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Kathleen B Yates
Kathleen B Yates
Broad Institute of MIT and Harvard
Email verificata su broadinstitute.org
Titolo
Citata da
Citata da
Anno
Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
BC Miller, DR Sen, R Al Abosy, K Bi, YV Virkud, MW LaFleur, KB Yates, ...
Nature immunology 20 (3), 326-336, 2019
17092019
In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
RT Manguso, HW Pope, MD Zimmer, FD Brown, KB Yates, BC Miller, ...
Nature 547 (7664), 413-418, 2017
11202017
The epigenetic landscape of T cell exhaustion
DR Sen, J Kaminski, RA Barnitz, M Kurachi, U Gerdemann, KB Yates, ...
Science 354 (6316), 1165-1169, 2016
9232016
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
6652018
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ...
Nature medicine 16 (10), 1147-1151, 2010
6202010
Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
JJ Ishizuka, RT Manguso, CK Cheruiyot, K Bi, A Panda, A Iracheta-Vellve, ...
Nature 565 (7737), 43-48, 2019
5852019
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
PK Gupta, J Godec, D Wolski, E Adland, K Yates, KE Pauken, C Cosgrove, ...
PLoS pathogens 11 (10), e1005177, 2015
4342015
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
M Kurachi, RA Barnitz, N Yosef, PM Odorizzi, MA DiIorio, ME Lemieux, ...
Nature immunology 15 (4), 373-383, 2014
3772014
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ...
Nature 595 (7866), 309-314, 2021
2672021
PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
MW LaFleur, TH Nguyen, MA Coxe, BC Miller, KB Yates, JE Gillis, ...
Nature immunology 20 (10), 1335-1347, 2019
1922019
Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans
KB Yates, P Tonnerre, GE Martin, U Gerdemann, R Al Abosy, ...
Nature immunology 22 (8), 1020-1029, 2021
1802021
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
J Dubrot, PP Du, SK Lane-Reticker, EA Kessler, AJ Muscato, A Mehta, ...
Nature Immunology 23 (10), 1495-1506, 2022
1232022
A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system
MW LaFleur, TH Nguyen, MA Coxe, KB Yates, JD Trombley, SA Weiss, ...
Nature Communications 10 (1), 1668, 2019
1152019
The PD-1 pathway regulates development and function of memory CD8+ T cells following respiratory viral infection
KE Pauken, J Godec, PM Odorizzi, KE Brown, KB Yates, SF Ngiow, ...
Cell reports 31 (13), 2020
1062020
Targeting TBK1 to overcome resistance to cancer immunotherapy
Y Sun, O Revach, S Anderson, EA Kessler, CH Wolfe, A Jenney, CE Mills, ...
Nature 615 (7950), 158-167, 2023
872023
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection
P Penaloza-MacMaster, DL Barber, EJ Wherry, NM Provine, JE Teigler, ...
Science 347 (6219), 278-282, 2015
862015
Targeted reconstruction of T cell receptor sequence from single cell RNA-seq links CDR3 length to T cell differentiation state
S Afik, KB Yates, K Bi, S Darko, J Godec, U Gerdemann, L Swadling, ...
Nucleic acids research 45 (16), e148-e148, 2017
802017
TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response
Z Zeng, CJ Wong, L Yang, N Ouardaoui, D Li, W Zhang, S Gu, Y Zhang, ...
Nucleic acids research 50 (D1), D1391-D1397, 2022
792022
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation. Cancer Discov. 2018; 8: 216–233. doi: 10.1158/2159-8290
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
CD-17-0915.[Europe PMC free article][Abstract][CrossRef][Academic Search], 0
79
The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity
CK Baumgartner, H Ebrahimi-Nik, A Iracheta-Vellve, KM Hamel, ...
Nature 622 (7984), 850-862, 2023
762023
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