Neuronal hyperactivity disturbs ATP microgradients, impairs microglial motility, and reduces phagocytic receptor expression triggering apoptosis/microglial phagocytosis uncoupling O Abiega, S Beccari, I Diaz-Aparicio, A Nadjar, S Layé, Q Leyrolle, ... PLoS biology 14 (5), e1002466, 2016 | 222 | 2016 |
Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients J Rodriguez, S Hiel, AM Neyrinck, T Le Roy, SA Pötgens, Q Leyrolle, ... Gut 69 (11), 1975-1987, 2020 | 202 | 2020 |
Microbiota-derived metabolites as drivers of gut–brain communication H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen, S Layé, N Delzenne, ... Gut microbes 14 (1), 2102878, 2022 | 192 | 2022 |
Neuroinflammation in autism: plausible role of maternal inflammation, dietary omega 3, and microbiota C Madore, Q Leyrolle, C Lacabanne, A Benmamar-Badel, C Joffre, ... Neural plasticity 2016 (1), 3597209, 2016 | 163 | 2016 |
Gut microbiota-induced changes in β-hydroxybutyrate metabolism are linked to altered sociability and depression in alcohol use disorder S Leclercq, T Le Roy, S Furgiuele, V Coste, LB Bindels, Q Leyrolle, ... Cell Reports 33 (2), 2020 | 139 | 2020 |
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain C Madore, Q Leyrolle, L Morel, M Rossitto, AD Greenhalgh, JC Delpech, ... Nature communications 11 (1), 6133, 2020 | 135 | 2020 |
Link between gut microbiota and health outcomes in inulin-treated obese patients: Lessons from the Food4Gut multicenter randomized placebo-controlled trial S Hiel, MA Gianfrancesco, J Rodriguez, D Portheault, Q Leyrolle, ... Clinical Nutrition 39 (12), 3618-3628, 2020 | 132 | 2020 |
Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation VF Labrousse, Q Leyrolle, C Amadieu, A Aubert, A Séré, E Coutureau, ... Brain, behavior, and immunity 73, 427-440, 2018 | 91 | 2018 |
Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: a cross-sectional study in obese patients Q Leyrolle, R Cserjesi, MDGH Mulders, G Zamariola, S Hiel, ... Clinical nutrition 40 (4), 2035-2044, 2021 | 57 | 2021 |
Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: a randomized, controlled trial Q Leyrolle, R Cserjesi, MDGH Mulders, G Zamariola, S Hiel, ... Brain, behavior, and immunity 94, 289-298, 2021 | 56 | 2021 |
Bioactive lipids as new class of microglial modulators: When nutrition meets neuroimunology A Nadjar, Q Leyrolle, C Joffre, S Laye Progress in Neuro-Psychopharmacology and Biological Psychiatry 79, 19-26, 2017 | 44 | 2017 |
Hepatoprotective effects of indole, a gut microbial metabolite, in leptin-deficient obese mice C Knudsen, AM Neyrinck, Q Leyrolle, P Baldin, S Leclercq, J Rodriguez, ... The Journal of nutrition 151 (6), 1507-1516, 2021 | 40 | 2021 |
Direct and indirect effects of lipids on microglia function Q Leyrolle, S Laye, A Nadjar Neuroscience Letters 708, 134348, 2019 | 37 | 2019 |
Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients C Amadieu, V Coste, AM Neyrinck, V Thijssen, Q Leyrolle, LB Bindels, ... Gut Microbes 14 (1), 2007042, 2022 | 32 | 2022 |
Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime Q Leyrolle, F Decoeur, G Briere, C Amadieu, ARAA Quadros, I Voytyuk, ... Neuropsychopharmacology 46 (3), 579-602, 2021 | 26 | 2021 |
N‐3 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development Q Leyrolle, F Decoeur, C Dejean, G Brière, S Leon, I Bakoyiannis, ... Glia 70 (1), 50-70, 2022 | 25 | 2022 |
Microglial cannabinoid type 1 receptor regulates brain inflammation in a sex-specific manner J De Meij, Z Alfanek, L Morel, F Decoeur, Q Leyrolle, K Picard, M Carrier, ... Cannabis and Cannabinoid Research 6 (6), 488-507, 2021 | 25 | 2021 |
Dietary N-3 PUFA deficiency affects sleep-wake activity in basal condition and in response to an inflammatory challenge in mice F Decoeur, A Benmamar-Badel, Q Leyrolle, M Persillet, S Layé, A Nadjar Brain, behavior, and immunity 85, 162-169, 2020 | 20 | 2020 |
Correction: neuronal hyperactivity disturbs ATP microgradients, impairs microglial motility, and reduces phagocytic receptor expression triggering apoptosis/microglial … O Abiega, S Beccari, I Diaz-Aparicio, A Nadjar, S Layé, Q Leyrolle, ... PLoS biology 14 (6), e1002508, 2016 | 11 | 2016 |
Dietary marine hydrolysate improves memory performance and social behavior through gut microbiota remodeling during aging C Mougin, M Chataigner, C Lucas, Q Leyrolle, V Pallet, S Layé, E Bouvret, ... Foods 12 (23), 4199, 2023 | 8 | 2023 |