| A new era for understanding amyloid structures and disease MG Iadanza, MP Jackson, EW Hewitt, NA Ranson, SE Radford Nature reviews Molecular cell biology 19 (12), 755-773, 2018 | 981 | 2018 |
| The MHC class I antigen presentation pathway: strategies for viral immune evasion EW Hewitt Immunology 110 (2), 163-169, 2003 | 681 | 2003 |
| An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation B Manoury, EW Hewitt, N Morrice, PM Dando, AJ Barrett, C Watts Nature 396 (6712), 695-699, 1998 | 484 | 1998 |
| Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase JM Chen, PM Dando, ND Rawlings, MA Brown, NE Young, RA Stevens, ... Journal of Biological Chemistry 272 (12), 8090-8098, 1997 | 483 | 1997 |
| Fibril Fragmentation Enhances Amyloid Cytotoxicity*♦ WF Xue, AL Hellewell, WS Gosal, SW Homans, EW Hewitt, SE Radford Journal of Biological Chemistry 284 (49), 34272-34282, 2009 | 446 | 2009 |
| Natural killer cell cytotoxicity: how do they pull the trigger? NJ Topham, EW Hewitt Immunology 128 (1), 7-15, 2009 | 429 | 2009 |
| Competing pathways determine fibril morphology in the self-assembly of β2-microglobulin into amyloid WS Gosal, IJ Morten, EW Hewitt, DA Smith, NH Thomson, SE Radford Journal of molecular biology 351 (4), 850-864, 2005 | 424 | 2005 |
| The human cytomegalovirus gene product US6 inhibits ATP binding by TAP EW Hewitt, SS Gupta, PJ Lehner The EMBO journal, 2001 | 260 | 2001 |
| Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101‐dependent degradation EW Hewitt, L Duncan, D Mufti, J Baker, PG Stevenson, PJ Lehner The EMBO journal, 2002 | 231 | 2002 |
| Direct three-dimensional visualization of membrane disruption by amyloid fibrils L Milanesi, T Sheynis, WF Xue, EV Orlova, AL Hellewell, R Jelinek, ... Proceedings of the National Academy of Sciences 109 (50), 20455-20460, 2012 | 214 | 2012 |
| Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells A Cherukuri, DM Rothstein, B Clark, CR Carter, A Davison, ... Journal of the American Society of Nephrology 25 (7), 1575-1585, 2014 | 182 | 2014 |
| Cellular proteostasis: degradation of misfolded proteins by lysosomes MP Jackson, EW Hewitt Essays in biochemistry 60 (2), 173-180, 2016 | 180 | 2016 |
| The structures of the HC fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding P Emsley, C Fotinou, I Black, NF Fairweather, IG Charles, C Watts, ... Journal of Biological Chemistry 275 (12), 8889-8894, 2000 | 180 | 2000 |
| A Systematic Study of the Effect of Physiological Factors on β2-Microglobulin Amyloid Formation at Neutral pH SL Myers, S Jones, TR Jahn, IJ Morten, GA Tennent, EW Hewitt, ... Biochemistry 45 (7), 2311-2321, 2006 | 158 | 2006 |
| Fibril fragmentation in amyloid assembly and cytotoxicity: when size matters WF Xue, AL Hellewell, EW Hewitt, SE Radford Prion 4 (1), 20-25, 2010 | 140 | 2010 |
| The S. cerevisiae SEC65 gene encodes a component of yeast signal recognition particle with homology to human SRP19 CJ Stirling, EW Hewitt Nature 356 (6369), 534-537, 1992 | 139 | 1992 |
| pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers KW Tipping, TK Karamanos, T Jakhria, MG Iadanza, SC Goodchild, ... Proceedings of the National Academy of Sciences 112 (18), 5691-5696, 2015 | 132 | 2015 |
| Amyloid fibres: inert end-stage aggregates or key players in disease? KW Tipping, P van Oosten-Hawle, EW Hewitt, SE Radford Trends in biochemical sciences 40 (12), 719-727, 2015 | 126 | 2015 |
| Ligand binding to distinct states diverts aggregation of an amyloid-forming protein LA Woods, GW Platt, AL Hellewell, EW Hewitt, SW Homans, AE Ashcroft, ... Nature chemical biology 7 (10), 730-739, 2011 | 124 | 2011 |
| Why are functional amyloids non-toxic in humans? MP Jackson, EW Hewitt Biomolecules 7 (4), 71, 2017 | 121 | 2017 |
