| Interleukin-6 and its receptors: a highly regulated and dynamic system J Wolf, S Rose-John, C Garbers Cytokine 70 (1), 11-20, 2014 | 724 | 2014 |
| Interleukin-6: designing specific therapeutics for a complex cytokine C Garbers, S Heink, T Korn, S Rose-John Nature Reviews Drug Discovery 17 (6), 395-412, 2018 | 614 | 2018 |
| ADAM17: a molecular switch to control inflammation and tissue regeneration J Scheller, A Chalaris, C Garbers, S Rose-John Trends in immunology 32 (8), 380-387, 2011 | 592 | 2011 |
| The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition C Garbers, S Aparicio-Siegmund, S Rose-John Current Opinion in Immunology 34, 75-82, 2015 | 467 | 2015 |
| Plasticity and cross-talk of Interleukin 6-type cytokines C Garbers, HM Hermanns, F Schaper, G Müller-Newen, J Grötzinger, ... Cytokine & Growth Factor Reviews, 2012 | 444 | 2012 |
| Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH 17 cells S Heink, N Yogev, C Garbers, M Herwerth, L Aly, C Gasperi, V Husterer, ... Nature immunology 18 (1), 74-85, 2017 | 415 | 2017 |
| Interleukin-6: From basic biology to selective blockade of pro-inflammatory activities J Scheller, C Garbers, S Rose-John Seminars in immunology 26 (1), 2-12, 2014 | 379 | 2014 |
| The soluble Interleukin 6 receptor: generation and role in inflammation and cancer A Chalaris, C Garbers, B Rabe, S Rose-John, J Scheller European journal of cell biology 90 (6), 484-494, 2011 | 375 | 2011 |
| Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding C Garbers, N Jänner, A Chalaris, ML Moss, DM Floss, D Meyer, ... Journal of Biological Chemistry 286 (17), 14804, 2011 | 241 | 2011 |
| Targeting IL-6 trans-signalling: past, present and future prospects S Rose-John, BJ Jenkins, C Garbers, JM Moll, J Scheller Nature Reviews Immunology 23 (10), 666-681, 2023 | 215 | 2023 |
| Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor C Garbers, W Thaiss, GW Jones, GH Waetzig, I Lorenzen, F Guilhot, ... Journal of Biological Chemistry 286 (50), 42959-42970, 2011 | 201 | 2011 |
| Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease S Schreiber, K Aden, JP Bernardes, C Conrad, F Tran, H Höper, V Volk, ... Gastroenterology 160 (7), 2354-2366. e11, 2021 | 200 | 2021 |
| Interleukin-6 and interleukin-11: same same but different C Garbers, J Scheller Biological chemistry 394 (9), 1145-1161, 2013 | 170 | 2013 |
| The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases C Garbers, N Monhasery, S Aparicio-Siegmund, J Lokau, P Baran, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (9 …, 2014 | 159 | 2014 |
| Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to … N Schumacher, D Meyer, A Mauermann, J von der Heyde, J Wolf, ... Journal of Biological Chemistry 290 (43), 26059-26071, 2015 | 154 | 2015 |
| A Disintegrin and Metalloprotease (ADAM) 10 and ADAM17 Are Major Sheddases of T Cell Immunoglobulin and Mucin Domain 3 (Tim-3) K Möller-Hackbarth, C Dewitz, O Schweigert, A Trad, C Garbers, ... Journal of Biological Chemistry 288 (48), 34529-34544, 2013 | 150 | 2013 |
| Control of ADAM17 activity by regulation of its cellular localisation I Lorenzen, J Lokau, Y Korpys, M Oldefest, CM Flynn, U Künzel, ... Scientific Reports 6, 35067, 2016 | 138 | 2016 |
| An interleukin-6 receptor-dependent molecular switch mediates signal transduction of the IL-27 cytokine subunit p28 (IL-30) via a gp130 receptor homodimer C Garbers, B Spudy, S Aparicio-Siegmund, GH Waetzig, J Sommer, ... Journal of Biological Chemistry, 2012 | 137 | 2012 |
| Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation S Riethmueller, P Somasundaram, JC Ehlers, CW Hung, CM Flynn, ... PLoS biology 15 (1), e2000080, 2017 | 135 | 2017 |
| Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment. CM Wunderlich, PJ Ackermann, AL Ostermann, P Adams-Quack, MC Vogt, ... Nature communications 9 (1), 1646-1646, 2018 | 134 | 2018 |
Stefan Rose-JohnUniversity of KielEmail verificata su biochem.uni-kiel.de
