| Highly efficient genome editing of murine and human hematopoietic progenitor cells by CRISPR/Cas9 MC Gundry, L Brunetti, A Lin, AE Mayle, A Kitano, D Wagner, JI Hsu, ... Cell reports 17 (5), 1453-1461, 2016 | 291 | 2016 |
| Mutant NPM1 maintains the leukemic state through HOX expression L Brunetti, MC Gundry, D Sorcini, AG Guzman, YH Huang, ... Cancer cell 34 (3), 499-512. e9, 2018 | 285 | 2018 |
| NPM1-mutated acute myeloid leukemia: from bench to bedside B Falini, L Brunetti, P Sportoletti, MP Martelli Blood, The Journal of the American Society of Hematology 136 (15), 1707-1721, 2020 | 269 | 2020 |
| DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A YH Huang, J Su, Y Lei, L Brunetti, MC Gundry, X Zhang, M Jeong, W Li, ... Genome biology 18, 1-11, 2017 | 236 | 2017 |
| Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells M Daher, R Basar, E Gokdemir, N Baran, N Uprety, AK Nunez Cortes, ... Blood, The Journal of the American Society of Hematology 137 (5), 624-636, 2021 | 229 | 2021 |
| DNMT3A in Leukemia L Brunetti, MC Gundry, MA Goodell Cold Spring Harbor perspectives in medicine 7 (2), a030320, 2017 | 208 | 2017 |
| Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells MP Martelli, I Gionfriddo, F Mezzasoma, F Milano, S Pierangeli, F Mulas, ... Blood, The Journal of the American Society of Hematology 125 (22), 3455-3465, 2015 | 169 | 2015 |
| CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression K Fousek, J Watanabe, SK Joseph, A George, X An, TT Byrd, JS Morris, ... Leukemia 35 (1), 75-89, 2021 | 155 | 2021 |
| CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice MP Martelli, V Pettirossi, C Thiede, E Bonifacio, F Mezzasoma, D Cecchini, ... Blood, The Journal of the American Society of Hematology 116 (19), 3907-3922, 2010 | 142 | 2010 |
| Aerobic plus resistance exercise in obese older adults improves muscle protein synthesis and preserves myocellular quality despite weight loss G Colleluori, L Aguirre, U Phadnis, K Fowler, R Armamento-Villareal, ... Cell metabolism 30 (2), 261-273. e6, 2019 | 125 | 2019 |
| Dactinomycin in NPM1-mutated acute myeloid leukemia B Falini, L Brunetti, MP Martelli New England Journal of Medicine 373 (12), 1180-1182, 2015 | 84 | 2015 |
| Nutrient‐sensitive transcription factors TFEB and TFE 3 couple autophagy and metabolism to the peripheral clock N Pastore, A Vainshtein, NJ Herz, T Huynh, L Brunetti, TJ Klisch, ... The EMBO journal 38 (12), e101347, 2019 | 77 | 2019 |
| Current status and future perspectives in targeted therapy of NPM1-mutated AML R Ranieri, G Pianigiani, S Sciabolacci, VM Perriello, A Marra, V Cardinali, ... Leukemia 36 (10), 2351-2367, 2022 | 74 | 2022 |
| Mutant NPM1 directly regulates oncogenic transcription in acute myeloid leukemia HJ Uckelmann, EL Haarer, R Takeda, EM Wong, C Hatton, C Marinaccio, ... Cancer discovery 13 (3), 746-765, 2023 | 73 | 2023 |
| CD200/OX2, a cell surface molecule with immuno-regulatory function, is consistently expressed on hairy cell leukaemia neoplastic cells L Brunetti, R Di Noto, G Abate, M Gorrese, A Gravetti, M Raia, G Scalia, ... British journal of haematology, 665-667, 2009 | 63 | 2009 |
| Actinomycin D targets NPM1c-primed mitochondria to restore PML-driven senescence in AML therapy HC Wu, D Rérolle, C Berthier, R Hleihel, T Sakamoto, S Quentin, ... Cancer discovery 11 (12), 3198-3213, 2021 | 61 | 2021 |
| How I diagnose and treat NPM1-mutated AML B Falini, L Brunetti, MP Martelli Blood, The Journal of the American Society of Hematology 137 (5), 589-599, 2021 | 58 | 2021 |
| Blastic plasmacytoid dendritic cell neoplasm and chronic myelomonocytic leukemia: a shared clonal origin L Brunetti, V Di Battista, A Venanzi, G Schiavoni, MP Martelli, S Ascani, ... Leukemia 31 (5), 1238-1240, 2017 | 54 | 2017 |
| Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics B Falini, P Sportoletti, L Brunetti, MP Martelli British journal of haematology 170 (3), 305-322, 2015 | 54 | 2015 |
| Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor YH Huang, CW Chen, V Sundaramurthy, M Słabicki, D Hao, CJ Watson, ... Cancer discovery 12 (1), 220-235, 2022 | 53 | 2022 |
Brunangelo FaliniProfessor of Hematology, University of Perugia, ItalyEmail verificata su unipg.it