| Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ... Nature 579 (7800), 586-591, 2020 | 442 | 2020 |
| Global phosphoproteomic analysis of human skeletal muscle reveals a network of exercise-regulated kinases and AMPK substrates NJ Hoffman, BL Parker, R Chaudhuri, KH Fisher-Wellman, M Kleinert, ... Cell metabolism 22 (5), 922-935, 2015 | 435 | 2015 |
| ATP-citrate lyase controls a glucose-to-acetate metabolic switch S Zhao, AM Torres, RA Henry, S Trefely, M Wallace, JV Lee, A Carrer, ... Cell reports 17 (4), 1037-1052, 2016 | 397 | 2016 |
| Acetyl-CoA metabolism supports multistep pancreatic tumorigenesis A Carrer, S Trefely, S Zhao, SL Campbell, RJ Norgard, KC Schultz, ... Cancer discovery 9 (3), 416-435, 2019 | 279 | 2019 |
| Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47− mediated ‘don’t-eat-me’signal M Liu, RS O’Connor, S Trefely, K Graham, NW Snyder, GL Beatty Nature immunology 20 (3), 265-275, 2019 | 253 | 2019 |
| Compartmentalised acyl-CoA metabolism and roles in chromatin regulation S Trefely, CD Lovell, NW Snyder, KE Wellen Molecular metabolism 38, 100941, 2020 | 196 | 2020 |
| A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate W Wang, J Ishibashi, S Trefely, M Shao, AJ Cowan, A Sakers, HW Lim, ... Cell metabolism 30 (1), 174-189. e5, 2019 | 195 | 2019 |
| Impact of a high-fat diet on tissue Acyl-CoA and histone acetylation levels A Carrer, JLD Parris, S Trefely, RA Henry, DC Montgomery, AM Torres, ... Journal of Biological Chemistry 292 (8), 3312-3322, 2017 | 180 | 2017 |
| The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations RS O’Connor, L Guo, S Ghassemi, NW Snyder, AJ Worth, L Weng, Y Kam, ... Scientific reports 8 (1), 6289, 2018 | 177 | 2018 |
| Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy PK Kopinski, KA Janssen, PM Schaefer, S Trefely, CE Perry, P Potluri, ... Proceedings of the National Academy of Sciences 116 (32), 16028-16035, 2019 | 147 | 2019 |
| mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis CM Calejman, S Trefely, SW Entwisle, A Luciano, SM Jung, W Hsiao, ... Nature Communications 11 (1), 1-16, 2020 | 140 | 2020 |
| Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+–NFAT signaling JV Lee, CT Berry, K Kim, P Sen, T Kim, A Carrer, S Trefely, S Zhao, ... Genes & development 32 (7-8), 497-511, 2018 | 126 | 2018 |
| FluxFix: automatic isotopologue normalization for metabolic tracer analysis S Trefely, P Ashwell, NW Snyder BMC bioinformatics 17 (1), 485, 2016 | 104 | 2016 |
| LC-quadrupole/Orbitrap high-resolution mass spectrometry enables stable isotope-resolved simultaneous quantification and 13C-isotopic labeling of acyl … AJ Frey, DR Feldman, S Trefely, AJ Worth, SS Basu, NW Snyder Analytical and bioanalytical chemistry 408, 3651-3658, 2016 | 95 | 2016 |
| Adipocyte ACLY facilitates dietary carbohydrate handling to maintain metabolic homeostasis in females S Fernandez, JM Viola, AM Torres, M Wallace, S Trefely, S Zhao, ... Cell reports 27 (9), 2772-2784. e6, 2019 | 83 | 2019 |
| Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism S Shah, WJ Carriveau, J Li, SL Campbell, PK Kopinski, HW Lim, N Daurio, ... Oncotarget 7 (28), 43713, 2016 | 79 | 2016 |
| Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues EL Varner, S Trefely, D Bartee, E von Krusenstiern, L Izzo, C Bekeova, ... Open Biology 10 (9), 200187, 2020 | 74 | 2020 |
| Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation S Trefely, K Huber, J Liu, M Noji, S Stransky, J Singh, MT Doan, CD Lovell, ... Molecular cell 82 (2), 447-462. e6, 2022 | 73 | 2022 |
| Kinome screen identifies PFKFB3 and glucose metabolism as important regulators of the insulin/insulin-like growth factor (IGF)-1 signaling pathway S Trefely, PS Khoo, JR Krycer, R Chaudhuri, DJ Fazakerley, BL Parker, ... Journal of Biological Chemistry 290 (43), 25834-25846, 2015 | 67 | 2015 |
| Structural basis for phosphorylation and lysine acetylation cross-talk in a kinase motif associated with myocardial ischemia and cardioprotection BL Parker, NE Shepherd, S Trefely, NJ Hoffman, MY White, ... Journal of Biological Chemistry 289 (37), 25890-25906, 2014 | 53 | 2014 |