John E Burke

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i10-index	96	93

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12 articoli

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Roger L WilliamsGroup leader, Medical Research Council, Laboratory of Molecular BiologyEmail verificata su mrc-lmb.cam.ac.uk
Meredith L JenkinsLab Manager, University of VictoriaEmail verificata su uvic.ca
Glenn R. MassonUniversity of Dundee, School of MedicineEmail verificata su dundee.ac.uk
Oscar VadasPostdoc at the Medical Research Council - Laboratory of Molecular Biology, Cambridge, UKEmail verificata su unige.ch
Jacob A McPhailPhD, Professional Researcher (Full) at UCSFEmail verificata su ucsf.edu
Manoj RathinaswamyCalico Life SciencesEmail verificata su calicolabs.com
Calvin YipProfessor of Biochemistry and Molecular Biology, the University of British ColumbiaEmail verificata su ubc.ca
jan steyaertVIB-VUB center for Structural Biology, BrusselsEmail verificata su vub.be
Els Pardonvrije universiteit brusselEmail verificata su vub.ac.be
Braden D. SiempelkampUniversity of VictoriaEmail verificata su uvic.ca
Martin J BoulangerUniversity of VictoriaEmail verificata su uvic.ca
Yuan-Hao Hsu (許員豪)Department of Chemistry, Tunghai University/東海大學化學系Email verificata su thu.edu.tw
Yohei OhashiLaboratory of Molecular Biology, Medical Research CouncilEmail verificata su mrc-lmb.cam.ac.uk
Hashem DboukEmail verificata su phd.einstein.yu.edu
Alex BerndtResearch Scientist MRC-LMBEmail verificata su mrc-lmb.cam.ac.uk
Alan SmrckaProfessor of Pharmacology, University of MichiganEmail verificata su umich.edu
Peter R ShepherdEmail verificata su auckland.ac.nz
Alisdair BorastonProfessor of Biochemistry and Microbiology, University of VictoriaEmail verificata su uvic.ca
George KokotosProfessor of Organic Chemistry, National and Kapodistrian University of AthensEmail verificata su chem.uoa.gr
Joseph J. FalkeDirector of Molecular Biophysics, Prof. of Chemistry & Biochemistry, CU BoulderEmail verificata su colorado.edu

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John E Burke

Professor of Biochemistry and Microbiology, University of Victoria

Email verificata su uvic.ca - Home page

X-ray crystallography HDX-MS hydrogen exchange PI3K phosphoinositides


Titolo Ordina per citazioni Ordina per anno Ordina per titolo	Citata da Citata da	Anno
Accurate prediction of protein structures and interactions using a three-track neural network M Baek, F DiMaio, I Anishchenko, J Dauparas, S Ovchinnikov, GR Lee, ... Science 373 (6557), 871-876, 2021	4457	2021
Phospholipase A2 structure/function, mechanism, and signaling1 JE Burke, EA Dennis Journal of lipid research 50, S237-S242, 2009	1129	2009
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019	640	2019
Phospholipase A₂ Biochemistry JE Burke, EA Dennis Cardiovascular drugs and therapy 23, 49-59, 2009	568	2009
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases O Vadas, JE Burke, X Zhang, A Berndt, RL Williams Science signaling 4 (195), re2-re2, 2011	327	2011
Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) JE Burke, O Perisic, GR Masson, O Vadas, RL Williams Proceedings of the National Academy of Sciences, 2012	312	2012
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes K Rostislavleva, N Soler, Y Ohashi, L Zhang, E Pardon, JE Burke, ... Science 350 (6257), aac7365, 2015	272	2015
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors N Kato, E Comer, T Sakata-Kato, A Sharma, M Sharma, M Maetani, ... Nature 538 (7625), 344-349, 2016	267	2016
Structural basis for regulation of phosphoinositide kinases and their involvement in human disease JE Burke Molecular cell 71 (5), 653-673, 2018	243	2018
Synergy in activating class I PI3Ks JE Burke, RL Williams Trends in biochemical sciences 40 (2), 88-100, 2015	212	2015
G protein–coupled receptor–mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness HA Dbouk, O Vadas, A Shymanets, JE Burke, RS Salamon, BD Khalil, ... Science signaling 5 (253), ra89-ra89, 2012	176	2012
An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery GR Masson, ML Jenkins, JE Burke Expert opinion on drug discovery 12 (10), 981-994, 2017	175	2017
Novel roles of phosphoinositides in signaling, lipid transport, and disease GRV Hammond, JE Burke Current Opinion in Cell Biology 63, 57-67, 2020	174	2020
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi G D’Angelo, T Uemura, CC Chuang, E Polishchuk, M Santoro, ... Nature 501 (7465), 116-120, 2013	170	2013
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne TET Mevissen, Y Kulathu, MPC Mulder, PP Geurink, SL Maslen, M Gersch, ... Nature 538 (7625), 402-405, 2016	163	2016
Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs) O Vadas, HA Dbouk, A Shymanets, O Perisic, JE Burke, WF Abi Saab, ... Proceedings of the National Academy of Sciences 110 (47), 18862-18867, 2013	160	2013
Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors JE Burke, AJ Inglis, O Perisic, GR Masson, SH McLaughlin, F Rutaganira, ... Science 344 (6187), 1035-1038, 2014	152	2014
Dynamics of the Phosphoinositide 3-Kinase p110 [delta] Interaction with p85 [alpha] and Membranes Reveals Aspects of Regulation Distinct from p110 [alpha] JE Burke, O Vadas, A Berndt, T Finegan, O Perisic, RL Williams Structure 19 (8), 1127-1137, 2011	122	2011
Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1 GL Dornan, BD Siempelkamp, ML Jenkins, O Vadas, CL Lucas, JE Burke Proceedings of the National Academy of Sciences 114 (8), 1982-1987, 2017	115	2017
Ras binder induces a modified switch-II pocket in GTP and GDP states DR Gentile, MK Rathinaswamy, ML Jenkins, SM Moss, BD Siempelkamp, ... Cell chemical biology 24 (12), 1455-1466. e14, 2017	113	2017

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