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Eszter Németh
Eszter Németh
Research Centre for Natural Sciences, Budapest
Email verificata su ttk.hu
Titolo
Citata da
Citata da
Anno
Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
Á Póti, H Gyergyák, E Németh, O Rusz, S Tóth, C Kovácsházi, D Chen, ...
Genome biology 20, 1-13, 2019
1072019
Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers
RA DeWeerd, E Németh, Á Póti, N Petryk, CL Chen, O Hyrien, D Szüts, ...
Cell reports 38 (12), 2022
412022
BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1
D Chen, JZ Gervai, Á Póti, E Németh, Z Szeltner, B Szikriszt, Z Gyüre, ...
Nature communications 13 (1), 226, 2022
332022
A comparative analysis of the mutagenicity of platinum-containing chemotherapeutic agents reveals direct and indirect mutagenic mechanisms
B Szikriszt, Á Póti, E Németh, N Kanu, C Swanton, D Szüts
Mutagenesis 36 (1), 75-86, 2021
292021
Two main mutational processes operate in the absence of DNA mismatch repair
E Németh, A Lovrics, JZ Gervai, M Seki, G Rospo, A Bardelli, D Szüts
DNA repair 89, 102827, 2020
252020
Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells
D Kovacsics, A Brózik, B Tihanyi, Z Matula, A Borsy, N Mészáros, E Szabó, ...
Biochemical Pharmacology 175, 113865, 2020
212020
The role of the N-terminal loop in the function of the colicin E7 nuclease domain
A Czene, E Németh, IG Zóka, NI Jakab-Simon, T Körtvélyesi, K Nagata, ...
JBIC Journal of Biological Inorganic Chemistry 18, 309-321, 2013
202013
Fine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N‐terminal mutations
E Németh, T Körtvélyesi, PW Thulstrup, HEM Christensen, M Kožíšek, ...
Protein Science 23 (8), 1113-1122, 2014
192014
Spontaneous mutagenesis in human cells is controlled by REV1-Polymerase ζ and PRIMPOL
Z Gyüre, Á Póti, E Németh, B Szikriszt, R Lózsa, M Krawczyk, ...
Cell Reports 42 (8), 2023
182023
Design of a colicin E7 based chimeric zinc-finger nuclease
E Németh, GK Schilli, G Nagy, C Hasenhindl, B Gyurcsik, C Oostenbrink
Journal of Computer-Aided Molecular Design 28, 841-850, 2014
162014
Preorganization of the catalytic Zn2+-binding site in the HNH nuclease motif—A solution study
E Németh, M Kožíšek, GK Schilli, B Gyurcsik
Journal of Inorganic Biochemistry 151, 143-149, 2015
152015
A study on the secondary structure of the metalloregulatory protein CueR: effect of pH, metal ions and DNA
RK Balogh, E Németh, NC Jones, SV Hoffmann, A Jancsó, B Gyurcsik
European Biophysics Journal 50 (3), 491-500, 2021
102021
Substrate binding activates the designed triple mutant of the colicin E7 metallonuclease
E Németh, T Körtvélyesi, M Kožíšek, PW Thulstrup, HEM Christensen, ...
JBIC Journal of Biological Inorganic Chemistry 19, 1295-1303, 2014
102014
A new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational study
A Czene, E Tóth, E Németh, H Otten, JCN Poulsen, HEM Christensen, ...
Metallomics 6 (11), 2090-2099, 2014
102014
Intrinsic protein disorder could be overlooked in cocrystallization conditions: An SRCD case study
E Németh, RK Balogh, K Borsos, A Czene, PW Thulstrup, B Gyurcsik
Protein Science 25 (11), 1977-1988, 2016
92016
Chemical Approach to Biological Safety: Molecular‐Level Control of an Integrated Zinc Finger Nuclease
E Németh, MN Asaka, K Kato, Z Fábián, C Oostenbrink, HEM Christensen, ...
ChemBioChem 19 (1), 66-75, 2018
72018
The genomic imprint of cancer therapies helps timing the formation of metastases
E Németh, M Krzystanek, L Reiniger, D Ribli, O Pipek, Z Sztupinszki, ...
International journal of cancer 145 (3), 694-704, 2019
62019
DNA mismatch repair protects the genome from oxygen-induced replicative mutagenesis
R Lózsa, E Németh, JZ Gervai, BG Márkus, S Kollarics, Z Gyüre, J Tóth, ...
Nucleic Acids Research 51 (20), 11040-11055, 2023
52023
Recent results in the development of genebank technologies specialized for medicinal plants.
E Tóth, É Németh
41996
Cisplatin is more mutagenic than carboplatin or oxaliplatin at equitoxic concentrations
B Szikriszt, Á Póti, E Németh, N Kanu, C Swanton, D Szüts
bioRxiv, 2020.08. 11.245969, 2020
22020
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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