Role of transforming growth factor-β signaling in cancer MP de Caestecker, E Piek, AB Roberts Journal of the National Cancer Institute 92 (17), 1388-1402, 2000 | 712 | 2000 |
The transforming growth factor-β superfamily of receptors M De Caestecker Cytokine & growth factor reviews 15 (1), 1-11, 2004 | 690 | 2004 |
Cross‐talk between ERK MAP kinase and Smad‐signaling pathways enhances TGF‐β dependent responses in human mesangial cells T Hayashida, M de Caestecker, HW Schnaper The FASEB journal 17 (11), 1-21, 2003 | 488 | 2003 |
Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases MP De Caestecker, WT Parks, CJ Frank, P Castagnino, DP Bottaro, ... Genes & development 12 (11), 1587-1592, 1998 | 366 | 1998 |
Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-β-induced aggrecan gene expression in … H Watanabe, MP de Caestecker, Y Yamada Journal of Biological Chemistry 276 (17), 14466-14473, 2001 | 357 | 2001 |
A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif S Larisch, Y Yi, R Lotan, H Kerner, S Eimerl, W Tony Parks, Y Gottfried, ... Nature cell biology 2 (12), 915-921, 2000 | 337 | 2000 |
Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia S Boyle, A Misfeldt, KJ Chandler, KK Deal, EM Southard-Smith, ... Developmental biology 313 (1), 234-245, 2008 | 316 | 2008 |
Structural basis of heteromeric smad protein assembly in TGF-β signaling BM Chacko, BY Qin, A Tiwari, G Shi, S Lam, LJ Hayward, ... Molecular cell 15 (5), 813-823, 2004 | 276 | 2004 |
The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain MP De Caestecker, T Yahata, D Wang, WT Parks, S Huang, CS Hill, ... Journal of Biological Chemistry 275 (3), 2115-2122, 2000 | 247 | 2000 |
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization BM Chacko, B Qin, JJ Correia, SS Lam, MP de Caestecker, K Lin Nature structural biology 8 (3), 248-253, 2001 | 237 | 2001 |
Renal bone morphogenetic protein-7 protects against diabetic nephropathy S Wang, M de Caestecker, J Kopp, G Mitu, J LaPage, R Hirschberg Journal of the American Society of Nephrology 17 (9), 2504-2512, 2006 | 234 | 2006 |
Clinical use of the urine biomarker [TIMP-2]×[IGFBP7] for acute kidney injury risk assessment A Vijayan, S Faubel, DJ Askenazi, J Cerda, WH Fissell, M Heung, ... American Journal of Kidney Diseases 68 (1), 19-28, 2016 | 225 | 2016 |
Characterization of functional domains within Smad4/DPC4 MP de Caestecker, P Hemmati, S Larisch-Bloch, R Ajmera, AB Roberts, ... Journal of Biological Chemistry 272 (21), 13690-13696, 1997 | 211 | 1997 |
SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor β L Vindevoghel, RJ Lechleider, A Kon, MP De Caestecker, J Uitto, ... Proceedings of the National Academy of Sciences 95 (25), 14769-14774, 1998 | 203 | 1998 |
The transforming growth factor-βbgr/SMAD signaling pathway is present and functional in human mesangial cells AC Poncelet, MP De Caestecker, HW Schnaper Kidney international 56 (4), 1354-1365, 1999 | 202 | 1999 |
Histone deacetylase inhibitor enhances recovery after AKI CC Cosentino, NI Skrypnyk, LL Brilli, T Chiba, T Novitskaya, C Woods, ... Journal of the American Society of Nephrology 24 (6), 943-953, 2013 | 199 | 2013 |
The hepatitis B virus encoded oncoprotein pX amplifies TGF-β family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis DK Lee, SH Park, Y Yi, SG Choi, C Lee, WT Parks, HS Cho, ... Genes & development 15 (4), 455-466, 2001 | 199 | 2001 |
A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-β signal transduction RH Kim, D Wang, M Tsang, J Martin, C Huff, MP De Caestecker, WT Parks, ... Genes & development 14 (13), 1605-1616, 2000 | 198 | 2000 |
BMP signaling in vascular development and disease JW Lowery, MP de Caestecker Cytokine & growth factor reviews 21 (4), 287-298, 2010 | 196 | 2010 |
Bone morphogenetic protein 4 promotes pulmonary vascular remodeling in hypoxic pulmonary hypertension DB Frank, A Abtahi, DJ Yamaguchi, S Manning, Y Shyr, A Pozzi, ... Circulation research 97 (5), 496-504, 2005 | 183 | 2005 |