| OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006 | 1591 | 2006 |
| Symbiotic gut microbes modulate human metabolic phenotypes M Li, B Wang, M Zhang, M Rantalainen, S Wang, H Zhou, Y Zhang, ... Proceedings of the National Academy of Sciences 105 (6), 2117-2122, 2008 | 1390 | 2008 |
| Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis AM Georgoudaki, KE Prokopec, VF Boura, E Hellqvist, S Sohn, J Östling, ... Cell reports 15 (9), 2000-2011, 2016 | 577 | 2016 |
| Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study P Ström, K Kartasalo, H Olsson, L Solorzano, B Delahunt, DM Berney, ... The Lancet Oncology 21 (2), 222-232, 2020 | 560 | 2020 |
| Artificial intelligence as the next step towards precision pathology B Acs, M Rantalainen, J Hartman Journal of internal medicine 288 (1), 62-81, 2020 | 420 | 2020 |
| Top-Down Systems Biology Modeling of Host Metabotype− Microbiome Associations in Obese Rodents A Waldram, E Holmes, Y Wang, M Rantalainen, ID Wilson, KM Tuohy, ... Journal of proteome research 8 (5), 2361-2375, 2009 | 303 | 2009 |
| Digital image analysis outperforms manual biomarker assessment in breast cancer G Stålhammar, NF Martinez, M Lippert, NP Tobin, I Mølholm, L Kis, ... Modern Pathology 29 (4), 318-329, 2016 | 208 | 2016 |
| Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice M Rantalainen, O Cloarec, O Beckonert, ID Wilson, D Jackson, R Tonge, ... Journal of proteome research 5 (10), 2642-2655, 2006 | 185 | 2006 |
| Human metabolic profiles are stably controlled by genetic and environmental variation G Nicholson, M Rantalainen, AD Maher, JV Li, D Malmodin, KR Ahmadi, ... Molecular systems biology 7 (1), 525, 2011 | 175 | 2011 |
| Beta-Poisson model for single-cell RNA-seq data analyses TN Vu, QF Wills, KR Kalari, N Niu, L Wang, M Rantalainen, Y Pawitan Bioinformatics 32 (14), 2128-2135, 2016 | 171 | 2016 |
| TP53 outperforms other androgen receptor biomarkers to predict abiraterone or enzalutamide outcome in metastatic castration-resistant prostate cancer B De Laere, S Oeyen, M Mayrhofer, T Whitington, PJ van Dam, ... Clinical Cancer Research 25 (6), 1766-1773, 2019 | 165 | 2019 |
| Improved breast cancer histological grading using deep learning Y Wang, B Acs, S Robertson, B Liu, L Solorzano, C Wählby, J Hartman, ... Annals of Oncology 33 (1), 89-98, 2022 | 156 | 2022 |
| A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection G Nicholson, M Rantalainen, JV Li, AD Maher, D Malmodin, KR Ahmadi, ... PLoS genetics 7 (9), e1002270, 2011 | 142 | 2011 |
| The metabonomics of aging and development in the rat: an investigation into the effect of age on the profile of endogenous metabolites in the urine of male rats using 1H NMR … RE Williams, EM Lenz, JS Lowden, M Rantalainen, ID Wilson Molecular BioSystems 1 (2), 166-175, 2005 | 140 | 2005 |
| Assessment of breast cancer risk factors reveals subtype heterogeneity J Holm, L Eriksson, A Ploner, M Eriksson, M Rantalainen, J Li, P Hall, ... Cancer research 77 (13), 3708-3717, 2017 | 131 | 2017 |
| Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis M Mayrhofer, B De Laere, T Whitington, P Van Oyen, C Ghysel, J Ampe, ... Genome medicine 10 (1), 1-13, 2018 | 130 | 2018 |
| K-OPLS package: kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space M Bylesjö, M Rantalainen, JK Nicholson, E Holmes, J Trygg BMC bioinformatics 9 (1), 1-7, 2008 | 110 | 2008 |
| The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue AW Drong, G Nicholson, ÅK Hedman, E Meduri, E Grundberg, KS Small, ... PLoS One 8 (2), e55923, 2013 | 105 | 2013 |
| Digital image analysis of Ki67 in hot spots is superior to both manual Ki67 and mitotic counts in breast cancer G Stålhammar, S Robertson, L Wedlund, M Lippert, M Rantalainen, ... Histopathology 72 (6), 974-989, 2018 | 99 | 2018 |
| Statistical correlation and projection methods for improved information recovery from diffusion-edited NMR spectra of biological samples LM Smith, AD Maher, O Cloarec, M Rantalainen, H Tang, P Elliott, ... Analytical chemistry 79 (15), 5682-5689, 2007 | 97 | 2007 |