Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin MYF Tay, JE Fraser, WKK Chan, NJ Moreland, AP Rathore, C Wang, ... Antiviral research 99 (3), 301-306, 2013 | 375 | 2013 |
Adaptive immune responses to primary and secondary dengue virus infections AL St. John, APS Rathore Nature Reviews Immunology 19 (4), 218-230, 2019 | 315 | 2019 |
Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial JG Low, C Sung, L Wijaya, Y Wei, APS Rathore, S Watanabe, BH Tan, ... The Lancet infectious diseases 14 (8), 706-715, 2014 | 263 | 2014 |
Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance AL St. John, APS Rathore, H Yap, ML Ng, DD Metcalfe, SG Vasudevan, ... Proceedings of the National Academy of Sciences 108 (22), 9190-9195, 2011 | 262 | 2011 |
Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage AL St John, APS Rathore, B Raghavan, ML Ng, SN Abraham elife 2, e00481, 2013 | 200 | 2013 |
Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model APS Rathore, PN Paradkar, S Watanabe, KH Tan, C Sung, JE Connolly, ... Antiviral research 92 (3), 453-460, 2011 | 197 | 2011 |
Cross-reactive immunity among flaviviruses APS Rathore, AL St. John Frontiers in immunology 11, 334, 2020 | 168 | 2020 |
Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation APS Rathore, ML Ng, SG Vasudevan Virology journal 10, 1-15, 2013 | 125 | 2013 |
Maternal immunity and antibodies to dengue virus promote infection and Zika virus–induced microcephaly in fetuses APS Rathore, WAA Saron, T Lim, N Jahan, AL St. John Science Advances 5 (2), eaav3208, 2019 | 122 | 2019 |
Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo APS Rathore, T Haystead, PK Das, A Merits, ML Ng, SG Vasudevan Antiviral research 103, 7-16, 2014 | 117 | 2014 |
Dose-and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial S Watanabe, APS Rathore, C Sung, F Lu, YM Khoo, J Connolly, J Low, ... Antiviral research 96 (1), 32-35, 2012 | 108 | 2012 |
Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE R Msallam, J Balla, APS Rathore, H Kared, B Malleret, WAA Saron, Z Liu, ... Science 370 (6519), 941-950, 2020 | 103 | 2020 |
Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells WAA Saron, APS Rathore, L Ting, EE Ooi, J Low, SN Abraham, ... Science advances 4 (7), eaar4297, 2018 | 88 | 2018 |
Dengue virus–elicited tryptase induces endothelial permeability and shock APS Rathore, CK Mantri, SAB Aman, A Syenina, J Ooi, CJ Jagaraj, ... The Journal of clinical investigation 129 (10), 4180-4193, 2019 | 85 | 2019 |
Japanese encephalitis virus neuropenetrance is driven by mast cell chymase JT Hsieh, APS Rathore, G Soundarajan, AL St. John Nature communications 10 (1), 706, 2019 | 82 | 2019 |
The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model S Watanabe, KH Tan, APS Rathore, K Rozen-Gagnon, W Shuai, C Ruedl, ... Journal of virology 86 (10), 5508-5514, 2012 | 78 | 2012 |
Dengue: update on clinically relevant therapeutic strategies and vaccines M Palanichamy Kala, AL St. John, APS Rathore Current Treatment Options in Infectious Diseases 15 (2), 27-52, 2023 | 74 | 2023 |
New perspectives on the origins and heterogeneity of mast cells AL St. John, APS Rathore, F Ginhoux Nature Reviews Immunology 23 (1), 55-68, 2023 | 74 | 2023 |
Early insights into immune responses during COVID-19 AL St John, APS Rathore The Journal of Immunology 205 (3), 555-564, 2020 | 69 | 2020 |
Chymase level is a predictive biomarker of dengue hemorrhagic fever in pediatric and adult patients H Tissera, APS Rathore, WY Leong, BL Pike, TE Warkentien, FS Farouk, ... The Journal of infectious diseases 216 (9), 1112-1121, 2017 | 67 | 2017 |