Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion CM Sousa, DE Biancur, X Wang, CJ Halbrook, MH Sherman, LI Zhang, ... Nature 536 (7617), 479-483, 2016 | 1077 | 2016 |
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I K Yamamoto, A Venida, J Yano, DE Biancur, M Kakiuchi, S Gupta, ... Nature 581 (7806), 100-105, 2020 | 935 | 2020 |
Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis JD Mancias, L Pontano Vaites, S Nissim, DE Biancur, AJ Kim, X Wang, ... elife 4, e10308, 2015 | 445 | 2015 |
Autophagy sustains pancreatic cancer growth through both cell-autonomous and nonautonomous mechanisms A Yang, G Herter-Sprie, H Zhang, EY Lin, D Biancur, X Wang, J Deng, ... Cancer discovery 8 (3), 276-287, 2018 | 306 | 2018 |
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism DE Biancur, JA Paulo, B Małachowska, M Quiles Del Rey, CM Sousa, ... Nature communications 8 (1), 15965, 2017 | 292 | 2017 |
Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer VI Sayin, SE LeBoeuf, SX Singh, SM Davidson, D Biancur, BS Guzelhan, ... Elife 6, e28083, 2017 | 217 | 2017 |
Neurons release serine to support mRNA translation in pancreatic cancer RS Banh, DE Biancur, K Yamamoto, ASW Sohn, B Walters, M Kuljanin, ... Cell 183 (5), 1202-1218. e25, 2020 | 205 | 2020 |
Nanoparticle mediated tumor vascular disruption: a novel strategy in radiation therapy S Kunjachan, A Detappe, R Kumar, T Ireland, L Cameron, DE Biancur, ... Nano letters 15 (11), 7488-7496, 2015 | 164 | 2015 |
Selective alanine transporter utilization creates a targetable metabolic niche in pancreatic cancer SJ Parker, CR Amendola, KER Hollinshead, Q Yu, K Yamamoto, ... Cancer discovery 10 (7), 1018-1037, 2020 | 137 | 2020 |
The plasticity of pancreatic cancer metabolism in tumor progression and therapeutic resistance DE Biancur, AC Kimmelman Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1870 (1), 67-75, 2018 | 136 | 2018 |
Interleukin-17 governs hypoxic adaptation of injured epithelium P Konieczny, Y Xing, I Sidhu, I Subudhi, KP Mansfield, B Hsieh, ... Science 377 (6602), eabg9302, 2022 | 127 | 2022 |
Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy A Detappe, S Kunjachan, L Sancey, V Motto-Ros, D Biancur, P Drane, ... Journal of Controlled Release 238, 103-113, 2016 | 109 | 2016 |
NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron–sulfur cluster proteins N Santana-Codina, MQ Del Rey, KS Kapner, H Zhang, A Gikandi, ... Cancer discovery 12 (9), 2180-2197, 2022 | 90 | 2022 |
Functional genomics identifies metabolic vulnerabilities in pancreatic cancer DE Biancur, KS Kapner, K Yamamoto, RS Banh, JE Neggers, ASW Sohn, ... Cell metabolism 33 (1), 199-210. e8, 2021 | 81 | 2021 |
Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11 S Mukhopadhyay, DE Biancur, SJ Parker, K Yamamoto, RS Banh, ... Proceedings of the National Academy of Sciences 118 (6), e2021475118, 2021 | 74 | 2021 |
NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms N Santana-Codina, S Gableske, MQ del Rey, B Małachowska, ... Haematologica 104 (7), 1342, 2019 | 60 | 2019 |
Key clinical beam parameters for nanoparticle-mediated radiation dose amplification A Detappe, S Kunjachan, P Drané, S Kotb, M Myronakis, DE Biancur, ... Scientific reports 6 (1), 34040, 2016 | 43 | 2016 |
The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway RS Banh, ES Kim, Q Spillier, DE Biancur, K Yamamoto, ASW Sohn, G Shi, ... Nature 597 (7876), 420-425, 2021 | 41 | 2021 |
Targeting pancreatic cancer metabolic dependencies through glutamine antagonism J Encarnación-Rosado, ASW Sohn, DE Biancur, EY Lin, ... Nature cancer 5 (1), 85-99, 2024 | 40 | 2024 |
Noninvasive imaging of tumor hypoxia after nanoparticle-mediated tumor vascular disruption NA Virani, OJ Kelada, S Kunjachan, A Detappe, J Kwon, J Hayashi, ... Plos one 15 (7), e0236245, 2020 | 4 | 2020 |