| Enhanced protein and biochemical production using CRISPRi-based growth switches S Li, CB Jendresen, A Grünberger, C Ronda, SI Jensen, S Noack, ... Metabolic engineering 38, 274-284, 2016 | 100 | 2016 |
| BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B MA Coelho, S Li, LS Pane, M Firth, G Ciotta, JD Wrigley, ME Cuomo, ... BMC biology 16, 1-11, 2018 | 61 | 2018 |
| Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing S Wimberger, N Akrap, M Firth, J Brengdahl, S Engberg, MK Schwinn, ... Nature communications 14 (1), 4761, 2023 | 50 | 2023 |
| Awakening dormant glycosyltransferases in CHO cells with CRISPRa KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ... Biotechnology and bioengineering 117 (2), 593-598, 2020 | 43 | 2020 |
| Genome-wide CRISPRi-based identification of targets for decoupling growth from production S Li, CB Jendresen, J Landberg, LE Pedersen, N Sonnenschein, ... ACS Synthetic Biology 9 (5), 1030-1040, 2020 | 42 | 2020 |
| Universal toxin-based selection for precise genome engineering in human cells S Li, N Akrap, S Cerboni, MJ Porritt, S Wimberger, A Lundin, C Möller, ... Nature communications 12 (1), 497, 2021 | 37 | 2021 |
| Harnessing DSB repair to promote efficient homology-dependent and-independent prime editing M Peterka, N Akrap, S Li, S Wimberger, PP Hsieh, D Degtev, B Bestas, ... Nature Communications 13 (1), 1240, 2022 | 36 | 2022 |
| An optimized genome-wide, virus-free CRISPR screen for mammalian cells K Xiong, KJ la Cour Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ... Cell Reports Methods 1 (4), 2021 | 29 | 2021 |
| A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes KJ la Cour Karottki, H Hefzi, S Li, LE Pedersen, PN Spahn, C Joshi, ... Metabolic engineering 66, 114-122, 2021 | 26 | 2021 |
| Increasing production yield of tyrosine and mevalonate through inhibition of biomass formation S Li, CB Jendresen, AT Nielsen Process Biochemistry 51 (12), 1992-2000, 2016 | 25 | 2016 |
| CRISPR/Cas9-based genome editing for simultaneous interference with gene expression and protein stability V Martínez, I Lauritsen, T Hobel, S Li, AT Nielsen, MHH Nørholm Nucleic acids research 45 (20), e171-e171, 2017 | 24 | 2017 |
| A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo B Bestas, S Wimberger, D Degtev, A Madsen, AK Rottner, F Karlsson, ... Nature Communications 14 (1), 5474, 2023 | 10 | 2023 |
| A Consensus genomescale reconstruction of Chinese hamster ovary cell metabolism. Cell Syst 3 (5): 434-443. e8 H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... | 7 | 2016 |
| A Systematic Evaluation of Methods for Tailoring Genome-Scale Metabolic Models. Cell Syst. 2017; 4: 318–329. e6 S Opdam, A Richelle, B Kellman, S Li, DC Zielinski, NE Lewis | 7 | |
| A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism. Cell Syst. 3, 434–443 e8 H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ... | 6 | 2016 |
| A systematic evaluation of methods for tailoring genome-scale metabolic models. Cell systems. 2017; 4 (3): 318–329 S Opdam, A Richelle, B Kellman, S Li, DC Zielinski, NE Lewis | 6 | |
| Using targeted genome integration for virus-free genome-wide mammalian CRISPR screen K Xiong, KJC Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ... bioRxiv, 2020.05. 19.103648, 2020 | 2 | 2020 |
| Methods for decoupling cell growth from production of biochemicals and recombinant polypeptides S Li, CB Jendresen, LE Pedersen, J Landberg, KB Falkenberg, ... US Patent App. 16/321,131, 2019 | 1 | 2019 |
| CRISPRi-mediated metabolic switch enables concurrent aerobic and synthetic anaerobic fermentations in engineered consortium Y Rong, A Frey, E Özdemir, A Sainz de la Maza Larrea, S Li, AT Nielsen, ... Nature Communications 15 (1), 8985, 2024 | | 2024 |
| A Universal Method to Enrich Therapeutic Relevant Cells with Precise Genome Editing In Vitro and In Vivo S Li, N Akrap, S Cerboni, G Sienski, M Porritt, LS Pane, MA Coelho, ... MOLECULAR THERAPY 28 (4), 447-447, 2020 | | 2020 |
