First toxicity report of tetrodotoxin and 5, 6, 11-trideoxyTTX in the trumpet shell Charonia lampas lampas in Europe P Rodriguez, A Alfonso, C Vale, C Alfonso, P Vale, A Tellez, LM Botana Analytical chemistry 80 (14), 5622-5629, 2008 | 200 | 2008 |
The effect of bilateral deafness on excitatory and inhibitory synaptic strength in the inferior colliculus C Vale, DH Sanes European Journal of Neuroscience 16 (12), 2394-2404, 2002 | 183 | 2002 |
First toxin profile of ciguateric fish in Madeira Arquipelago (Europe) P Otero, S Perez, A Alfonso, C Vale, P Rodríguez, NN Gouveia, ... Analytical chemistry 82 (14), 6032-6039, 2010 | 173 | 2010 |
Allosteric positive interaction of thymol with the GABAA receptor in primary cultures of mouse cortical neurons DA García, J Bujons, C Vale, C Suñol Neuropharmacology 50 (1), 25-35, 2006 | 159 | 2006 |
The organochlorine pesticides γ-hexachlorocyclohexane (lindane), α-endosulfan and dieldrin differentially interact with GABAA and glycine-gated chloride channels in primary … C Vale, E Fonfra, J Bujons, A Messeguer, E Rodrguez-Farr, C Suol Neuroscience 117 (2), 397-403, 2003 | 116 | 2003 |
Afferent regulation of inhibitory synaptic transmission in the developing auditory midbrain C Vale, DH Sanes Journal of Neuroscience 20 (5), 1912-1921, 2000 | 112 | 2000 |
Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins C Vale, LM Botana The FEBS journal 275 (24), 6060-6066, 2008 | 102 | 2008 |
In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction C Vale, A Alfonso, MR Vieytes, XM Romarís, F Arevalo, AM Botana, ... Analytical Chemistry 80 (5), 1770-1776, 2008 | 91 | 2008 |
Deafness disrupts chloride transporter function and inhibitory synaptic transmission C Vale, J Schoorlemmer, DH Sanes Journal of Neuroscience 23 (20), 7516-7524, 2003 | 90 | 2003 |
Effects of Azaspiracid-1, A Potent Cytotoxic Agent, on Primary Neuronal Cultures. A Structure− Activity Relationship Study C Vale, KC Nicolaou, MO Frederick, B Gómez-Limia, A Alfonso, ... Journal of medicinal chemistry 50 (2), 356-363, 2007 | 85 | 2007 |
13-Desmethyl spirolide-C is neuroprotective and reduces intracellular Aβ and hyperphosphorylated tau in vitro E Alonso, C Vale, MR Vieytes, FM Laferla, L Giménez-Llort, LM Botana Neurochemistry international 59 (7), 1056-1065, 2011 | 83 | 2011 |
Design and synthesis of skeletal analogues of gambierol: Attenuation of amyloid-β and tau pathology with voltage-gated potassium channel and N-methyl-D-aspartate receptor … E Alonso, H Fuwa, C Vale, Y Suga, T Goto, Y Konno, M Sasaki, ... Journal of the American Chemical Society 134 (17), 7467-7479, 2012 | 80 | 2012 |
Unilateral cochlear ablation produces greater loss of inhibition in the contralateral inferior colliculus C Vale, JM Juíz, DR Moore, DH Sanes European Journal of Neuroscience 20 (8), 2133-2140, 2004 | 75 | 2004 |
Additional bioactive guanidine alkaloids from the Mediterranean sponge Crambe crambe S Bondu, G Genta-Jouve, M Leirόs, C Vale, JM Guigonis, LM Botana, ... Rsc Advances 2 (7), 2828-2835, 2012 | 72 | 2012 |
Functional assays for marine toxins as an alternative, high-throughput-screening solution to animal tests LM Botana, A Alfonso, A Botana, MR Vieytes, C Vale, N Vilariño, ... TrAC Trends in Analytical Chemistry 28 (5), 603-611, 2009 | 69 | 2009 |
Benefit of 13-desmethyl spirolide C treatment in triple transgenic mouse model of Alzheimer disease: beta-amyloid and neuronal markers improvement E Alonso, P Otero, C Vale, A Alfonso, A Antelo, L Giménez-Llort, ... Current Alzheimer Research 10 (3), 279-289, 2013 | 63 | 2013 |
The problem of toxicity equivalent factors in developing alternative methods to animal bioassays for marine-toxin detection LM Botana, N Vilarino, A Alfonso, C Vale, C Louzao, CT Elliott, ... TrAC Trends in Analytical Chemistry 29 (11), 1316-1325, 2010 | 63 | 2010 |
The Cholinergic Antagonist Gymnodimine Improves Aβ and Tau Neuropathology in an in Vitro Model of Alzheimer Disease E Alonso, C Vale, MR Vieytes, FM Laferla, L Giménez-Llort, LM Botana Cellular Physiology and Biochemistry 27 (6), 783-794, 2011 | 57 | 2011 |
Profile for amyloid-β and tau expression in primary cortical cultures from 3xTg-AD mice C Vale, E Alonso, JA Rubiolo, MR Vieytes, FM LaFerla, L Giménez-Llort, ... Cellular and molecular neurobiology 30, 577-590, 2010 | 56 | 2010 |
Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from Gambierdiscus belizeanus A Boente-Juncal, M Álvarez, Á Antelo, I Rodríguez, K Calabro, C Vale, ... Toxins 11 (2), 79, 2019 | 54 | 2019 |