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Eric Conway
Eric Conway
School of Biomolecular and Biomedical Sciences, University College Dublin
Email verificata su ucd.ie - Home page
Titolo
Citata da
Citata da
Anno
Histone H2AK119 mono-ubiquitination is essential for polycomb-mediated transcriptional repression
S Tamburri, E Lavarone, D Fernández-Pérez, E Conway, M Zanotti, ...
Molecular cell 77 (4), 840-856. e5, 2020
3192020
PRC2 mediated H3K27 methylations in cellular identity and cancer
E Conway, E Healy, AP Bracken
Current opinion in cell biology 37, 42-48, 2015
2392015
The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells
G Streubel, A Watson, SG Jammula, A Scelfo, DJ Fitzpatrick, G Oliviero, ...
Molecular cell 70 (2), 371-379. e5, 2018
1782018
PRC2. 1 and PRC2. 2 synergize to coordinate H3K27 trimethylation
E Healy, M Mucha, E Glancy, DJ Fitzpatrick, E Conway, HK Neikes, ...
Molecular cell 76 (3), 437-452. e6, 2019
1762019
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ...
Molecular cell 70 (3), 408-421. e8, 2018
1562018
BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
E Conway, F Rossi, D Fernandez-Perez, E Ponzo, KJ Ferrari, M Zanotti, ...
Molecular cell 81 (17), 3526-3541. e8, 2021
832021
Polycomb-dependent histone H2A ubiquitination links developmental disorders with cancer
S Tamburri, E Conway, D Pasini
Trends in Genetics 38 (4), 333-352, 2022
432022
A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence
GL Brien, E Healy, E Jerman, E Conway, E Fadda, D O'Donovan, ...
Genes & development 29 (21), 2231-2243, 2015
422015
Unraveling the Roles of Canonical and Noncanonical PRC1 Complexes
EM Conway, AP Bracken
Polycomb Group Proteins, 57-80, 2017
92017
Know when to fold ‘em: Polycomb complexes in oncogenic 3D genome regulation
EJ Doyle, L Morey, E Conway
Frontiers in cell and developmental biology 10, 986319, 2022
52022
Dominant negative and directional dysregulation of Polycomb function in EZH2-mutant human growth disorders
O Deevy, C Monger, F Matrà, E Tuck, E Conway, S Rodighiero, Q Zhang, ...
bioRxiv, 2023
32023
Dominant negative effects on H3K27 methylation by Weaver syndrome-associated EZH2 variants
O Deevy, C Monger, F Matrà, E Tuck, E Conway, M Badonyi, D Nimmo, ...
bioRxiv, 2023.06. 01.543208, 2023
12023
BAP1 activity regulates PcG occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition
E Conway, F Rossi, S Tamburri, E Ponzo, KJ Ferrari, M Zanotti, ...
Biorxiv, 2020.12. 10.419309, 2020
12020
Editorial overview: 3D Genome Chromatin organization and regulation
E Conway, DR Larson
Current Opinion in Structural Biology 90, 102956, 2025
2025
A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells
R McCole, J Nolan, DM Reck, C Monger, S Rustichelli, E Conway, ...
Cell Reports 44 (1), 115192, 2025
2025
Short circuit: Transcription factor addiction as a growing vulnerability in cancer
M Davies, M Boyce, E Conway
Current Opinion in Structural Biology 89, 102948, 2024
2024
A Novel Form of AEBP2-Containing PRC2. 2 Is a Genetic Dependency in Germinal Centre B-Cell Lymphoma and Its Targeting Can Overcome Acquired Resistance to EZH2 Inhibition
J Nolan, D Angelov, D Nimmo, G Holland, M Davies, E Dillon, D Reck, ...
Blood 144, 4121, 2024
2024
EZH1-PRC2 Identifies a Potential Reservoir for Disease Relapse in Quiescent Cancer Cells Refractory to EZH2 Enzymatic Inhibition
E Healy, R McCole, C Monger, J Nolan, E Conway, G Brien, C Wang, ...
Blood 140 (Supplement 1), 3049-3050, 2022
2022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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