Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β cell dysfunction, and type 2 diabetes CY Zhang, G Baffy, P Perret, S Krauss, O Peroni, D Grujic, T Hagen, ... Cell 105 (6), 745-755, 2001 | 1228 | 2001 |
Health benefits of a pedometer-based physical activity intervention in sedentary workers CB Chan, DAJ Ryan, C Tudor-Locke Preventive medicine 39 (6), 1215-1222, 2004 | 563 | 2004 |
Increased uncoupling protein-2 levels in β-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action CB Chan, D De Leo, JW Joseph, TS McQuaid, XF Ha, F Xu, RG Tsushima, ... Diabetes 50 (6), 1302-1310, 2001 | 494 | 2001 |
Role of mitochondria in toxic oxidative stress MW Fariss, CB Chan, M Patel, B Van Houten, S Orrenius Molecular interventions 5 (2), 94, 2005 | 466 | 2005 |
Assessing the effects of weather conditions on physical activity participation using objective measures CB Chan, DA Ryan International journal of environmental research and public health 6 (10 …, 2009 | 367 | 2009 |
Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets. CB Chan, PE MacDonald, MC Saleh, DC Johns, E Marbàn, MB Wheeler Diabetes 48 (7), 1482-1486, 1999 | 340 | 1999 |
Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet JW Joseph, V Koshkin, CY Zhang, J Wang, BB Lowell, CB Chan, ... Diabetes 51 (11), 3211-3219, 2002 | 311 | 2002 |
Free fatty acid-induced β-cell defects are dependent on uncoupling protein 2 expression JW Joseph, V Koshkin, MC Saleh, WI Sivitz, CY Zhang, BB Lowell, ... Journal of Biological Chemistry 279 (49), 51049-51056, 2004 | 296 | 2004 |
Nutrition therapy JL Sievenpiper, CB Chan, PD Dworatzek, C Freeze, SL Williams, ... Canadian journal of diabetes 42, S64-S79, 2018 | 276 | 2018 |
Relationship between objective measures of physical activity and weather: a longitudinal study CB Chan, DAJ Ryan, C Tudor-Locke International Journal of Behavioral Nutrition and Physical Activity 3, 1-9, 2006 | 264 | 2006 |
Reactive oxygen species and endothelial function in diabetes Z Fatehi-Hassanabad, CB Chan, BL Furman European journal of pharmacology 636 (1-3), 8-17, 2010 | 231 | 2010 |
Inhibition of Kv2. 1 voltage-dependent K+ channels in pancreatic β-cells enhances glucose-dependent insulin secretion PE MacDonald, S Sewing, J Wang, JW Joseph, SR Smukler, ... Journal of Biological Chemistry 277 (47), 44938-44945, 2002 | 219 | 2002 |
The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor PK Leung, KBS Chow, PN Lau, KM Chu, CB Chan, CHK Cheng, H Wise Cellular signalling 19 (5), 1011-1022, 2007 | 216 | 2007 |
Uncoupling protein 2 and islet function CB Chan, MC Saleh, V Koshkin, MB Wheeler Diabetes 53 (suppl_1), S136-S142, 2004 | 216 | 2004 |
Cross‐sectional relationship of pedometer‐determined ambulatory activity to indicators of health CB Chan, E Spangler, J Valcour, C Tudor‐Locke Obesity Research 11 (12), 1563-1570, 2003 | 207 | 2003 |
Mitochondrial functional state in clonal pancreatic β-cells exposed to free fatty acids V Koshkin, X Wang, PE Scherer, CB Chan, MB Wheeler Journal of Biological Chemistry 278 (22), 19709-19715, 2003 | 160 | 2003 |
Uncoupling protein-2: evidence for its function as a metabolic regulator MC Saleh, MB Wheeler, CB Chan Diabetologia 45, 174-187, 2002 | 149 | 2002 |
BMI-referenced cut points for pedometer-determined steps per day in adults C Tudor-Locke, DR Bassett, WJ Rutherford, BE Ainsworth, CB Chan, ... Journal of Physical Activity and Health 5 (s1), S126-S139, 2008 | 136 | 2008 |
Barriers and mitigating strategies to healthcare access in indigenous communities of Canada: a narrative review NH Nguyen, FB Subhan, K Williams, CB Chan Healthcare 8 (2), 112, 2020 | 133 | 2020 |
Gene and protein kinase expression profiling of reactive oxygen species-associated lipotoxicity in the pancreatic β-cell line MIN6 X Wang, H Li, D De Leo, W Guo, V Koshkin, IG Fantus, A Giacca, ... Diabetes 53 (1), 129-140, 2004 | 126 | 2004 |