 29, 74-85, 2014 | 76 | 2014 |
Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors WW Phoo, Z Zhang, M Wirawan, EJC Chew, ABL Chew, J Kouretova, ... Antiviral research 160, 17-24, 2018 | 64 | 2018 |
Structural characterization of the linked NS 2B‐NS 3 protease of Zika virus Y Li, WW Phoo, YR Loh, Z Zhang, EY Ng, W Wang, TH Keller, D Luo, ... FEBS letters 591 (15), 2338-2347, 2017 | 42 | 2017 |
Therapeutics for flaviviral infections AM Bifani, KWK Chan, D Borrenberghs, MJA Tan, WW Phoo, S Watanabe, ... Antiviral Research 210, 105517, 2023 | 23 | 2023 |
Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 WW Phoo, A El Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ... Antiviral research 182, 104900, 2020 | 20 | 2020 |
Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches JP Quek, Z Ser, BLA Chew, X Li, L Wang, RM Sobota, D Luo, WW Phoo Viruses 14 (7), 1440, 2022 | 12 | 2022 |
Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein BLA Chew, AQ Ngoh, WW Phoo, KWK Chan, Z Ser, NK Tulsian, SS Lim, ... Elife 12, RP90762, 2024 | 11 | 2024 |
Structural basis of Zika virus NS1 multimerization and human antibody recognition BLA Chew, AQ Ngoh, WW Phoo, MJG Weng, HJ Sheng, KWK Chan, ... npj Viruses 2 (1), 14, 2024 | 3 | 2024 |
Structural basis of Zika virus NS1 multimerization and human antibody recognition D Luo, BLA Chew, AQ Ngoh, WW Phoo, MJG Weng, KWK Chan, YJ Tan, ... | 1 | 2023 |
A Broad-Spectrum Antiviral Targeting RNA Viruses. CP Gwee, T Felicetti, KWK Chan, S Alonso, MJA Tan, WW Phoo, ... Malaysian Journal of Medicine & Health Sciences 20, 2024 | | 2024 |
Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 upon binding to protease inhibitors WW Phoo, AE Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ... bioRxiv, 2020.01. 27.907089, 2020 | | 2020 |
Structural and biochemical characterization of non-structural protein 3 from flavivirus WW Phoo | | 2018 |