| The influence of placental metabolism on fatty acid transfer to the fetus S Perazzolo, B Hirschmugl, C Wadsack, G Desoye, RM Lewis, ... Journal of lipid research 58 (2), 443-454, 2017 | 120 | 2017 |
| Three HIV drugs, atazanavir, ritonavir, and tenofovir, coformulated in drug-combination nanoparticles exhibit long-acting and lymphocyte-targeting properties in nonhuman primates S Perazzolo, LM Shireman, J Koehn, LA McConnachie, JC Kraft, ... Journal of pharmaceutical sciences 107 (12), 3153-3162, 2018 | 46 | 2018 |
| Modelling the effect of intervillous flow on solute transfer based on 3D imaging of the human placental microstructure S Perazzolo, RM Lewis, BG Sengers Placenta 60, 21-27, 2017 | 31 | 2017 |
| Phenylalanine transfer across the isolated perfused human placenta: an experimental and modeling investigation EM Lofthouse, S Perazzolo, S Brooks, IP Crocker, JD Glazier, ... AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE …, 2016 | 25 | 2016 |
| Integration of computational and experimental approaches to elucidate mechanisms of first-pass lymphatic drug sequestration and long-acting pharmacokinetics of the injectable … S Perazzolo, LM Shireman, LA McConnachie, J Koehn, L Kinman, W Lee, ... Journal of pharmaceutical sciences 109 (5), 1789-1801, 2020 | 21 | 2020 |
| In vivo kinetic study of materno‐fetal fatty acid transfer in obese and normal weight pregnant women A Gázquez, MT Prieto‐Sánchez, JE Blanco‐Carnero, D van Harskamp, ... The Journal of physiology 597 (19), 4959-4973, 2019 | 21 | 2019 |
| Systems and clinical pharmacology of COVID-19 therapeutic candidates: a clinical and translational medicine perspective S Perazzolo, L Zhu, W Lin, A Nguyen, RJY Ho Journal of Pharmaceutical Sciences 110 (3), 1002-1017, 2021 | 20 | 2021 |
| Placental mobilization of free fatty acids contributes to altered materno-fetal transfer in obesity B Hirschmugl, S Perazzolo, BG Sengers, RM Lewis, M Gruber, G Desoye, ... International Journal of Obesity 45 (5), 1114-1123, 2021 | 15 | 2021 |
| Physiologically based pharmacokinetic modeling of 3 HIV drugs in combination and the role of lymphatic system after subcutaneous dosing. Part 2: model for the drug-combination … S Perazzolo, DD Shen, RJY Ho Journal of pharmaceutical sciences 111 (3), 825-837, 2022 | 13 | 2022 |
| Computational modelling of fatty acid transport in the human placenta S Perazzolo, B Hirschmugl, C Wadsack, G Desoye, RM Lewis, ... IEEE Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual …, 2015 | 12 | 2015 |
| Novel long-acting drug combination nanoparticles composed of gemcitabine and paclitaxel enhance localization of both drugs in metastatic breast cancer nodules J Yu, Q Mu, S Perazzolo, JI Griffin, L Zhu, LA McConnachie, DD Shen, ... Pharmaceutical research 37, 1-18, 2020 | 11 | 2020 |
| Physiologically based pharmacokinetic modeling of 3 HIV drugs in combination and the role of lymphatic system after subcutaneous dosing. Part 1: model for the free-drug mixture S Perazzolo, LM Shireman, DD Shen, RJY Ho Journal of pharmaceutical sciences 111 (2), 529-541, 2022 | 9 | 2022 |
| A novel formulation enabled transformation of 3-HIV drugs tenofovir–lamivudine–dolutegravir from short-acting to long-acting all-in-one injectable S Perazzolo, ZR Stephen, M Eguchi, X Xu, R Delle Fratte, AC Collier, ... AIDS 37 (14), 2131-2136, 2023 | 8 | 2023 |
| Bictegravir plus tenofovir alafenamide nanoformulation as a long-acting pre-exposure prophylaxis regimen: application of modeling to design non-human primate pharmacokinetic … S Perazzolo, S Mandal, PK Prathipati, CJ Destache Frontiers in Pharmacology 11, 603242, 2020 | 7 | 2020 |
| Physiologically based pharmacokinetic model validated to enable predictions of multiple drugs in a long-acting drug-combination nano-particles (DCNP): confirmation with 3 HIV … S Perazzolo, DD Shen, AM Scott, RJY Ho Journal of Pharmaceutical Sciences 113 (6), 1653-1663, 2024 | 5 | 2024 |
| Modelling nutrient transfer based on 3D imaging of the human placental microstructure S Perazzolo, RM Lewis, BG Sengers IEEE Engineering in Medicine and Biology Society (EMBC), 2016 38th Annual …, 2016 | 3 | 2016 |
| Using disposition index to detect early impairment of beta cell function. 19th IDS Congress M Martino, A Carr, S Perazzolo, A Galderisi, L Marcovecchio, C Dayan Immunology of Diabetes Society (IDS), Paris, 23–26 May [Poster presentation], 2023 | 2* | 2023 |
| Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques S Srinivasula, P Degrange, S Perazzolo, A Bonvillain, A Tobery, J Kaplan, ... Frontiers in Immunology 14, 1213455, 2023 | 1 | 2023 |
| Modelling nutrient transfer across the placenta S Perazzolo University of Southampton, 2017 | 1 | 2017 |
| SAAM II: A general mathematical modeling rapid prototyping environment S Perazzolo CPT: Pharmacometrics & Systems Pharmacology, 2024 | | 2024 |
Rohan LewisProfessor of Placental and Integrative Physiology, Faculty of Medicine, University of SouthamptonEmail verificata su soton.ac.uk