Global analysis of fungal morphology exposes mechanisms of host cell escape TR O’Meara, AO Veri, T Ketela, B Jiang, T Roemer, LE Cowen Nature communications 6 (1), 6741, 2015 | 241 | 2015 |
Phenotypic and interaction profiling of the human phosphatases identifies diverse mitotic regulators N St-Denis, GD Gupta, ZY Lin, B Gonzalez-Badillo, AO Veri, JDR Knight, ... Cell reports 17 (9), 2488-2501, 2016 | 113 | 2016 |
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase J MacAlpine, M Daniel-Ivad, Z Liu, J Yano, NM Revie, RT Todd, ... Nature communications 12 (1), 6151, 2021 | 95 | 2021 |
Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets C Fu, X Zhang, AO Veri, KR Iyer, E Lash, A Xue, H Yan, NM Revie, ... Nature communications 12 (1), 6497, 2021 | 69 | 2021 |
High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis TR O’Meara, K Duah, CX Guo, ME Maxson, RG Gaudet, K Koselny, ... MBio 9 (4), 10.1128/mbio. 01581-18, 2018 | 68 | 2018 |
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space AO Veri, Z Miao, RS Shapiro, F Tebbji, TR O’Meara, SH Kim, J Colazo, ... PLoS genetics 14 (3), e1007270, 2018 | 55 | 2018 |
Metal chelation as a powerful strategy to probe cellular circuitry governing fungal drug resistance and morphogenesis EJ Polvi, AF Averette, SC Lee, T Kim, YS Bahn, AO Veri, N Robbins, ... PLoS genetics 12 (10), e1006350, 2016 | 51 | 2016 |
Mapping the Hsp90 genetic network reveals ergosterol biosynthesis and phosphatidylinositol-4-kinase signaling as core circuitry governing cellular stress TR O’Meara, AO Veri, EJ Polvi, X Li, SF Valaei, S Diezmann, LE Cowen PLoS Genetics 12 (6), e1006142, 2016 | 51 | 2016 |
Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a … TR O’Meara, MJ O’Meara, EJ Polvi, MR Pourhaghighi, SD Liston, ZY Lin, ... PLoS biology 17 (7), e3000358, 2019 | 48 | 2019 |
Progress and prospects for targeting Hsp90 to treat fungal infections A Veri, LE Cowen Parasitology 141 (9), 1127-1137, 2014 | 48 | 2014 |
Regulation of the heat shock transcription factor Hsf1 in fungi: implications for temperature-dependent virulence traits AO Veri, N Robbins, LE Cowen FEMS yeast research 18 (5), foy041, 2018 | 30 | 2018 |
Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1–Hsp90 pathway G Guan, L Tao, H Yue, W Liang, J Gong, J Bing, Q Zheng, AO Veri, S Fan, ... PLoS Biology 17 (3), e2006966, 2019 | 27 | 2019 |
Functional connections between cell cycle and proteostasis in the regulation of Candida albicans morphogenesis S Hossain, E Lash, AO Veri, LE Cowen Cell reports 34 (8), 2021 | 26 | 2021 |
Structure-guided approaches to targeting stress responses in human fungal pathogens EV LeBlanc, EJ Polvi, AO Veri, GG Privé, LE Cowen Journal of Biological Chemistry 295 (42), 14458-14472, 2020 | 24 | 2020 |
Mitochondrial perturbation reduces susceptibility to xenobiotics through altered efflux in Candida albicans S Hossain, AO Veri, Z Liu, KR Iyer, TR O’Meara, N Robbins, LE Cowen Genetics 219 (2), iyab095, 2021 | 21 | 2021 |
The proteasome governs fungal morphogenesis via functional connections with Hsp90 and cAMP-protein kinase a signaling S Hossain, AO Veri, LE Cowen MBio 11 (2), 10.1128/mbio. 00290-20, 2020 | 21 | 2020 |
Functional divergence of a global regulatory complex governing fungal filamentation EJ Polvi, AO Veri, Z Liu, S Hossain, S Hyde, SH Kim, F Tebbji, A Sellam, ... PLoS genetics 15 (1), e1007901, 2019 | 21 | 2019 |
The macrophage-derived protein PTMA induces filamentation of the human fungal pathogen Candida albicans NT Case, K Duah, B Larsen, CJ Wong, AC Gingras, TR O’Meara, ... Cell reports 36 (8), 2021 | 16 | 2021 |
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase. Nat Commun 12: 6151 J MacAlpine, M Daniel-Ivad, Z Liu, J Yano, NM Revie, RT Todd, ... | 12 | 2021 |
Global analysis of fungal morphology exposes mechanisms of host cell escape. Nat Commun. 2015; 6: 6741 TR O’Meara, AO Veri, T Ketela, B Jiang, T Roemer, LE Cowen Epub 2015/04/01. https://doi. org/10.1038/ncomms7741 PMID: 25824284, 0 | 8 | |