Segui
Wint Wint Phoo
Wint Wint Phoo
Duke-NUS, Johnson and Johnson Satellite Center for Global Health Discovery
Email verificata su duke-nus.edu.sg
Titolo
Citata da
Citata da
Anno
Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
WW Phoo, Y Li, Z Zhang, MY Lee, YR Loh, YB Tan, EY Ng, J Lescar, ...
Nature communications 7 (1), 13410, 2016
2372016
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication
Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ...
PLoS pathogens 11 (3), e1004682, 2015
2372015
Crystal structure of unlinked NS2B-NS3 protease from Zika virus
Z Zhang, Y Li, YR Loh, WW Phoo, AW Hung, CB Kang, D Luo
Science 354 (6319), 1597-1600, 2016
1952016
A subset of Kupffer cells regulates metabolism through the expression of CD36
C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ...
Immunity 54 (9), 2101-2116. e6, 2021
1612021
Structural dynamics of Zika virus NS2B-NS3 protease binding to dipeptide inhibitors
Y Li, Z Zhang, WW Phoo, YR Loh, W Wang, S Liu, MW Chen, AW Hung, ...
Structure 25 (8), 1242-1250. e3, 2017
1182017
Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor
Y Li, Z Zhang, WW Phoo, YR Loh, R Li, HY Yang, AE Jansson, J Hill, ...
Structure 26 (4), 555-564. e3, 2018
902018
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication
CMD Swarbrick, C Basavannacharya, KWK Chan, SA Chan, D Singh, ...
Nucleic acids research 45 (22), 12904-12920, 2017
902017
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
DS Park, T Kozaki, SK Tiwari, M Moreira, A Khalilnezhad, F Torta, N Olivié, ...
Nature 623 (7986), 397-405, 2023
832023
Functional interplay among the flavivirus NS3 protease, helicase, and cofactors
K Li, WW Phoo, D Luo
Virologica Sinica 29, 74-85, 2014
762014
Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors
WW Phoo, Z Zhang, M Wirawan, EJC Chew, ABL Chew, J Kouretova, ...
Antiviral research 160, 17-24, 2018
642018
Structural characterization of the linked NS 2B‐NS 3 protease of Zika virus
Y Li, WW Phoo, YR Loh, Z Zhang, EY Ng, W Wang, TH Keller, D Luo, ...
FEBS letters 591 (15), 2338-2347, 2017
422017
Therapeutics for flaviviral infections
AM Bifani, KWK Chan, D Borrenberghs, MJA Tan, WW Phoo, S Watanabe, ...
Antiviral Research 210, 105517, 2023
232023
Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3
WW Phoo, A El Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ...
Antiviral research 182, 104900, 2020
202020
Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches
JP Quek, Z Ser, BLA Chew, X Li, L Wang, RM Sobota, D Luo, WW Phoo
Viruses 14 (7), 1440, 2022
122022
Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein
BLA Chew, AQ Ngoh, WW Phoo, KWK Chan, Z Ser, NK Tulsian, SS Lim, ...
Elife 12, RP90762, 2024
112024
Structural basis of Zika virus NS1 multimerization and human antibody recognition
BLA Chew, AQ Ngoh, WW Phoo, MJG Weng, HJ Sheng, KWK Chan, ...
npj Viruses 2 (1), 14, 2024
32024
Structural basis of Zika virus NS1 multimerization and human antibody recognition
D Luo, BLA Chew, AQ Ngoh, WW Phoo, MJG Weng, KWK Chan, YJ Tan, ...
12023
A Broad-Spectrum Antiviral Targeting RNA Viruses.
CP Gwee, T Felicetti, KWK Chan, S Alonso, MJA Tan, WW Phoo, ...
Malaysian Journal of Medicine & Health Sciences 20, 2024
2024
Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3 upon binding to protease inhibitors
WW Phoo, AE Sahili, ZZ Zhang, MW Chen, CW Liew, J Lescar, ...
bioRxiv, 2020.01. 27.907089, 2020
2020
Structural and biochemical characterization of non-structural protein 3 from flavivirus
WW Phoo
2018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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