Effect of subcutaneous dupilumab on nasal polyp burden in patients with chronic sinusitis and nasal polyposis: a randomized clinical trial C Bachert, L Mannent, RM Naclerio, J Mullol, BJ Ferguson, P Gevaert, ... Jama 315 (5), 469-479, 2016 | 877 | 2016 |
Targeting key proximal drivers of type 2 inflammation in disease NA Gandhi, BL Bennett, NMH Graham, G Pirozzi, N Stahl, ... Nature reviews Drug discovery 15 (1), 35-50, 2016 | 795 | 2016 |
Commonality of the IL-4/IL-13 pathway in atopic diseases NA Gandhi, G Pirozzi, NMH Graham Expert review of clinical immunology 13 (5), 425-437, 2017 | 516 | 2017 |
Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement JM Orengo, AR Radin, V Kamat, A Badithe, LH Ben, BL Bennett, S Zhong, ... Nature communications 9 (1), 1421, 2018 | 232 | 2018 |
Methods for treating or preventing asthma by administering an il-4r antagonist M Ardeleanu, NA Gandhi, N Graham, SC Kirkesseli, S Kundu, E Ross, ... US Patent 9,574,004, 2017 | 50 | 2017 |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R inhibitor N Stahl, JM Orengo, AJ Murphy, N Gandhi, N Graham US Patent 10,392,439, 2019 | 42 | 2019 |
Methods for treating nasal polyposis by administering an IL-4R antagonist L Mannent, G Pirozzi, A Radin, NA Gandhi, R Evans US Patent 10,059,771, 2018 | 23 | 2018 |
Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist L Mannent, G Pirozzi, B Swanson, A Radin, NA Gandhi, R Evans, ... US Patent 10,066,017, 2018 | 19 | 2018 |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an antibody to IL-4 receptor N Stahl, JM Orengo, AJ Murphy, N Gandhi, N Graham US Patent 10,669,341, 2020 | 17 | 2020 |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an antibody to IL-4 receptor N Stahl, JM Orengo, AJ Murphy, N Gandhi, N Graham US Patent 10,676,530, 2020 | 16 | 2020 |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R inhibitor N Stahl, JM Orengo, AJ Murphy, N Gandhi, N Graham US Patent 11,485,788, 2022 | 10 | 2022 |
Dupilumab in chronic sinusitis with nasal polyposis, with and without asthma C Bachert, L Mannent, RM Naclerio, J Mullol, BJ Ferguson, L Jiao, ... Congress of the European Academy of Allergy and Clinical Immunology 70 …, 2015 | 8 | 2015 |
HMBD-002 is a novel, neutralizing, anti-VISTA antibody exhibiting strong preclinical efficacy and safety, being developed as a monotherapy and in combination with pembrolizumab. L DiMascio, D Thakkar, N Gandhi, S Guan, EK Rowinsky, P Ingram, ... Journal of Clinical Oncology 39 (15_suppl), e14569-e14569, 2021 | 6 | 2021 |
Abstract P197: An anti-HER3 antibody, HMBD-001, that uniquely binds to and blocks the HER3 heterodimerization interface, shows superior tumor growth inhibition in biomarker … D Thakkar, S Paliwal, S Kar, N Gandhi, K Paszkiewicz, P Ingram, ... Molecular Cancer Therapeutics 20 (12_Supplement), P197-P197, 2021 | 5 | 2021 |
Methods for treating nasal polyposis by administering an il-4r antagonist L Mannent, G Pirozzi, A Radin, NA Gandhi, R Evans US Patent App. 16/038,816, 2019 | 3 | 2019 |
Methods for treating chronic sinusitis with nasal polyps by administering an IL-4R antagonist L Mannent, G Pirozzi, B Swanson, A Radin, NA Gandhi, R Evans, ... US Patent 11,214,621, 2022 | 2 | 2022 |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an il-4r inhibitor N Stahl, JM Orengo, AJ Murphy, N GANDHI, N Graham US Patent App. 17/935,003, 2023 | 1 | 2023 |
Anti-HER3 antibody, HMBD-001, in combination with an EGFR inhibitor effectively inhibits tumor growth in biomarker selected pre-clinical models of squamous cell carcinomas W Toy, D Thakkar, K Luu, BNL Chi, J Lai, D Ray, N Gandhi, A Mas, ... Cancer Research 83 (7_Supplement), 2659-2659, 2023 | 1 | 2023 |
Methods for treating chronic sinusitis with nasal polyps by administering an il-4r antagonist L Mannent, G Pirozzi, B Swanson, A Radin, NA Gandhi, R Evans, ... US Patent App. 17/534,106, 2022 | 1 | 2022 |
Method of treating an allergy with allergen-specific monoclonal antibodies JM Orengo, NA Gandhi, A Radin, A Kostic, AJ Murphy, GD Yancopoulos US Patent 11,352,417, 2022 | 1 | 2022 |