| Chemotherapy-resistant human acute myeloid leukemia cells are not enriched for leukemic stem cells but require oxidative metabolism T Farge, E Saland, F De Toni, N Aroua, M Hosseini, R Perry, C Bosc, ... Cancer discovery 7 (7), 716-735, 2017 | 804 | 2017 |
| High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells L Poulain, P Sujobert, F Zylbersztejn, S Barreau, L Stuani, M Lambert, ... Leukemia 31 (11), 2326-2335, 2017 | 145 | 2017 |
| Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia L Stuani, M Sabatier, E Saland, G Cognet, N Poupin, C Bosc, FA Castelli, ... Journal of Experimental Medicine 218 (5), e20200924, 2021 | 91 | 2021 |
| Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia H Boutzen, E Saland, C Larrue, F De Toni, L Gales, FA Castelli, ... Journal of Experimental Medicine 213 (4), 483-497, 2016 | 87 | 2016 |
| Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia C Bosc, E Saland, A Bousard, N Gadaud, M Sabatier, G Cognet, T Farge, ... Nature cancer 2 (11), 1204-1223, 2021 | 78 | 2021 |
| Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia N Aroua, E Boet, M Ghisi, ML Nicolau-Travers, E Saland, R Gwilliam, ... Cancer Discovery 10 (10), 1544-1565, 2020 | 72 | 2020 |
| Stable isotope labeling highlights enhanced fatty acid and lipid metabolism in human acute myeloid leukemia L Stuani, F Riols, P Millard, M Sabatier, A Batut, E Saland, F Viars, ... International Journal of Molecular Sciences 19 (11), 3325, 2018 | 65 | 2018 |
| Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia L Stuani, M Sabatier, JE Sarry BMC biology 17 (1), 57, 2019 | 57 | 2019 |
| Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells C Larrue, N Guiraud, PL Mouchel, M Dubois, T Farge, M Gotanègre, ... Nature communications 12 (1), 422, 2021 | 51 | 2021 |
| C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3-Mutant Leukemia M Sabatier, R Birsen, L Lauture, S Mouche, P Angelino, J Dehairs, ... Cancer Discovery 13 (7), 1720-1747, 2023 | 47 | 2023 |
| Inosine induces stemness features in CAR-T cells and enhances potency DD Klysz, C Fowler, M Malipatlolla, L Stuani, KA Freitas, Y Chen, S Meier, ... Cancer Cell 42 (2), 266-282. e8, 2024 | 40 | 2024 |
| AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia A Grenier, L Poulain, J Mondesir, A Jacquel, C Bosc, L Stuani, S Mouche, ... Cell Reports 38 (1), 2022 | 36 | 2022 |
| Novel metabolic features in Acinetobacter baylyi ADP1 revealed by a multiomics approach L Stuani, C Lechaplais, AV Salminen, B Ségurens, M Durot, V Castelli, ... Metabolomics 10 (6), 1223-1238, 2014 | 34 | 2014 |
| CD36 drives metastasis and relapse in acute myeloid leukemia T Farge, J Nakhle, D Lagarde, G Cognet, N Polley, R Castellano, ... Cancer Research 83 (17), 2824-2838, 2023 | 33 | 2023 |
| Activation of vitamin D receptor pathway enhances differentiating capacity in acute myeloid leukemia with isocitrate dehydrogenase mutations M Sabatier, E Boet, S Zaghdoudi, N Guiraud, A Hucteau, N Polley, ... Cancers 13 (20), 5243, 2021 | 11 | 2021 |
| De novo structure determination of 3-((3-aminopropyl)amino)-4-hydroxybenzoic acid, a novel and abundant metabolite in Acinetobacter baylyi ADP1 M Thomas, L Stuani, E Darii, C Lechaplais, E Pateau, JC Tabet, ... Metabolomics 15, 1-13, 2019 | 6 | 2019 |
| GLUT1 overexpression in CAR-T cells induces metabolic reprogramming and enhances potency JA Guerrero, DD Klysz, Y Chen, M Malipatlolla, J Lone, C Fowler, L Stuani, ... Nature Communications 15 (1), 8658, 2024 | 5 | 2024 |
| Help from outside: cysteine to survive in AML L Stuani, JE Sarry Blood, The Journal of the American Society of Hematology 134 (4), 336-338, 2019 | 5 | 2019 |
| Microenvironmental aspartate preserves leukemic cells from therapy-induced metabolic collapse L Stuani, JE Sarry Cell Metabolism 32 (3), 321-323, 2020 | 4 | 2020 |
| Utilization of a-Ketoglutarate for Synthesis of 2-Hydroxyglutarate Oncometabolite Promotes Catabolic Flexibility, Redox Perturbation and Mitochondrial Activity That Supports … L Stuani, C Recher, JC Portais, JE Sarry Blood 130, 5080, 2017 | 4 | 2017 |
