Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism SB Prusiner, AL Woerman, DA Mordes, JC Watts, R Rampersaud, ... Proceedings of the National Academy of Sciences 112 (38), E5308-E5317, 2015 | 782 | 2015 |
Transmission of multiple system atrophy prions to transgenic mice JC Watts, K Giles, A Oehler, L Middleton, DT Dexter, SM Gentleman, ... Proceedings of the National Academy of Sciences 110 (48), 19555-19560, 2013 | 467 | 2013 |
Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions J Stöhr, JC Watts, ZL Mensinger, A Oehler, SK Grillo, SJ DeArmond, ... Proceedings of the National Academy of Sciences, 2012 | 452 | 2012 |
Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients JC Watts, C Condello, J Stöhr, A Oehler, J Lee, SJ DeArmond, L Lannfelt, ... Proceedings of the National Academy of Sciences 111 (28), 10323-10328, 2014 | 335 | 2014 |
α-Synuclein strains target distinct brain regions and cell types A Lau, RWL So, HHC Lau, JC Sang, A Ruiz-Riquelme, SC Fleck, E Stuart, ... Nature neuroscience 23 (1), 21-31, 2020 | 277 | 2020 |
Propagation of prions causing synucleinopathies in cultured cells AL Woerman, J Stöhr, A Aoyagi, R Rampersaud, Z Krejciova, JC Watts, ... Proceedings of the National Academy of Sciences 112 (35), E4949-E4958, 2015 | 263 | 2015 |
The in vivo brain interactome of the amyloid precursor protein Y Bai, K Markham, F Chen, R Weerasekera, J Watts, P Horne, Y Wakutani, ... Molecular & Cellular Proteomics 7 (1), 15-34, 2008 | 213 | 2008 |
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice J Stöhr, C Condello, JC Watts, L Bloch, A Oehler, M Nick, SJ DeArmond, ... Proceedings of the National Academy of Sciences 111 (28), 10329-10334, 2014 | 201 | 2014 |
α-Synuclein-based animal models of Parkinson's disease: challenges and opportunities in a new era NP Visanji, JM Brotchie, LV Kalia, JB Koprich, A Tandon, JC Watts, ... Trends in neurosciences 39 (11), 750-762, 2016 | 190 | 2016 |
The expanding universe of prion diseases JC Watts, A Balachandran, D Westaway PLoS pathogens 2 (3), e26, 2006 | 182 | 2006 |
The CNS glycoprotein Shadoo has PrPC‐like protective properties and displays reduced levels in prion infections JC Watts, B Drisaldi, V Ng, J Yang, B Strome, P Horne, MS Sy, L Yoong, ... The EMBO journal 26 (17), 4038-4050, 2007 | 179 | 2007 |
The prion protein family: diversity, rivalry, and dysfunction JC Watts, D Westaway Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1772 (6), 654-672, 2007 | 177 | 2007 |
Drug resistance confounding prion therapeutics DB Berry, D Lu, M Geva, JC Watts, S Bhardwaj, A Oehler, AR Renslo, ... Proceedings of the National Academy of Sciences 110 (44), E4160-E4169, 2013 | 165 | 2013 |
Evolutionary descent of prion genes from the ZIP family of metal ion transporters G Schmitt-Ulms, S Ehsani, JC Watts, D Westaway, H Wille PloS one 4 (9), e7208, 2009 | 152 | 2009 |
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease C Condello, T Lemmin, J Stöhr, M Nick, Y Wu, AM Maxwell, JC Watts, ... Proceedings of the National Academy of Sciences 115 (4), E782-E791, 2018 | 147 | 2018 |
Interactome Analyses Identify Ties of PrPC and Its Mammalian Paralogs to Oligomannosidic N-Glycans and Endoplasmic Reticulum-Derived Chaperones JC Watts, H Huo, Y Bai, S Ehsani, AH Won, T Shi, N Daude, A Lau, ... PLoS pathogens 5 (10), e1000608, 2009 | 145 | 2009 |
Evidence that bank vole PrP is a universal acceptor for prions JC Watts, K Giles, S Patel, A Oehler, SJ DeArmond, SB Prusiner PLoS pathogens 10 (4), e1003990, 2014 | 142 | 2014 |
Bioluminescence imaging of Aβ deposition in bigenic mouse models of Alzheimer's disease JC Watts, K Giles, SK Grillo, A Lemus, SJ DeArmond, SB Prusiner Proceedings of the National Academy of Sciences 108 (6), 2528-2533, 2011 | 121 | 2011 |
The function of the cellular prion protein in health and disease JC Watts, MEC Bourkas, H Arshad Acta neuropathologica 135, 159-178, 2018 | 110 | 2018 |
Mouse models for studying the formation and propagation of prions JC Watts, SB Prusiner Journal of Biological Chemistry 289 (29), 19841-19849, 2014 | 107 | 2014 |