Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response Y Haberman, R Karns, PJ Dexheimer, M Schirmer, J Somekh, I Jurickova, ... Nature communications 10 (1), 38, 2019 | 312 | 2019 |
Mitochondrial dysfunction in inflammatory bowel disease EA Novak, KP Mollen Frontiers in cell and developmental biology 3, 62, 2015 | 253 | 2015 |
Structural Dissection and In Vivo Effectiveness of a Peptide Inhibitor of Porphyromonas gingivalis Adherence to Streptococcus gordonii CA Daep, EA Novak, RJ Lamont, DR Demuth Infection and immunity 79 (1), 67-74, 2011 | 163 | 2011 |
Autoinducer-2 and QseC Control Biofilm Formation and In Vivo Virulence of Aggregatibacter actinomycetemcomitans EA Novak, HJ Shao, CA Daep, DR Demuth Infection and immunity 78 (7), 2919-2926, 2010 | 115 | 2010 |
Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation DM Previte, EC O’Connor, EA Novak, CP Martins, KP Mollen, JD Piganelli PLoS One 12 (4), e0175549, 2017 | 99 | 2017 |
Peroxisome proliferator-activated receptor-γ coactivator 1-α (PGC1α) protects against experimental murine colitis KE Cunningham, G Vincent, CP Sodhi, EA Novak, S Ranganathan, ... Journal of Biological Chemistry 291 (19), 10184-10200, 2016 | 96 | 2016 |
Treatment with a catalytic superoxide dismutase (SOD) mimetic improves liver steatosis, insulin sensitivity, and inflammation in obesity-induced type 2 diabetes GM Coudriet, MM Delmastro-Greenwood, DM Previte, ML Marré, ... Antioxidants 6 (4), 85, 2017 | 56 | 2017 |
Nix-mediated mitophagy modulates mitochondrial damage during intestinal inflammation G Vincent, EA Novak, VS Siow, KE Cunningham, BD Griffith, ... Antioxidants & redox signaling 33 (1), 1-19, 2020 | 49 | 2020 |
The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi EA Novak, SZ Sultan, MA Motaleb Frontiers in cellular and infection microbiology 4, 56, 2014 | 46 | 2014 |
The Borrelia burgdorferi CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle EA Novak, P Sekar, H Xu, KH Moon, A Manne, RM Wooten, MDA Motaleb Cellular microbiology 18 (12), 1782-1799, 2016 | 39 | 2016 |
Calcium/calmodulin–dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell … KE Cunningham, EA Novak, G Vincent, VS Siow, BD Griffith, ... The FASEB Journal 33 (1), 1330, 2018 | 21 | 2018 |
Selective substitution of amino acids limits proteolytic cleavage and improves the bioactivity of an anti-biofilm peptide that targets the periodontal pathogen, Porphyromonas … CA Daep, EA Novak, RJ Lamont, DR Demuth Peptides 31 (12), 2173-2178, 2010 | 20 | 2010 |
Eicosatetraynoic acid and butyrate regulate human intestinal organoid mitochondrial and extracellular matrix pathways implicated in Crohn’s disease strictures I Jurickova, E Bonkowski, E Angerman, E Novak, A Huron, G Akers, ... Inflammatory Bowel Diseases 28 (7), 988-1003, 2022 | 18 | 2022 |
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. Nat Commun. 2019; 10 (1): 38 Y Haberman, R Karns, PJ Dexheimer, M Schirmer, J Somekh, I Jurickova, ... DOI: https://doi. org/10.1038/s41467-018-07841-3. PMID: https://www. ncbi …, 0 | 18 | |
Cyclic GMP-AMP Synthase Contributes to Epithelial Homeostasis in Intestinal Inflammation Via Beclin-1 Mediated Autophagy S Khan, HL Mentrup, EA Novak, VS Siow, Q Wang, EC Crawford, ... FASEB journal: official publication of the Federation of American Societies …, 2022 | 15 | 2022 |
Effect of dietary cellulose supplementation on gut barrier function and apoptosis in a murine model of endotoxemia V Di Caro, AM Alcamo, JL Cummings, RSB Clark, EA Novak, KP Mollen, ... PLoS One 14 (12), e0224838, 2019 | 15 | 2019 |
Epithelial NAD+ depletion drives mitochondrial dysfunction and contributes to intestinal inflammation EA Novak, EC Crawford, HL Mentrup, BD Griffith, DM Fletcher, ... Frontiers in Immunology 14, 1231700, 2023 | 7 | 2023 |
Plant-based enteral nutrition modifies the gut microbiota and improves outcomes in murine models of colitis A Yeh, EM Conners, RG Ramos-Jimenez, B Firek, EA Novak, MB Rogers, ... Cellular and Molecular Gastroenterology and Hepatology 7 (4), 872-874. e6, 2019 | 7 | 2019 |
Mitochondrial dysfunction in inflammatory bowel disease. Front Cell Dev Biol 2015; 3: 62 EA Novak, KP Mollen | 5 | 2015 |
Alternative Autoinducer 2 Quorum‐Sensing Response Circuits: Impact on Microbial Community Development DR Demuth, E Novak, H Shao Oral microbial communities: genomic inquiry and interspecies communication …, 2011 | 5 | 2011 |