Obesity is associated with hypothalamic injury in rodents and humans JP Thaler, CX Yi, EA Schur, SJ Guyenet, BH Hwang, MO Dietrich, X Zhao, ... The Journal of clinical investigation 122 (1), 153-162, 2012 | 2004 | 2012 |
The relationship between high-fat dairy consumption and obesity, cardiovascular, and metabolic disease M Kratz, T Baars, S Guyenet European journal of nutrition 52 (1), 1-24, 2013 | 625 | 2013 |
Regulation of food intake, energy balance, and body fat mass: implications for the pathogenesis and treatment of obesity SJ Guyenet, MW Schwartz The Journal of Clinical Endocrinology & Metabolism 97 (3), 745-755, 2012 | 464 | 2012 |
A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia SJ Guyenet, SA Furrer, VM Damian, TD Baughan, AR La Spada, ... Journal of visualized experiments: JoVE, 1787, 2010 | 441 | 2010 |
Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport SK Custer, GA Garden, N Gill, U Rueb, RT Libby, C Schultz, SJ Guyenet, ... Nature neuroscience 9 (10), 1302-1311, 2006 | 275 | 2006 |
Hypothalamic inflammation: marker or mechanism of obesity pathogenesis? JP Thaler, SJ Guyenet, MD Dorfman, BE Wisse, MW Schwartz Diabetes 62 (8), 2629-2634, 2013 | 247 | 2013 |
Functional identification of a neurocircuit regulating blood glucose TH Meek, JT Nelson, ME Matsen, MD Dorfman, SJ Guyenet, V Damian, ... Proceedings of the National Academy of Sciences 113 (14), E2073-E2082, 2016 | 187 | 2016 |
A large‐scale mutagenesis screen to identify seizure‐resistant zebrafish SC Baraban, MT Dinday, PA Castro, S Chege, S Guyenet, MR Taylor Epilepsia 48 (6), 1151-1157, 2007 | 156 | 2007 |
Radiologic evidence that hypothalamic gliosis is associated with obesity and insulin resistance in humans EA Schur, SJ Melhorn, SK Oh, JM Lacy, KE Berkseth, SJ Guyenet, ... Obesity 23 (11), 2142-2148, 2015 | 137 | 2015 |
Hypothalamic gliosis associated with high-fat diet feeding is reversible in mice: a combined immunohistochemical and magnetic resonance imaging study KE Berkseth, SJ Guyenet, SJ Melhorn, D Lee, JP Thaler, EA Schur, ... Endocrinology 155 (8), 2858-2867, 2014 | 126 | 2014 |
BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production TH Meek, BE Wisse, JP Thaler, SJ Guyenet, ME Matsen, JD Fischer, ... Diabetes 62 (5), 1512-1518, 2013 | 106 | 2013 |
Increase in adipose tissue linoleic acid of US adults in the last half century SJ Guyenet, SE Carlson Advances in Nutrition 6 (6), 660-664, 2015 | 84 | 2015 |
The carbohydrate-insulin model of obesity is difficult to reconcile with current evidence KD Hall, SJ Guyenet, RL Leibel JAMA internal medicine 178 (8), 1103-1105, 2018 | 69 | 2018 |
The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction MA McCormick, AG Mason, SJ Guyenet, W Dang, RM Garza, MK Ting, ... Cell reports 8 (2), 477-486, 2014 | 69 | 2014 |
Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment S Mookerjee, T Papanikolaou, SJ Guyenet, V Sampath, A Lin, C Vitelli, ... Journal of Neuroscience 29 (48), 15134-15144, 2009 | 66 | 2009 |
Leptin action in the ventromedial hypothalamic nucleus is sufficient, but not necessary, to normalize diabetic hyperglycemia TH Meek, ME Matsen, MD Dorfman, SJ Guyenet, V Damian, HT Nguyen, ... Endocrinology 154 (9), 3067-3076, 2013 | 63 | 2013 |
High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes SJ Guyenet, HT Nguyen, BH Hwang, MW Schwartz, DG Baskin, JP Thaler Brain research 1512, 97-105, 2013 | 56 | 2013 |
Impact of whole, fresh fruit consumption on energy intake and adiposity: a systematic review SJ Guyenet Frontiers in nutrition 6, 443668, 2019 | 52 | 2019 |
The hungry brain: outsmarting the instincts that make us overeat SJ Guyenet Macmillan, 2017 | 47 | 2017 |
Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction SJ Guyenet, SS Mookerjee, A Lin, SK Custer, SF Chen, BL Sopher, ... Human molecular genetics 24 (14), 3908-3917, 2015 | 34 | 2015 |