Shikonin derivatives for cancer prevention and therapy JC Boulos, M Rahama, MEF Hegazy, T Efferth Cancer letters 459, 248-267, 2019 | 180 | 2019 |
Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells MEM Saeed, JC Boulos, G Elhaboub, D Rigano, A Saab, MR Loizzo, ... Phytomedicine 62, 152945, 2019 | 52 | 2019 |
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways HE Daaboul, CF Daher, K Bodman-Smith, RI Taleb, WN Shebaby, ... Chemico-Biological Interactions 275, 162-170, 2017 | 34 | 2017 |
Investigation of cancer drug resistance mechanisms by phosphoproteomics JC Boulos, MRY Idres, T Efferth Pharmacological Research 160, 105091, 2020 | 28 | 2020 |
β-2-himachalen-6-ol: A novel anticancer sesquiterpene unique to the Lebanese wild carrot RI Taleb, P Najm, W Shebaby, JC Boulos, S Demirdjian, E Hariri, ... Journal of ethnopharmacology 190, 59-67, 2016 | 27 | 2016 |
Nanocarriers to enhance solubility, bioavailability, and efficacy of artemisinins AR Bilia, MC Bergonzi, JC Boulos, T Efferth World Journal of Traditional Chinese Medicine 6 (1), 26-36, 2020 | 23 | 2020 |
Repurposing of the ALK inhibitor crizotinib for acute leukemia and multiple myeloma cells JC Boulos, MEM Saeed, M Chatterjee, Y Bülbül, F Crudo, D Marko, ... Pharmaceuticals 14 (11), 1126, 2021 | 18 | 2021 |
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma JC Boulos, EA Omer, D Rigano, C Formisano, M Chatterjee, E Leich, ... Acta Pharmacologica Sinica 44 (11), 2265-2281, 2023 | 15 | 2023 |
Expression of the stem cell marker ABCB5 in normal and tumor tissues MEM Saeed, JC Boulos, K Machel, N Andabili, T Marouni, W Roth, ... in vivo 36 (4), 1651-1666, 2022 | 15 | 2022 |
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo HE Daaboul, CF Daher, RI Taleb, J Boulos, K Bodman-Smith, P Boukamp, ... Journal of Pharmacy and Pharmacology 69 (11), 1552-1564, 2017 | 15 | 2017 |
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells M Zhou, JC Boulos, SM Klauck, T Efferth Cell Biology and Toxicology 39 (6), 2971-2997, 2023 | 14 | 2023 |
The Wild Carrot (Daucus carota): A Phytochemical and Pharmacological Review J Ismail, WN Shebaby, J Daher, JC Boulos, R Taleb, CF Daher, M Mroueh Plants 13 (1), 93, 2023 | 11 | 2023 |
Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo LJ Rashan, N Özenver, JC Boulos, M Dawood, WP Roos, K Franke, ... Molecules 28 (4), 1871, 2023 | 11 | 2023 |
Activity of Cordycepin From Cordyceps sinensis Against Drug-Resistant Tumor Cells as Determined by Gene Expression and Drug Sensitivity Profiling N Özenver, JC Boulos, T Efferth Natural Product Communications 16 (2), 1934578X21993350, 2021 | 10 | 2021 |
Modes of action of a novel c-myc inhibiting 1, 2, 4-oxadiazole derivative in leukemia and breast cancer cells M Zhou, JC Boulos, EA Omer, SM Klauck, T Efferth Molecules 28 (15), 5658, 2023 | 8 | 2023 |
Disruption of lipid raft microdomains, regulation of CD38, TP53, and MYC signaling, and induction of apoptosis by lomitapide in multiple myeloma cells MEM Saeed, JC Boulos, SB Muecklich, E Leich, M Chatterjee, SM Klauck, ... Cancer genomics & proteomics 19 (5), 540-555, 2022 | 8 | 2022 |
F., Efferth T.(2019) JC Boulos, M Rahama, ME Hegazy Shikonin derivatives for cancer prevention and therapy. Cancer Lett 459, 248-267, 0 | 7 | |
Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM … M Zhou, JC Boulos, EA Omer, HA Rudbari, T Schirmeister, N Micale, ... European Journal of Pharmacology 956, 175980, 2023 | 6 | 2023 |
In silico, in vitro, and in vivo investigations on adapalene as repurposed third generation retinoid against multiple myeloma and leukemia JC Boulos, M Chatterjee, L Shan, T Efferth Cancers 15 (16), 4136, 2023 | 6 | 2023 |
Identification of gedunin from a phytochemical depository as a novel multidrug resistance-bypassing tubulin inhibitor of cancer cells SA Khalid, M Dawood, JC Boulos, M Wasfi, A Drif, F Bahramimehr, ... Molecules 27 (18), 5858, 2022 | 6 | 2022 |