Quenching protein dynamics interferes with HIV capsid maturation M Wang, CM Quinn, JR Perilla, H Zhang, R Shirra Jr, G Hou, IJ Byeon, ... Nature Communications 8 (1), 1779, 2017 | 67 | 2017 |
Ligand‐independent higher‐order multimerization of CXCR4, a G‐protein‐coupled chemokine receptor involved in targeted metastasis M Hamatake, T Aoki, Y Futahashi, E Urano, N Yamamoto, J Komano Cancer science 100 (1), 95-102, 2009 | 66 | 2009 |
Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene products W Nomura, H Aikawa, N Ohashi, E Urano, M Métifiot, M Fujino, K Maddali, ... ACS chemical biology 8 (10), 2235-2244, 2013 | 57 | 2013 |
Alkyl amine bevirimat derivatives are potent and broadly active HIV-1 maturation inhibitors E Urano, SD Ablan, R Mandt, GT Pauly, DM Sigano, JP Schneider, ... Antimicrobial agents and chemotherapy 60 (1), 190-197, 2016 | 55 | 2016 |
Cytokine signatures of transformed B cells with distinct Epstein–Barr virus latencies as a potential diagnostic tool for B cell lymphoma K Miyauchi, E Urano, H Yoshiyama, J Komano Cancer science 102 (6), 1236-1241, 2011 | 47 | 2011 |
Peptide HIV-1 integrase inhibitors from HIV-1 gene products S Suzuki, E Urano, C Hashimoto, H Tsutsumi, T Nakahara, T Tanaka, ... Journal of medicinal chemistry 53 (14), 5356-5360, 2010 | 46 | 2010 |
Corrigendum: A Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase in Inhibition Potency W Nomura, C Hashimoto, A Ohya, K Miyauchi, E Urano, T Tanaka, ... ChemMedChem 7 (4), 546, 2012 | 44 | 2012 |
Protein transduction by pseudotyped lentivirus-like nanoparticles T Aoki, K Miyauchi, E Urano, R Ichikawa, J Komano Gene Therapy 18 (9), 936-941, 2011 | 44 | 2011 |
Derivatives of 5-nitro-furan-2-carboxylic acid carbamoylmethyl ester inhibit RNase H activity associated with HIV-1 reverse transcriptase H Fuji, E Urano, Y Futahashi, M Hamatake, J Tatsumi, T Hoshino, ... Journal of medicinal chemistry 52 (5), 1380-1387, 2009 | 43 | 2009 |
A novel therapeutic molecule against HTLV-1 infection targeting provirus A Tanaka, S Takeda, R Kariya, K Matsuda, E Urano, S Okada, J Komano Leukemia 27 (8), 1621-1627, 2013 | 42 | 2013 |
Separate elements are required for ligand‐dependent and‐independent internalization of metastatic potentiator CXCR4 Y Futahashi, J Komano, E Urano, T Aoki, M Hamatake, K Miyauchi, ... Cancer science 98 (3), 373-379, 2007 | 39 | 2007 |
COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions E Urano, T Okamura, C Ono, S Ueno, S Nagata, H Kamada, M Higuchi, ... Proceedings of the National Academy of Sciences 118 (43), e2104847118, 2021 | 38 | 2021 |
Identification of an HIV-1 mutation in spacer peptide 1 that stabilizes the immature CA-SP1 lattice J Fontana, PW Keller, E Urano, SD Ablan, AC Steven, EO Freed Journal of Virology 90 (2), 972-978, 2016 | 38 | 2016 |
Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase H Yanagita, E Urano, K Matsumoto, R Ichikawa, Y Takaesu, M Ogata, ... Bioorganic & medicinal chemistry 19 (2), 816-825, 2011 | 35 | 2011 |
Substitution of the myristoylation signal of human immunodeficiency virus type 1 Pr55Gag with the phospholipase C-δ1 pleckstrin homology domain results in infectious … E Urano, T Aoki, Y Futahashi, T Murakami, Y Morikawa, N Yamamoto, ... Journal of general virology 89 (12), 3144-3149, 2008 | 35 | 2008 |
Resistance to second-generation HIV-1 maturation inhibitors E Urano, U Timilsina, JA Kaplan, S Ablan, D Ghimire, P Pham, N Kuruppu, ... Journal of virology 93 (6), 10.1128/jvi. 02017-18, 2019 | 30 | 2019 |
Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques T Nagatake, S Kishino, E Urano, H Murakami, N Kitamura, K Konishi, ... Mucosal Immunology 15 (2), 289-300, 2022 | 28 | 2022 |
Inhibiting lentiviral replication by HEXIM1, a cellular negative regulator of the CDK9/cyclin T complex S Shimizu, E Urano, Y Futahashi, K Miyauchi, M Isogai, Z Matsuda, ... Aids 21 (5), 575-582, 2007 | 28 | 2007 |
The interaction of HIV-1 with the host factors J Komano, Y Futahashi, E Urano, K Miyauchi, T Murakami, Z Matsuda, ... Japanese journal of infectious diseases 58 (3), 125-130, 2005 | 27 | 2005 |
Novel role of HSP40/DNAJ in the regulation of HIV-1 replication E Urano, Y Morikawa, J Komano JAIDS Journal of Acquired Immune Deficiency Syndromes 64 (2), 154-162, 2013 | 26 | 2013 |