| Coumarins as modulators of the Keap1/Nrf2/ARE signaling pathway EHM Hassanein, AM Sayed, OE Hussein, AM Mahmoud Oxidative Medicine and Cellular Longevity 2020 (1), 1675957, 2020 | 197 | 2020 |
| Engineering of serine protease for improved thermostability and catalytic activity using rational design NM Ashraf, A Krishnagopal, A Hussain, D Kastner, AMM Sayed, YK Mok, ... International journal of biological macromolecules 126, 229-237, 2019 | 74 | 2019 |
| Flavonoids-mediated SIRT1 signaling activation in hepatic disorders AM Sayed, EHM Hassanein, SH Salem, OE Hussein, AM Mahmoud Life sciences 259, 118173, 2020 | 53 | 2020 |
| Edaravone and acetovanillone upregulate Nrf2 and PI3K/Akt/mTOR signaling and prevent cyclophosphamide cardiotoxicity in rats EHM Hassanein, OAM Abd El-Ghafar, MA Ahmed, AM Sayed, ... Drug Design, Development and Therapy, 5275-5288, 2020 | 45 | 2020 |
| Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity FEM Ali, AM Sayed, AH El-Bahrawy, ZMM Omar, EHM Hassanein Life Sciences 275, 119349, 2021 | 40 | 2021 |
| The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view EHM Hassanein, WR Mohamed, OS Ahmed, MM Abdel-Daim, AM Sayed Life sciences 308, 120971, 2022 | 34 | 2022 |
| Acetovanillone prevents cyclophosphamide‐induced acute lung injury by modulating PI3K/Akt/mTOR and Nrf2 signaling in rats OAM Abd El‐Ghafar, EHM Hassanein, AM Sayed, EK Rashwan, ... Phytotherapy Research, 2021 | 32 | 2021 |
| Regulation of Keap-1/Nrf2/AKT and iNOS/NF-κB/TLR4 signals by apocynin abrogated methotrexate-induced testicular toxicity: Mechanistic insights and computational pharmacological … AM Sayed, EHM Hassanein, FEM Ali, ZMM Omar, EK Rashwan, ... Life sciences 284, 119911, 2021 | 30 | 2021 |
| Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: Role of TLR4/NF-κB and c-Fos/c-Jun pro-inflammatory … AM Sayed, MM Abdel-Fattah, HH Arab, WR Mohamed, EHM Hassanein Chemico-Biological Interactions 351, 109732, 2022 | 28 | 2022 |
| Synthesis of novel biocompatible thienopyrimidine chromophores with aggregation-induced emission sensitive to molecular aggregation M Ahmed, O Younis, EA Orabi, AM Sayed, AM Kamal El-Dean, ... ACS omega 5 (46), 29988-30000, 2020 | 27 | 2020 |
| Hepatoprotective effect of acetovanillone against methotrexate hepatotoxicity: Role of Keap‐1/Nrf2/ARE, IL6/STAT‐3, and NF‐κB/AP‐1 signaling pathways OAM Abd El‐Ghafar, EHM Hassanein, FEM Ali, ZMM Omar, EK Rashwan, ... Phytotherapy Research, 2021 | 24 | 2021 |
| Design, synthesis, biological evaluation, and molecular docking of some new Thieno [2, 3-d] pyrimidine derivatives MS Tolba, AM Sayed, M Sayed, M Ahmed Journal of Molecular Structure 1246, 131179, 2021 | 23 | 2021 |
| The promising therapeutic potentials of ginsenosides mediated through p38 MAPK signaling inhibition ESA Arafa, MS Refaey, OAM Abd El-Ghafar, EHM Hassanein, AM Sayed Heliyon 7 (11), 2021 | 23 | 2021 |
| Ameliorate impacts of scopoletin against vancomycin-induced intoxication in rat model through modulation of Keap1-Nrf2/HO-1 and IκBα-P65 NF-κB/P38 MAPK signaling pathways … MM Khalaf, SM Hassan, AM Sayed, AM Abo-Youssef International Immunopharmacology 102, 108382, 2022 | 22 | 2022 |
| Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence AGS Shalkami, EHM Hassanein, AM Sayed, WR Mohamed, MM Khalaf, ... Environmental Science and Pollution Research 28, 67593-67607, 2021 | 18 | 2021 |
| Canagliflozin ameliorates ulcerative colitis via regulation of TLR4/MAPK/NF-κB and Nrf2/PPAR-γ/SIRT1 signaling pathways HS Althagafy, FEM Ali, EHM Hassanein, ZM Mohammedsaleh, ... European Journal of Pharmacology 960, 176166, 2023 | 15 | 2023 |
| Diallyl disulfide ameliorates methotrexate‐induced nephropathy in rats: Molecular studies and network pharmacology analysis EHM Hassanein, WR Mohamed, MM Khalaf, AGS Shalkami, AM Sayed, ... Journal of Food Biochemistry 45 (6), e13765, 2021 | 15 | 2021 |
| Prolyl isomerization of the CENP-A N-terminus regulates centromeric integrity in fission yeast HL Tan, KK Lim, Q Yang, JS Fan, AMM Sayed, LS Low, B Ren, TK Lim, ... Nucleic Acids Research 46 (3), 1167-1179, 2018 | 15 | 2018 |
| Apocynin abrogates methotrexate-induced nephrotoxicity: role of TLR4/NF-κB-p65/p38-MAPK, IL-6/STAT-3, PPAR-γ, and SIRT1/FOXO3 signaling pathways EHM Hassanein, AM Sayed, OAMA El-Ghafar, ZMM Omar, EK Rashwan, ... Archives of Pharmacal Research 46 (4), 339-359, 2023 | 14 | 2023 |
| Apocynin and its chitosan nanoparticles attenuated cisplatin-induced multiorgan failure: Synthesis, characterization, and biological evaluation NA Mahmoud, EHM Hassanein, EA Bakhite, ES Shaltout, AM Sayed Life Sciences 314, 121313, 2023 | 14 | 2023 |
Emad H.M. HassaneinAssociate Professor of Pharmacology & Toxicology - Faculty of Pharmacy Al-Azhar UniversityEmail verificata su azhar.edu.eg
