Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity MD Larsen, EL de Graaf, ME Sonneveld, HR Plomp, J Nouta, W Hoepel, ... Science 371 (6532), eabc8378, 2021 | 367 | 2021 |
Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes SW De Taeye, G Ozorowski, AT de la Peña, M Guttman, JP Julien, ... Cell 163 (7), 1702-1715, 2015 | 364 | 2015 |
Elicitation of robust tier 2 neutralizing antibody responses in nonhuman primates by HIV envelope trimer immunization using optimized approaches M Pauthner, C Havenar-Daughton, D Sok, JP Nkolola, R Bastidas, ... Immunity 46 (6), 1073-1088. e6, 2017 | 319 | 2017 |
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021 | 207 | 2021 |
Murine antibody responses to cleaved soluble HIV-1 envelope trimers are highly restricted in specificity JK Hu, JC Crampton, A Cupo, T Ketas, MJ van Gils, K Sliepen, ... Journal of virology 89 (20), 10383-10398, 2015 | 181 | 2015 |
FcγR binding and ADCC activity of human IgG allotypes SW De Taeye, AEH Bentlage, MM Mebius, JI Meesters, ... Frontiers in immunology 11, 740, 2020 | 178 | 2020 |
The ligands for human IgG and their effector functions SW de Taeye, T Rispens, G Vidarsson Antibodies 8 (2), 30, 2019 | 177 | 2019 |
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo M Medina-Ramírez, F Garces, A Escolano, P Skog, SW de Taeye, ... Journal of Experimental Medicine 214 (9), 2573-2590, 2017 | 173 | 2017 |
Direct probing of germinal center responses reveals immunological features and bottlenecks for neutralizing antibody responses to HIV Env trimer C Havenar-Daughton, DG Carnathan, AT de la Peña, M Pauthner, ... Cell reports 17 (9), 2195-2209, 2016 | 173 | 2016 |
Improving the immunogenicity of native-like HIV-1 envelope trimers by hyperstabilization AT de la Pena, JP Julien, SW de Taeye, F Garces, M Guttman, ... Cell reports 20 (8), 1805-1817, 2017 | 162 | 2017 |
An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability MJ Van Gils, TLGM Van Den Kerkhof, G Ozorowski, CA Cottrell, D Sok, ... Nature microbiology 2 (2), 1-10, 2016 | 155 | 2016 |
Design and structure of two HIV-1 clade C SOSIP. 664 trimers that increase the arsenal of native-like Env immunogens JP Julien, JH Lee, G Ozorowski, Y Hua, A Torrents de la Peña, ... Proceedings of the National Academy of Sciences 112 (38), 11947-11952, 2015 | 129 | 2015 |
Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferons V Cobos Jiménez, T Booiman, SW de Taeye, KA van Dort, MAN Rits, ... Scientific reports 2 (1), 763, 2012 | 127 | 2012 |
HIV-1 envelope trimer design and immunization strategies to induce broadly neutralizing antibodies SW de Taeye, JP Moore, RW Sanders Trends in immunology 37 (3), 221-232, 2016 | 122 | 2016 |
Comprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer R Derking, G Ozorowski, K Sliepen, A Yasmeen, A Cupo, JL Torres, ... PLoS pathogens 11 (3), e1004767, 2015 | 119 | 2015 |
Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike JH Lee, DP Leaman, AS Kim, A Torrents de La Peña, K Sliepen, ... Nature communications 6 (1), 8167, 2015 | 104 | 2015 |
Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets AP Bye, W Hoepel, JL Mitchell, S Jégouic, S Loureiro, T Sage, ... Blood, The Journal of the American Society of Hematology 138 (16), 1481-1489, 2021 | 93 | 2021 |
Torrents de la Pena A, Guttman M, Julien JP, van den Kerkhof TL, et al. Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes SW De Taeye, G Ozorowski Cell 163 (7), 1702-15, 2015 | 87 | 2015 |
Immunogenicity in rabbits of HIV-1 SOSIP trimers from clades A, B, and C, given individually, sequentially, or in combination A Torrents de la Peña, SW de Taeye, K Sliepen, CC LaBranche, ... Journal of virology 92 (8), 10.1128/jvi. 01957-17, 2018 | 84 | 2018 |
Functional attributes of antibodies, effector cells, and target cells affecting NK cell–mediated antibody-dependent cellular cytotoxicity AR Temming, SW de Taeye, EL de Graaf, LA de Neef, G Dekkers, ... The Journal of Immunology 203 (12), 3126-3135, 2019 | 83 | 2019 |