| Evolution of genes and genomes on the Drosophila phylogeny AG Clark, MB Eisen, DR Smith, CM Bergman, B Oliver, TA Markow, ... Nature 450 (7167), 203-18, 2007 | 2289 | 2007 |
| Identifying a high fraction of the human genome to be under selective constraint using GERP++ EV Davydov, DL Goode, M Sirota, GM Cooper, A Sidow, S Batzoglou PLoS computational biology 6 (12), e1001025, 2010 | 1954 | 2010 |
| Ten years of pathway analysis: current approaches and outstanding challenges P Khatri, M Sirota, AJ Butte PLoS computational biology 8 (2), e1002375, 2012 | 1822 | 2012 |
| Systematic pan-cancer analysis of tumour purity D Aran, M Sirota, AJ Butte Nature communications 6 (1), 8971, 2015 | 1111 | 2015 |
| Discovery and preclinical validation of drug indications using compendia of public gene expression data M Sirota, JT Dudley, J Kim, AP Chiang, AA Morgan, A Sweet-Cordero, ... Science translational medicine 3 (96), 96ra77-96ra77, 2011 | 902 | 2011 |
| Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease JT Dudley, M Sirota, M Shenoy, RK Pai, S Roedder, AP Chiang, ... Science translational medicine 3 (96), 96ra76-96ra76, 2011 | 668 | 2011 |
| Comprehensive analysis of normal adjacent to tumor transcriptomes D Aran, R Camarda, J Odegaard, H Paik, B Oskotsky, G Krings, A Goga, ... Nature communications 8 (1), 1077, 2017 | 549 | 2017 |
| Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis A Palanichamy, L Apeltsin, TC Kuo, M Sirota, S Wang, SJ Pitts, ... Science translational medicine 6 (248), 248ra106-248ra106, 2014 | 266 | 2014 |
| B cell exchange across the blood-brain barrier in multiple sclerosis H von Büdingen, TC Kuo, M Sirota, CJ van Belle, L Apeltsin, J Glanville, ... The Journal of Clinical Investigation, 2012 | 262 | 2012 |
| Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association R Chen, EV Davydov, M Sirota, AJ Butte PloS one 5 (10), e13574, 2010 | 221 | 2010 |
| Cross-tissue analysis of gene and protein expression in normal and cancer tissues I Kosti, N Jain, D Aran, AJ Butte, M Sirota Scientific reports 6 (1), 24799, 2016 | 217 | 2016 |
| Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte Nature communications 8 (1), 16022, 2017 | 196 | 2017 |
| Autoimmune disease classification by inverse association with SNP alleles M Sirota, MA Schaub, S Batzoglou, WH Robinson, AJ Butte PLoS genetics 5 (12), e1000792, 2009 | 192 | 2009 |
| Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes K Kodama, M Horikoshi, K Toda, S Yamada, K Hara, J Irie, M Sirota, ... Proceedings of the National Academy of Sciences 109 (18), 7049-7054, 2012 | 188 | 2012 |
| Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy MS Ghaemi, DB DiGiulio, K Contrepois, B Callahan, TTM Ngo, ... Bioinformatics 35 (1), 95-103, 2019 | 175 | 2019 |
| dittoSeq: universal user-friendly single-cell and bulk RNA sequencing visualization toolkit DG Bunis, J Andrews, GK Fragiadakis, TD Burt, M Sirota Bioinformatics 36 (22-23), 5535-5536, 2020 | 150 | 2020 |
| The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions N Rahmioglu, S Mortlock, M Ghiasi, PL Møller, L Stefansdottir, ... Nature genetics 55 (3), 423-436, 2023 | 146 | 2023 |
| Mortality risk among patients with COVID-19 prescribed selective serotonin reuptake inhibitor antidepressants T Oskotsky, I Marić, A Tang, B Oskotsky, RJ Wong, N Aghaeepour, ... JAMA network open 4 (11), e2133090-e2133090, 2021 | 146 | 2021 |
| Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types K Yu, B Chen, D Aran, J Charalel, C Yau, DM Wolf, LJ Van ‘T Veer, ... Nature communications 10 (1), 3574, 2019 | 145 | 2019 |
| CONTRAST: a discriminative, phylogeny-free approach to multiple informant de novogene prediction SS Gross, CB Do, M Sirota, S Batzoglou Genome biology 8, 1-16, 2007 | 135 | 2007 |
Atul J. ButteDirector, Bakar Computational Health Sciences Institute, University of California, San FranciscoEmail verificata su ucsf.edu